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Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice

Synaptotagmin 1 is involved in dopamine release. Here the authors investigate the effect of loss of Syt1 in midbrain dopaminergic neurons in mice, and find that unconditioned motor behaviour and motivation for food, are intact.

Benoît Delignat-Lavaud
Jana Kano
Louis-Éric Trudeau
ResearchOpen Access11 Jul 2023
Nature Communications

Volume: 14, P: 1-24

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Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice

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