Nature Search

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion

A study of SARS-CoV-2 variants examining their transmission, infectivity, and potential resistance to therapies provides insights into the biology of the Delta variant and its role in the global pandemic.

Petra Mlcochova
Steven A. Kemp
Ravindra K. Gupta
ResearchOpen Access06 Sept 2021
Nature

Volume: 599, P: 114-119
India’s COVID crisis flags need to forecast variants

The rise of more-transmissible viral mutants demands new ways to prevent, detect, track and treat SARS-CoV-2 infections.

Anurag Agrawal
Comments & Opinion01 Jun 2021
Nature

Volume: 594, P: 9
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Domatia mediate plantarthropod mutualism

Anurag A. Agrawal
Richard Karban
Research05 Jun 1997
Nature

Volume: 387, P: 562-563
Urbanization and a green corridor do not impact genetic divergence in common milkweed (Asclepias syriaca L.)

Sophie T. Breitbart
Anurag A. Agrawal
Marc T. J. Johnson
ResearchOpen Access22 Nov 2023
Scientific Reports

Volume: 13, P: 1-16
Transgenerational induction of defences in animals and plants

Anurag A. Agrawal
Christian Laforsch
Ralph Tollrian
Research02 Sept 1999
Nature

Volume: 401, P: 60-63
High failure rate of ChAdOx1-nCoV19 immunization against asymptomatic infection in healthcare workers during a Delta variant surge

The authors study a cohort of healthcare workers in India who received two doses of the ChAdOx-1-nCoV19 vaccine during the Delta wave. Using serological data, they infer that 25% of the cohort were infected within 60 days of vaccination, although there were no severe infections leading to hospitalisations.

Rajat Ujjainiya
Akansha Tyagi
Shantanu Sengupta
ResearchOpen Access01 Apr 2022
Nature Communications

Volume: 13, P: 1-6
Refractory inflammatory bowel disease—could it be an irritable bowel?

Patients with IBD who are reportedly in remission, but continue to have symptoms of abdominal discomfort and bowel dysfunction, could have IBS in addition to IBD. This Perspectives article examines the relationship between IBS and IBD, and discusses how to diagnose and treat IBS in patients with co-existing IBD.

Jie Meng
Anurag Agrawal
Peter J. Whorwell
Reviews11 Sept 2012
Nature Reviews Gastroenterology & Hepatology

Volume: 10, P: 58-61
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
An updated framework for SARS-CoV-2 variants reflects the unpredictability of viral evolution

The World Health Organization framework for tracking SARS-CoV-2 variants has been updated to reflect the continued evolution of the virus; this framework could be adapted for other emerging respiratory diseases with epidemic and pandemic potential.

Lorenzo Subissi
James Richard Otieno
Maria D. Van Kerkhove
Comments & Opinion08 May 2024
Nature Medicine

Volume: 30, P: 2400-2403
Loss-of-function of inositol polyphosphate-4-phosphatase reversibly increases the severity of allergic airway inflammation

Inositol polyphosphate 4 phosphatase regulates phosphoinositide signalling and is associated with an increased risk of asthma. Aichet al. show that, in a mouse model of airway inflammation, calpains degrade inositol polyphosphate 4 phosphatase resulting in exacerbated phosphoinositide 3-kinase signalling.

Jyotirmoi Aich
Ulaganathan Mabalirajan
Balaram Ghosh
Research06 Jun 2012
Nature Communications

Volume: 3, P: 1-11
Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Fine-scale geospatial mapping of overweight and wasting (two components of the double burden of malnutrition) in 105 LMICs shows that overweight has increased from 5.2% in 2000 to 6.0% in children under 5 in 2017. Although overall wasting decreased over the same period, most countries are not on track to meet the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025.

Damaris K. Kinyoki
Jennifer M. Ross
Simon I. Hay
ResearchOpen Access20 Apr 2020
Nature Medicine

Volume: 26, P: 750-759
A multinational Delphi consensus to end the COVID-19 public health threat

A diverse, multidisciplinary panel of 386 experts in COVID-19 response from 112 countries provides health and social policy actions to address inadequacies in the pandemic response and help to bring this public health threat to an end.

Jeffrey V. Lazarus
Diana Romero
Anne Øvrehus
ResearchOpen Access03 Nov 2022
Nature

Volume: 611, P: 332-345
Subclinical pulmonary dysfunction contributes to high altitude pulmonary edema susceptibility in healthy non-mountaineers

Rajinder K. Gupta
Poonam Soree
Shashi Bala Singh
ResearchOpen Access02 Nov 2017
Scientific Reports

Volume: 7, P: 1-7
Elevated pulmonary artery pressure and brain natriuretic peptide in high altitude pulmonary edema susceptible non-mountaineers

Rajinder K. Gupta
G. Himashree
Shashi Bala Singh
ResearchOpen Access19 Feb 2016
Scientific Reports

Volume: 6, P: 1-8
Raised HIF1α during normoxia in high altitude pulmonary edema susceptible non-mountaineers

Poonam Soree
Rajinder K. Gupta
Shashi Bala Singh
ResearchOpen Access23 May 2016
Scientific Reports

Volume: 6, P: 1-7
Publisher Correction: Super-resolution fight club: assessment of 2D and 3D single-molecule localization microscopy software

Daniel Sage
Thanh-An Pham
Seamus Holden
Amendments and Corrections16 May 2019
Nature Methods

Volume: 16, P: 561
Super-resolution fight club: assessment of 2D and 3D single-molecule localization microscopy software

This study reports results from the second community-wide single-molecule localization microscopy software challenge, which tested over 30 software packages on realistic simulated data for multiple popular 3D image acquisition modes, as well as 2D localization microscopy.

Daniel Sage
Thanh-An Pham
Seamus Holden
Research08 Apr 2019
Nature Methods

Volume: 16, P: 387-395
An early warning system for emerging SARS-CoV-2 variants

Global sequencing and surveillance capacity for SARS-CoV-2 must be strengthened and combined with multidisciplinary studies of infectivity, virulence and immune escape, in order to track the unpredictable evolution of the ongoing COVID-19 pandemic.

Lorenzo Subissi
Anne von Gottberg
Anurag Agrawal
Comments & Opinion30 May 2022
Nature Medicine

Volume: 28, P: 1110-1115
Design principles for lifelong learning AI accelerators

The Perspective explores the future design of lifelong learning artificial intelligence (AI) accelerators that are intended for deployment in untethered environments, identifying key desirable capabilities for such edge AI accelerators and guidance on metrics to evaluate them.

Dhireesha Kudithipudi
Anurag Daram
Benjamin Epstein
Reviews16 Nov 2023
Nature Electronics

Volume: 6, P: 807-822
Validation of expert system enhanced deep learning algorithm for automated screening for COVID-Pneumonia on chest X-rays

Prashant Sadashiv Gidde
Shyam Sunder Prasad
Debasis Dash
ResearchOpen Access01 Dec 2021
Scientific Reports

Volume: 11, P: 1-12
Obesity impairs cardiolipin-dependent mitophagy and therapeutic intercellular mitochondrial transfer ability of mesenchymal stem cells

Shakti Sagar
Md Imam Faizan
Soumya Sinha Roy
ResearchOpen Access13 May 2023
Cell Death & Disease

Volume: 14, P: 1-19
Genome editing retraces the evolution of toxin resistance in the monarch butterfly

CRISPR–Cas9 engineering of the Drosophila Atpα gene (encoding the α-subunit of the sodium pump) is used to study the ability of mutations that evolved independently in several insect orders to confer resistance to keystone plant toxins.

Marianthi Karageorgi
Simon C. Groen
Noah K. Whiteman
Research02 Oct 2019
Nature

Volume: 574, P: 409-412
Somatic mutational landscape across Indian breast cancer cases by whole exome sequencing

Rahul Kumar
Supriya Awasthi
Pranay Tanwar
ResearchOpen Access12 Aug 2024
Scientific Reports

Volume: 14, P: 1-11
Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Damaris K. Kinyoki
Jennifer M. Ross
Simon I. Hay
Amendments and CorrectionsOpen Access02 Jul 2020
Nature Medicine

Volume: 26, P: 1308
Genetic variations in olfactory receptor gene OR2AG2 in a large multigenerational family with asthma

Samarpana Chakraborty
Pushkar Dakle
Anurag Agrawal
ResearchOpen Access13 Dec 2019
Scientific Reports

Volume: 9, P: 1-10
Mechanisms and evolution of plant resistance to aphids

Tobias Züst
Anurag A. Agrawal
Reviews06 Jan 2016
Nature Plants

Volume: 2, P: 1-9
Hyperglycemia is associated with duodenal dysbiosis and altered duodenal microenvironment

Aarti Darra
Vandana Singh
Usha Dutta
ResearchOpen Access07 Jul 2023
Scientific Reports

Volume: 13, P: 1-14
Transmission of B.1.617.2 Delta variant between vaccinated healthcare workers

Steven A. Kemp
Mark T. K. Cheng
Ravindra K. Gupta
ResearchOpen Access21 Jun 2022
Scientific Reports

Volume: 12, P: 1-11
Simvastatin mediates inhibition of exosome synthesis, localization and secretion via multicomponent interventions

Ankur Kulshreshtha
Swati Singh
Balaram Ghosh
ResearchOpen Access08 Nov 2019
Scientific Reports

Volume: 9, P: 1-10
Linoleic acid metabolite drives severe asthma by causing airway epithelial injury

Ulaganathan Mabalirajan
Rakhshinda Rehman
Balaram Ghosh
ResearchOpen Access27 Feb 2013
Scientific Reports

Volume: 3, P: 1-12
12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma

Ulaganathan Mabalirajan
Rakhshinda Rehman
Balaram Ghosh
ResearchOpen Access26 Mar 2013
Scientific Reports

Volume: 3, P: 1-11
Detecting the Molecular System Signatures of Idiopathic Pulmonary Fibrosis through Integrated Genomic Analysis

Indu Gangwar
Nitesh Kumar Sharma
Ravi Shankar
ResearchOpen Access08 May 2017
Scientific Reports

Volume: 7, P: 1-11
Changes of the human gut microbiome induced by a fermented milk product

Patrick Veiga
Nicolas Pons
Sean P. Kennedy
ResearchOpen Access11 Sept 2014
Scientific Reports

Volume: 4, P: 1-9
Linoleic acid metabolite leads to steroid resistant asthma features partially through NF-κB

Lipsa Panda
Atish Gheware
Ulaganathan Mabalirajan
ResearchOpen Access29 Aug 2017
Scientific Reports

Volume: 7, P: 1-11
Genetic association of key Th1/Th2 pathway candidate genes, IRF2, IL6, IFNGR2, STAT4 and IL4RA, with atopic asthma in the Indian population

Amrendra Kumar
Sudipta Das
Balaram Ghosh
Research21 May 2015
Journal of Human Genetics

Volume: 60, P: 443-448

Search

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion

India’s COVID crisis flags need to forecast variants

Whole-genome sequencing reveals host factors underlying critical COVID-19

Domatia mediate plantarthropod mutualism

Urbanization and a green corridor do not impact genetic divergence in common milkweed (Asclepias syriaca L.)

Transgenerational induction of defences in animals and plants

High failure rate of ChAdOx1-nCoV19 immunization against asymptomatic infection in healthcare workers during a Delta variant surge

Refractory inflammatory bowel disease—could it be an irritable bowel?

Mapping the human genetic architecture of COVID-19

An updated framework for SARS-CoV-2 variants reflects the unpredictability of viral evolution

Loss-of-function of inositol polyphosphate-4-phosphatase reversibly increases the severity of allergic airway inflammation

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

A multinational Delphi consensus to end the COVID-19 public health threat

Subclinical pulmonary dysfunction contributes to high altitude pulmonary edema susceptibility in healthy non-mountaineers

Elevated pulmonary artery pressure and brain natriuretic peptide in high altitude pulmonary edema susceptible non-mountaineers

Raised HIF1α during normoxia in high altitude pulmonary edema susceptible non-mountaineers

Publisher Correction: Super-resolution fight club: assessment of 2D and 3D single-molecule localization microscopy software

Super-resolution fight club: assessment of 2D and 3D single-molecule localization microscopy software

An early warning system for emerging SARS-CoV-2 variants

Design principles for lifelong learning AI accelerators

Validation of expert system enhanced deep learning algorithm for automated screening for COVID-Pneumonia on chest X-rays

Obesity impairs cardiolipin-dependent mitophagy and therapeutic intercellular mitochondrial transfer ability of mesenchymal stem cells

Genome editing retraces the evolution of toxin resistance in the monarch butterfly

Somatic mutational landscape across Indian breast cancer cases by whole exome sequencing

Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Genetic variations in olfactory receptor gene OR2AG2 in a large multigenerational family with asthma

Mechanisms and evolution of plant resistance to aphids

Hyperglycemia is associated with duodenal dysbiosis and altered duodenal microenvironment

Transmission of B.1.617.2 Delta variant between vaccinated healthcare workers

Simvastatin mediates inhibition of exosome synthesis, localization and secretion via multicomponent interventions

Linoleic acid metabolite drives severe asthma by causing airway epithelial injury

12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma

Detecting the Molecular System Signatures of Idiopathic Pulmonary Fibrosis through Integrated Genomic Analysis

Changes of the human gut microbiome induced by a fermented milk product

Linoleic acid metabolite leads to steroid resistant asthma features partially through NF-κB

Genetic association of key Th1/Th2 pathway candidate genes, IRF2, IL6, IFNGR2, STAT4 and IL4RA, with atopic asthma in the Indian population

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