Monoclonal antibodies isolated from patients with dengue virus infection also bind to the Zika virus E protein and neutralize both Zika and dengue virus infection; the structures of two of these antibodies in complex with the Zika virus envelope protein define the binding determinants of the epitope and identify the structural basis of antibody cross neutralization.
- Giovanna Barba-Spaeth
- Wanwisa Dejnirattisai
- Félix A. Rey
