Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–5 of 5 results
Advanced filters: Author: Anne Offermann Clear advanced filters

  • Urothelial cancer is a challenging disease and an emerging field for targeted therapies. Here, the authors optimize clinical proteomics to provide proteome-level data on tumor specificity and identify robust prognostic subtypes with predictive information for repurposed drug candidates.

    • Franz F. Dressler
    • Falk Diedrichs
    • Ákos Végvári
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-19

  • Immune checkpoints blockade (ICB) is a viable anti-cancer strategy. Here the authors show that nuclear receptor NR2F6 acts as an immune checkpoint in T cells and, using mouse models and human T cells, they show NR2F6 inhibition might improve current ICB therapy or work as an alternative therapeutic strategy.

    • Victoria Klepsch
    • Natascha Hermann-Kleiter
    • Gottfried Baier
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13

  • KMT9, a new histone lysine methyltransferase targeting H4K12, is enriched at promoters of genes encoding molecules involved in the cell cycle and controls the growth of androgen receptor–dependent and castration- and enzalutamide-resistant prostate cancer cells and xenograft tumors.

    • Eric Metzger
    • Sheng Wang
    • Roland Schüle
    Research
    Nature Structural & Molecular Biology
    Volume: 26, P: 361-371

  • In this Review, the authors provide a comprehensive overview of various in vitro, ex vivo and in vivo models of prostate cancer and discuss their respective advantages and limitations in the context of current needs and challenges in prostate cancer research and therapy.

    • Verena Sailer
    • Gunhild von Amsberg
    • Achim Aigner
    Reviews
    Nature Reviews Urology
    Volume: 20, P: 158-178