Nature Search

Systemically injected oxygen within rapidly dissolving microbubbles improves the outcomes of severe hypoxaemia in swine

The intravenous injection of oxygen via polymeric microbubbles that are stable in storage yet quickly dissolve following intravenous injection led to the maintenance of critical oxygenation and to improved survival in swine with profound hypoxaemia.

Julia Garcia Mancebo
Kristen Sack
Yifeng Peng
ResearchOpen Access17 Oct 2024
Nature Biomedical Engineering

Volume: 8, P: 1396-1411
Heparan sulfate regulates amphiregulin programming of tissue reparative lung mesenchymal cells during influenza A virus infection in mice

Amphiregulin is produced by regulatory T cells to promote tissue repair and regeneration. Here the authors characterise the function of a heparan sulphate binding region in amphiregulin and show the function of this in signalling via lung mesenchymal cells to promote lung repair after influenza infection in mouse models.

Lucas F. Loffredo
Anmol Kustagi
Nicholas Arpaia
ResearchOpen Access03 Mar 2025
Nature Communications

Volume: 16, P: 1-16
Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

Different functional variants in ADH1B (and elsewhere) in Europeans and Africans strongly affect risk for alcohol dependence. Dependence only partly genetically correlates with consumption, with strong correlations to other psychiatric disorders.

Raymond K. Walters
Renato Polimanti
Arpana Agrawal
Research26 Nov 2018
Nature Neuroscience

Volume: 21, P: 1656-1669
The development of terrestrial ecosystems emerging after glacier retreat

Across 46 proglacial landscapes worldwide, environmental properties and biodiversity have shown complex patterns of change since glaciers retreated.

Gentile Francesco Ficetola
Silvio Marta
Alexis Carteron
Research31 Jul 2024
Nature

Volume: 632, P: 336-342
Spillover of highly pathogenic avian influenza H5N1 virus to dairy cattle

Spillover of the highly pathogenic avian influenza H5N1 virus to dairy cattle and the findings of a clinical, pathological and epidemiological investigation in nine affected farms are reported.

Leonardo C. Caserta
Elisha A. Frye
Diego G. Diel
ResearchOpen Access25 Jul 2024
Nature

Volume: 634, P: 669-676
Surface enhanced Raman scattering artificial nose for high dimensionality fingerprinting

Label-free surface-enhanced Raman spectroscopy is an emergent method for the detection and discrimination of biological analytes. Here, the authors describe SERS sensors with arrayed mildly-selective surface chemistries to give a fingerprint based on different interactions for analysing biological samples.

Nayoung Kim
Michael R. Thomas
Molly M. Stevens
ResearchOpen Access10 Jan 2020
Nature Communications

Volume: 11, P: 1-12
Low ¹³C-¹³C abundances in abiotic ethane

Distinguishing biotic compounds from abiotic ones is critical to the search for life in the universe. Here, the authors demonstrate that the abiotic ethane has distinctively low 13C-13C abundances compared to biotic ethane.

Koudai Taguchi
Alexis Gilbert
Yuichiro Ueno
ResearchOpen Access02 Oct 2022
Nature Communications

Volume: 13, P: 1-10
Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

Using a sample of more than 1 million individuals, Hatoum et al. identify genomic loci associated with general and substance-specific addiction risk.

Alexander S. Hatoum
Sarah M. C. Colbert
Arpana Agrawal
Research22 Mar 2023
Nature Mental Health

Volume: 1, P: 210-223
Deciphering cell states and genealogies of human haematopoiesis

An improved, single-cell lineage-tracing system, based on deep detection of naturally occurring mitochondrial DNA mutations with simultaneous readout of transcriptional states and chromatin accessibility, is used to define the clonal architecture of haematopoietic stem cells.

Chen Weng
Fulong Yu
Vijay G. Sankaran
ResearchOpen Access22 Jan 2024
Nature

Volume: 627, P: 389-398
Aβ alters the connectivity of olfactory neurons in the absence of amyloid plaques in vivo

The amyloid beta peptide can aggregate into insoluble plaques, which may indicate the onset of Alzheimer's disease. In a mouse model of Alzheimer's disease, Cao and colleagues report a phenotype of altered connectivity in the olfactory neuronal circuit that precedes amyloid plaque deposition.

Luxiang Cao
Benjamin R. Schrank
Mark W. Albers
Research21 Aug 2012
Nature Communications

Volume: 3, P: 1-10
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

Phenotypic variation and diseases are influenced by factors such as genetic variants and gene expression. Here, Barbeira et al. develop S-PrediXcan to compute PrediXcan results using summary data, and investigate the effects of gene expression variation on human phenotypes in 44 GTEx tissues and >100 phenotypes.

Alvaro N. Barbeira
Scott P. Dickinson
Hae Kyung Im
ResearchOpen Access08 May 2018
Nature Communications

Volume: 9, P: 1-20
Evolutionary dynamics and genomic features of the Elizabethkingia anophelis 2015 to 2016 Wisconsin outbreak strain

Elizabethkingia anophelis is an emerging pathogen of high antimicrobial resistance. Perrin and colleagues sequenced isolates of a 2015/2016 E. anophelis outbreak in Wisconsin and found substantial genetic diversity, accelerated evolutionary rate and a disruptive mutation in the DNA repair gene mutY.

Amandine Perrin
Elise Larsonneur
Sylvain Brisse
ResearchOpen Access24 May 2017
Nature Communications

Volume: 8, P: 1-12
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour

This genome-wide study of age at first sexual intercourse and first birth identifies 371 signals driven by reproductive biology, externalising behaviour and environmental effects, with later onset associated with lower incidence of some diseases.

Melinda C. Mills
Felix C. Tropf
Felix R. Day
Research01 Jul 2021
Nature Human Behaviour

Volume: 5, P: 1717-1730
Retrospective audit reviewing accuracy of clinical diagnosis of geographic atrophy in a single centre private tertiary retinal practice in Australia

Demi Markakis
Alexis Ceecee Britten-Jones
Heather G. Mack
ResearchOpen Access12 Mar 2025
Scientific Reports

Volume: 15, P: 1-11
Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance

Linda Richards, Paul Lockhart, Christel Depienne and colleagues identify heterozygous DCC mutations in four families and five sporadic individuals with agenesis of the corpus callosum (ACC). They report that DCC mutations result in variable dominant phenotypes with incomplete penetrance, including mirror movements and ACC associated with a favorable developmental prognosis.

Ashley P L Marsh
Delphine Heron
Christel Depienne
Research27 Feb 2017
Nature Genetics

Volume: 49, P: 511-514
Intravenous fentanyl self-administration in male and female C57BL/6J and DBA/2J mice

Michael Leonardo
Sarah Brunty
Price E. Dickson
ResearchOpen Access16 Jan 2023
Scientific Reports

Volume: 13, P: 1-12
Connectivity and population structure of albacore tuna across southeast Atlantic and southwest Indian Oceans inferred from multidisciplinary methodology

Natacha Nikolic
Iratxe Montes
Sylvain Bonhommeau
ResearchOpen Access24 Sept 2020
Scientific Reports

Volume: 10, P: 1-17
A roadmap for the atmospheric characterization of terrestrial exoplanets with JWST

The JWST has the potential to increase our understanding of terrestrial exoplanets and their atmospheres, but the various signal contaminations need to be isolated and quantified. Using JWST Cycle 1 observations of TRAPPIST-1 as a benchmark, this Perspective proposes a series of steps to use future JWST data efficiently for this purpose.

Julien de Wit
René Doyon
Michael J. Way
Reviews15 Jul 2024
Nature Astronomy

Volume: 8, P: 810-818
Shared genetic liability for alcohol consumption, alcohol problems, and suicide attempt: Evaluating the role of impulsivity

Mallory Stephenson
Séverine Lannoy
Alexis C. Edwards
ResearchOpen Access10 Mar 2023
Translational Psychiatry

Volume: 13, P: 1-8
Publisher Correction: Identification of 371 genetic variants for age at first sex and birth linked to externalising behavior

Melinda C. Mills
Felix C. Tropf
Felix R. Day
Amendments and Corrections28 Jul 2021
Nature Human Behaviour

Volume: 5, P: 1111
Survey of perspectives of people with inherited retinal diseases on ocular gene therapy in Australia

Heather G. Mack
Alexis Ceecee Britten-Jones
Lauren N. Ayton
ResearchOpen Access02 Oct 2022
Gene Therapy

Volume: 30, P: 336-346
Asymptomatic Plasmodium falciparum malaria prevalence among adolescents and adults in Malawi, 2015–2016

Hillary M. Topazian
Austin Gumbo
Jonathan J. Juliano
ResearchOpen Access30 Oct 2020
Scientific Reports

Volume: 10, P: 1-11
Clinical, environmental, and genetic risk factors for substance use disorders: characterizing combined effects across multiple cohorts

Peter B. Barr
Morgan N. Driver
Danielle M. Dick
Research04 Oct 2022
Molecular Psychiatry

Volume: 27, P: 4633-4641
A hybrid organic–inorganic polariton LED

Rahul Jayaprakash
Kyriacos Georgiou
David G. Lidzey
ResearchOpen Access04 Sept 2019
Light: Science & Applications

Volume: 8, P: 1-11
Investigating genetically stratified subgroups to better understand the etiology of alcohol misuse

Anaïs B. Thijssen
Karen Chartier
Jeanne E. Savage
ResearchOpen Access25 Jul 2023
Molecular Psychiatry

Volume: 28, P: 4225-4233

Search

Systemically injected oxygen within rapidly dissolving microbubbles improves the outcomes of severe hypoxaemia in swine

Heparan sulfate regulates amphiregulin programming of tissue reparative lung mesenchymal cells during influenza A virus infection in mice

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

The development of terrestrial ecosystems emerging after glacier retreat

Spillover of highly pathogenic avian influenza H5N1 virus to dairy cattle

Surface enhanced Raman scattering artificial nose for high dimensionality fingerprinting

Low ¹³C-¹³C abundances in abiotic ethane

Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

Deciphering cell states and genealogies of human haematopoiesis

Aβ alters the connectivity of olfactory neurons in the absence of amyloid plaques in vivo

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

Evolutionary dynamics and genomic features of the Elizabethkingia anophelis 2015 to 2016 Wisconsin outbreak strain

Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour

Retrospective audit reviewing accuracy of clinical diagnosis of geographic atrophy in a single centre private tertiary retinal practice in Australia

Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance

Intravenous fentanyl self-administration in male and female C57BL/6J and DBA/2J mice

Connectivity and population structure of albacore tuna across southeast Atlantic and southwest Indian Oceans inferred from multidisciplinary methodology

A roadmap for the atmospheric characterization of terrestrial exoplanets with JWST

Shared genetic liability for alcohol consumption, alcohol problems, and suicide attempt: Evaluating the role of impulsivity

Publisher Correction: Identification of 371 genetic variants for age at first sex and birth linked to externalising behavior

Survey of perspectives of people with inherited retinal diseases on ocular gene therapy in Australia

Asymptomatic Plasmodium falciparum malaria prevalence among adolescents and adults in Malawi, 2015–2016

Clinical, environmental, and genetic risk factors for substance use disorders: characterizing combined effects across multiple cohorts

A hybrid organic–inorganic polariton LED

Investigating genetically stratified subgroups to better understand the etiology of alcohol misuse

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