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Showing 1–2 of 2 results
Advanced filters: Author: Anjana Nityanandam Clear advanced filters

  • Smad-interacting protein 1 (Sip1) is a transcriptional repressor that acts in the TGF-β signaling pathway. This study finds that Sip1 is involved in a feedback signaling mechanism in which newly generated postmitotic cells in neocortical layers instruct progenitor cells for proper cell-fate switch and proliferation.

    • Eve Seuntjens
    • Anjana Nityanandam
    • Victor Tarabykin
    Research
    Nature Neuroscience
    Volume: 12, P: 1373-1380

  • Retinoblastoma is a heritable pediatric cancer driven by mutations in RB1. Here, the authors demonstrate the first patient derived model of retinoblastoma using iPSCs from patients with germline mutations in RB1.

    • Jackie L. Norrie
    • Anjana Nityanandam
    • Michael A. Dyer
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-13