Nature Search

Onset of two-dimensional superconductivity in space charge doped few-layer molybdenum disulfide

Inducing phase transitions in atomically thin films of layered materials requires efficient electrostatic doping techniques to reach high carrier densities. Here, the authors present a doping technique which induces superconductivity by reaching high n-doping density in few-layered MoS₂on glass substrates.

Johan Biscaras
Zhesheng Chen
Abhay Shukla
ResearchOpen Access03 Nov 2015
Nature Communications

Volume: 6, P: 1-8
Engineered enzymes that retain and regenerate their cofactors enable continuous-flow biocatalysis

Tackling the loss of expensive cofactors is a key challenge in continuous-flow biocatalysis. This work reports immobilized enzymes with a tethered cofactor that is channelled between a recycling and a catalysis module facilitating total turnover numbers of NAD⁺ and ATP exceeding 10,000 in biocatalytic flow systems.

Carol J. Hartley
Charlotte C. Williams
Colin Scott
Research30 Sept 2019
Nature Catalysis

Volume: 2, P: 1006-1015
A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis

UNC5B is a Netrin-1 receptor expressed in endothelial cells that in the absence of ligand induces apoptosis. Here the authors identify an UNC5B splicing isoform that is insensitive to the pro-survival ligand Netrin-1 and is required for apoptosis-dependent blood vessel development.

Davide Pradella
Gianluca Deflorian
Claudia Ghigna
ResearchOpen Access11 Aug 2021
Nature Communications

Volume: 12, P: 1-17
Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer

We describe netrin-1 upregulation in a majority of human endometrial carcinomas and demonstrate that netrin-1 blockade, using the anti-netrin-1 antibody NP137, is effective both in a mouse model and in patients with endometrial carcinomas.

Philippe A. Cassier
Raul Navaridas
Patrick Mehlen
ResearchOpen Access02 Aug 2023
Nature

Volume: 620, P: 409-416
Dominant ARF3 variants disrupt Golgi integrity and cause a neurodevelopmental disorder recapitulated in zebrafish

Disruptions to the ER-Golgi network can lead to neurodevelopmental disorders, though our understanding of these Golgipathies remains incomplete. Here Lauri, Tartaglia and colleagues show that ARF3 mutations cause a rare pediatric neurological disorder and perform detailed molecular characterization in fish.

Giulia Fasano
Valentina Muto
Marco Tartaglia
ResearchOpen Access11 Nov 2022
Nature Communications

Volume: 13, P: 1-29
Improvement in the management of chronic obstructive pulmonary disease following a clinical educational program: results from a prospective cohort study in the Sicilian general practice setting

Rosarita Ferrara
Valentina Ientile
Gianluca Trifirò
ResearchOpen Access23 Mar 2018
npj Primary Care Respiratory Medicine

Volume: 28, P: 1-11
Novel and recurrent ALDH3A2 mutations in Italian patients with Sjögren–Larsson syndrome

Biagio Didona
Andrea Codispoti
Alessandro Terrinoni
Research28 Sept 2007
Journal of Human Genetics

Volume: 52, P: 865-870
Amino Acid Carbamates As Prodrugs Of Resveratrol

Andrea Mattarei
Michele Azzolini
Lucia Biasutto
ResearchOpen Access14 Oct 2015
Scientific Reports

Volume: 5, P: 1-11
Netrin-1 blockade inhibits tumor associated Myeloid-derived suppressor cells, cancer stemness and alleviates resistance to chemotherapy and immune checkpoint inhibitor

Benjamin Ducarouge
Anna-Rita Redavid
Agnes Bernet
Research26 Aug 2023
Cell Death & Differentiation

Volume: 30, P: 2201-2212
Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo

Magdalena Bachmann
Andrea Rossa
Ildiko Szabo
ResearchOpen Access20 Dec 2022
Cell Death & Disease

Volume: 13, P: 1-19
A Novel Inhibitor Prevents the Peripheral Neuroparalysis of Botulinum Neurotoxins

Domenico Azarnia Tehran
Giulia Zanetti
Marco Pirazzini
ResearchOpen Access16 Dec 2015
Scientific Reports

Volume: 5, P: 1-12
Death fold ___domain interaction in apoptosis

Armin Lahm
Andrea Paradisi
Gerry Melino
News25 Mar 2003
Cell Death & Differentiation

Volume: 10, P: 10-12

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Onset of two-dimensional superconductivity in space charge doped few-layer molybdenum disulfide

Engineered enzymes that retain and regenerate their cofactors enable continuous-flow biocatalysis

A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis

Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer

Dominant ARF3 variants disrupt Golgi integrity and cause a neurodevelopmental disorder recapitulated in zebrafish

Improvement in the management of chronic obstructive pulmonary disease following a clinical educational program: results from a prospective cohort study in the Sicilian general practice setting

Novel and recurrent ALDH3A2 mutations in Italian patients with Sjögren–Larsson syndrome

Amino Acid Carbamates As Prodrugs Of Resveratrol

Netrin-1 blockade inhibits tumor associated Myeloid-derived suppressor cells, cancer stemness and alleviates resistance to chemotherapy and immune checkpoint inhibitor

Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo

A Novel Inhibitor Prevents the Peripheral Neuroparalysis of Botulinum Neurotoxins

Death fold ___domain interaction in apoptosis

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