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Nature Communications (3)
Bone Research (1)

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Showing 1–4 of 4 results

Advanced filters: Author: Andrea Wilderman Clear advanced filters

A distant global control region is essential for normal expression of anterior HOXA genes during mouse and human craniofacial development

The authors discovered cluster of regulatory sequences that controls HOXA over large genomic distances and across topological domains. This cluster is required for normal craniofacial development in both humans and mice.

Andrea Wilderman
Eva D’haene
Justin Cotney
ResearchOpen Access02 Jan 2024
Nature Communications

Volume: 15, P: 1-23
Integrative analysis of transcriptome dynamics during human craniofacial development identifies candidate disease genes

Craniofacial disorders are among the most common congenital defects. Here, the authors examined the genetic causes of non-syndromic craniofacial disorders during human development through analysis of gene expression and epigenomics.

Tara N. Yankee
Sungryong Oh
Justin Cotney
ResearchOpen Access02 Aug 2023
Nature Communications

Volume: 14, P: 1-23
The G_q signalling pathway inhibits brown and beige adipose tissue

Brown and beige adipose tissues contribute to organismal energy expenditure by generating heat. Here, Klepac et al. survey G protein-coupled receptors in brown fat and show that G_q-coupled receptors inhibit expression of thermogenic proteins in mice and in human adipocytes.

Katarina Klepac
Ana Kilić
Alexander Pfeifer
ResearchOpen Access09 Mar 2016
Nature Communications

Volume: 7, P: 1-10
Enhanced osteogenic potential of iPSC-derived mesenchymal progenitor cells following genome editing of GWAS variants in the RUNX1 gene

Nazir M. Khan
Andrea Wilderman
Hicham Drissi
ResearchOpen Access06 Dec 2024
Bone Research

Volume: 12, P: 1-15