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Showing 701–750 of 850 results

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Important marine areas for endangered African penguins before and after the crucial stage of moulting

Tegan Carpenter-Kling
Andrew de Blocq
Alistair McInnes
ResearchOpen Access08 Jun 2022
Scientific Reports

Volume: 12, P: 1-13
Mendelian Randomisation study of the influence of eGFR on coronary heart disease

Pimphen Charoen
Dorothea Nitsch
Vincent Plagno
ResearchOpen Access24 Jun 2016
Scientific Reports

Volume: 6, P: 1-8
The importance of three dimensional coronary artery reconstruction accuracy when computing virtual fractional flow reserve from invasive angiography

Roshni Solanki
Rebecca Gosling
Paul D. Morris
ResearchOpen Access04 Oct 2021
Scientific Reports

Volume: 11, P: 1-12
FAIR Genomes metadata schema promoting Next Generation Sequencing data reuse in Dutch healthcare and research

K. Joeri van der Velde
Gurnoor Singh
Morris A. Swertz
ResearchOpen Access13 Apr 2022
Scientific Data

Volume: 9, P: 1-13
Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer’s Disease via Fusion of Clinical, Imaging and Omic Features

Asha Singanamalli
Haibo Wang
Kristin Fargher
ResearchOpen Access15 Aug 2017
Scientific Reports

Volume: 7, P: 1-14
International electronic health record-derived post-acute sequelae profiles of COVID-19 patients

Harrison G. Zhang
Arianna Dagliati
Griffin M. Weber
ResearchOpen Access29 Jun 2022
npj Digital Medicine

Volume: 5, P: 1-11
Analysis of potential protein-modifying variants in 9000 endometriosis patients and 150000 controls of European ancestry

Yadav Sapkota
Immaculata De Vivo
Grant W. Montgomery
ResearchOpen Access12 Sept 2017
Scientific Reports

Volume: 7, P: 1-11
The changing state of porous materials

Highly ordered crystalline porous solids are useful for many applications. This Perspective explores the evolution of these systems from the ordered state to the glassy and liquid states, discusses the different types of porous liquid and considers possible applications of these disordered systems.

Thomas D. Bennett
François-Xavier Coudert
Andrew I. Cooper
Reviews15 Apr 2021
Nature Materials

Volume: 20, P: 1179-1187
Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction

Zhou et al. utilise deep learning to improve polygenic risk analysis for Alzheimer’s disease. Their computational approach outperforms existing statistical methods and helps to identify potential biological mechanisms of Alzheimer’s disease risk.

Xiaopu Zhou
Yu Chen
Nancy Y. Ip
ResearchOpen Access06 Apr 2023
Communications Medicine

Volume: 3, P: 1-20
Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90

Laura Heath
John C. Earls
Yi Zhao
ResearchOpen Access12 Apr 2022
Scientific Reports

Volume: 12, P: 1-17
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Till F. M. Andlauer
Jose Guzman-Parra
Marcella Rietschel
ResearchOpen Access11 Nov 2019
Molecular Psychiatry

Volume: 26, P: 1286-1298
Comorbid depression in medical diseases

Major depressive disorder is common in patients with medical diseases and accounts for a substantial part of the psychosocial burden of these diseases. This Primer discusses the epidemiology, mechanisms, diagnosis and treatment of comorbid depression in patients with medical diseases.

Stefan M. Gold
Ole Köhler-Forsberg
Christian Otte
Reviews20 Aug 2020
Nature Reviews Disease Primers

Volume: 6, P: 1-22
Plasma organochlorine levels and prostate cancer risk

Kristan J Aronson
James W L Wilson
Alvara Morales
Research10 Jun 2009
Journal of Exposure Science & Environmental Epidemiology

Volume: 20, P: 434-445
Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity

Audrey E. Hendricks
Elena G. Bochukova
Hou-Feng Zheng
ResearchOpen Access29 Jun 2017
Scientific Reports

Volume: 7, P: 1-14
Epigenome-wide association study of alcohol consumption in N = 8161 individuals and relevance to alcohol use disorder pathophysiology: identification of the cystine/glutamate transporter SLC7A11 as a top target

Falk W. Lohoff
Toni-Kim Clarke
Kathryn L. Evans
ResearchOpen Access02 Dec 2021
Molecular Psychiatry

Volume: 27, P: 1754-1764
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

Alberto Romagnoni
Simon Jégou
Pamela Whittaker
ResearchOpen Access17 Jul 2019
Scientific Reports

Volume: 9, P: 1-18
Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder

Xiaoming Jia
Fernando S. Goes
Laura J. Scott
ResearchOpen Access22 Jan 2021
Molecular Psychiatry

Volume: 26, P: 5239-5250
Genome-wide methylation analyses identifies Non-coding RNA genes dysregulated in breast tumours that metastasise to the brain

Rajendra P. Pangeni
Ivonne Olivaries
Mark R. Morris
ResearchOpen Access20 Jan 2022
Scientific Reports

Volume: 12, P: 1-14
Staging tau pathology with tau PET in Alzheimer’s disease: a longitudinal study

Shi-Dong Chen
Jia-Ying Lu
Michelle Zmuda
ResearchOpen Access18 Sept 2021
Translational Psychiatry

Volume: 11, P: 1-12
The promise of organ and tissue preservation to transform medicine

Sebastian Giwa
Jedediah K Lewis
Mehmet Toner
Reviews07 Jun 2017
Nature Biotechnology

Volume: 35, P: 530-542
Large scale proteomic studies create novel privacy considerations

Andrew C. Hill
Claire Guo
Russell P. Bowler
ResearchOpen Access07 Jun 2023
Scientific Reports

Volume: 13, P: 1-14
Mining Outcome-relevant Brain Imaging Genetic Associations via Three-way Sparse Canonical Correlation Analysis in Alzheimer’s Disease

Xiaoke Hao
Chanxiu Li
Kristin Fargher
ResearchOpen Access14 Mar 2017
Scientific Reports

Volume: 7, P: 1-12
Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2

Denise G. O’Mahony
Susan J. Ramus
Elizabeth Santana dos Santos
ResearchOpen Access19 Apr 2023
British Journal of Cancer

Volume: 128, P: 2283-2294
Behavioral and Neurochemical Alterations in Mice Deficient in Anaplastic Lymphoma Kinase Suggest Therapeutic Potential for Psychiatric Indications

James G Bilsland
Alan Wheeldon
Ignacio Munoz-Sanjuan
Research09 May 2007
Neuropsychopharmacology

Volume: 33, P: 685-700
Functional long-range RNA–RNA interactions in positive-strand RNA viruses

Long-range intragenomic RNA–RNA interactions in the genomes of positive-strand RNA viruses involve direct nucleotide base pairing and can span distances of thousands of nucleotides. In this Review, Nicholson and White discuss recent insights into the structure and function of these genomic features and highlight their diverse roles in the gene expression and genome replication of positive-strand RNA viruses.

Beth L. Nicholson
K. Andrew White
Reviews16 Jun 2014
Nature Reviews Microbiology

Volume: 12, P: 493-504
The International HapMap Project

Richard A. Gibbs
John W. Belmont
Toshihiro Tanaka
Special Features18 Dec 2003
Nature

Volume: 426, P: 789-796
Effect of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy, mild cognitive impairment and Alzheimer’s disease cohorts

Lin Tan
Hui-Fu Wang
Kristin Fargher
ResearchOpen Access27 May 2016
Scientific Reports

Volume: 6, P: 1-12
Identifying prescribers of antibiotics in a primary care spinal cord injury cohort

Arrani Senthinathan
Melanie Penner
Susan B. Jaglal
Research01 Feb 2024
Spinal Cord Series and Cases

Volume: 10, P: 1-7
Rethinking the words hotspot reservoir and pristine in the environmental dimensions of antimicrobial resistance

Richard Helliwell
Isabel Ewin
Dov J. Stekel
ReviewsOpen Access21 Feb 2025
npj Antimicrobials and Resistance

Volume: 3, P: 1-7
Robust Identification of Alzheimer’s Disease subtypes based on cortical atrophy patterns

Jong-Yun Park
Han Kyu Na
Balebail Ashok Raj
ResearchOpen Access09 Mar 2017
Scientific Reports

Volume: 7, P: 1-14
The E3 ligase HUWE1 inhibition as a therapeutic strategy to target MYC in multiple myeloma

Lisa J. Crawford
David C. Campbell
Alexandra E. Irvine
ResearchOpen Access10 Jun 2020
Oncogene

Volume: 39, P: 5001-5014
Rare copy number variation in posttraumatic stress disorder

Adam X. Maihofer
Worrawat Engchuan
Caroline M. Nievergelt
ResearchOpen Access21 Sept 2022
Molecular Psychiatry

Volume: 27, P: 5062-5069
1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans

Ida E. Sønderby
Dennis van der Meer
Marianne B. M. van den Bree
ResearchOpen Access22 Mar 2021
Translational Psychiatry

Volume: 11, P: 1-16
Group 2 innate lymphoid cells (ILC2) are regulated by stem cell factor during chronic asthmatic disease

Wendy Fonseca
Andrew J Rasky
Nicholas W. Lukacs
Research07 Jan 2019
Mucosal Immunology

Volume: 12, P: 445-456
Author Correction: Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease

Eva Gonçalves Serra
Tobias Schwerd
Carl A. Anderson
Amendments and CorrectionsOpen Access22 Jun 2022
Nature Communications

Volume: 13, P: 1
Multimodal Hippocampal Subfield Grading For Alzheimer’s Disease Classification

Kilian Hett
Vinh-Thong Ta
Kristin Fargher
ResearchOpen Access25 Sept 2019
Scientific Reports

Volume: 9, P: 1-16
A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data

Suprateek Kundu
Joshua Lukemire
Ansgar J. Furst
ResearchOpen Access20 Dec 2019
Scientific Reports

Volume: 9, P: 1-18
Transformation Systems for Generating Marker–Free Transgenic Plants

John I. Yoder
Andrew P. Goldsbrough
Reviews01 Mar 1994
Bio/Technology

Volume: 12, P: 263-267
Genome-wide association study of developmental dysplasia of the hip identifies an association with GDF5

Konstantinos Hatzikotoulas et al. report the largest genome-wide association study to date for developmental dysplasia of the hip using national clinical audit data from the UK. They find a significant association with the GDF5 locus and evidence for shared genetic architecture with hip osteoarthritis.

Konstantinos Hatzikotoulas
Andreas Roposch
J. Mark Wilkinson
ResearchOpen Access31 May 2018
Communications Biology

Volume: 1, P: 1-11
Manganese uptake in marine bacteria; the novel MntX transporter is widespread in Roseobacters, Vibrios, Alteromonadales and the SAR11 and SAR116 clades

Robert T Green
Jonathan D Todd
Andrew W B Johnston
Research29 Nov 2012
The ISME Journal

Volume: 7, P: 581-591
Integrated genomics point to immune vulnerabilities in pleural mesothelioma

Anca Nastase
Amit Mandal
William O. C. M. Cookson
ResearchOpen Access27 Sept 2021
Scientific Reports

Volume: 11, P: 1-15
Multi-modality machine learning predicting Parkinson’s disease

Mary B. Makarious
Hampton L. Leonard
Mike A. Nalls
ResearchOpen Access01 Apr 2022
npj Parkinson's Disease

Volume: 8, P: 1-13
Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders

Carine Thalman
Guilherme Horta
Johannes Vogt
ResearchOpen Access09 May 2018
Molecular Psychiatry

Volume: 23, P: 1699-1710
The impact of the COVID-19 pandemic upon pancreatic cancer treatment (CONTACT Study): a UK national observational cohort study

Lewis A. Hall
Siobhan C. McKay
Melissa Zhao
ResearchOpen Access23 Mar 2023
British Journal of Cancer

Volume: 128, P: 1922-1932
The predictive ability of the 313 variant–based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant

Inge M. M. Lakeman
Alexandra J. van den Broek
Marjanka K. Schmidt
ResearchOpen Access10 Jun 2021
Genetics in Medicine

Volume: 23, P: 1726-1737
Correlation between Alzheimer’s disease and type 2 diabetes using non-negative matrix factorization

Yeonwoo Chung
Hyunju Lee
Kristin Fargher
ResearchOpen Access27 Jul 2021
Scientific Reports

Volume: 11, P: 1-14
A novel point mutation in the mitochondrial tRNA^Trp gene produces a neurogastrointestinal syndrome

Katharina Maniura-Weber
Robert W Taylor
Laurence A Bindoff
Research31 Mar 2004
European Journal of Human Genetics

Volume: 12, P: 509-512
Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer’s disease

Meiyan Huang
Wei Yang
Kristin Fargher
ResearchOpen Access12 Jan 2017
Scientific Reports

Volume: 7, P: 1-13
Uric acid pathway activation during respiratory virus infection promotes Th2 immune response via innate cytokine production and ILC2 accumulation

Wendy Fonseca
Carrie-Anne Malinczak
Nicholas W. Lukacs
Research11 Feb 2020
Mucosal Immunology

Volume: 13, P: 691-701
The impact of PICALM genetic variations on reserve capacity of posterior cingulate in AD continuum

Wei Xu
Hui-Fu Wang
Kristin Fargher
ResearchOpen Access27 Apr 2016
Scientific Reports

Volume: 6, P: 1-11

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