Nature Search

Author Correction: Mapping genetic diversity with the GenomeIndia project

Chandrika Bhattacharyya
Krithika Subramanian
Bratati Kahali
Amendments and Corrections08 May 2025
Nature Genetics

Volume: 57, P: 1563
The COVIDTrach prospective cohort study on outcomes in 1982 tracheostomised COVID-19 patients during the first and second UK pandemic waves

Matthew Haywood
Gareth Ambler
Andrzej Sladkowski
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-12
Mapping genetic diversity with the GenomeIndia project

The rich ethnolinguistic and sociocultural differences that exist in India offers a unique opportunity to study human diversity. With the whole genomes of 10,000 healthy and unrelated Indians from 83 populations, the GenomeIndia project captures the genetic diversity of one of the highly underrepresented populations in the global genomics landscape.

Chandrika Bhattacharyya
Krithika Subramanian
Bratati Kahali
Comments & Opinion08 Apr 2025
Nature Genetics

Volume: 57, P: 767-773
Author Correction: Spatial multiplexing and omics

Julienne L. Carstens
Santhoshi N. Krishnan
Jared K. Burks
Amendments and Corrections02 Sept 2024
Nature Reviews Methods Primers

Volume: 4, P: 1
Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
Federated learning enables big data for rare cancer boundary detection

Federated ML (FL) provides an alternative to train accurate and generalizable ML models, by only sharing numerical model updates. Here, the authors present the largest FL study to-date to generate an automatic tumor boundary detector for glioblastoma.

Sarthak Pati
Ujjwal Baid
Spyridon Bakas
ResearchOpen Access05 Dec 2022
Nature Communications

Volume: 13, P: 1-17
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs

Glycinergic synapses play a central role in motor control and pain processing in the central nervous system. Here, authors present cryo-EM structures of the full-length glycine receptors (GlyRs) reconstituted into lipid nanodiscs in the unliganded, glycine-bound and allosteric modulator-bound conformations and reveal global conformational changes underlying GlyR channel gating and modulation.

Arvind Kumar
Sandip Basak
Sudha Chakrapani
ResearchOpen Access27 Jul 2020
Nature Communications

Volume: 11, P: 1-14
Structural basis for cannabinoid-induced potentiation of alpha1-glycine receptors in lipid nanodiscs

Glycine receptors (GlyRs) mediate motor control and pain perception. Here, Kumar et al. present structures of GlyR bound to Δ9 -tetrahydrocannabinol (THC) using cryo-electron microscopy, providing insight into the therapeutic effects of cannabinoids.

Arvind Kumar
Kayla Kindig
Sudha Chakrapani
ResearchOpen Access18 Aug 2022
Nature Communications

Volume: 13, P: 1-14
Comprehensive molecular characterization of gastric adenocarcinoma

The Cancer Genome Atlas reports on molecular evaluation of 295 primary gastric adenocarcinomas and proposes a new classification of gastric cancers into 4 subtypes, which should help with clinical assessment and trials of targeted therapies.

Adam J. Bass
Vesteinn Thorsson
Jia Liu
ResearchOpen Access23 Jul 2014
Nature

Volume: 513, P: 202-209
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
The genetic heterogeneity and drug resistance mechanisms of relapsed refractory multiple myeloma

The genetic factors involved in disease progression and drug resistance in multiple myeloma (MM) are varied and complex. Here, genomic and transcriptomic profiling of 511 relapsed and refractory MM patients reveals genetic alterations in several oncogenic pathways contributing to progression and resistance to MM therapies.

Josh N. Vo
Yi-Mi Wu
Arul M. Chinnaiyan
ResearchOpen Access29 Jun 2022
Nature Communications

Volume: 13, P: 1-13
Evaluating the climate impact of aviation emission scenarios towards the Paris agreement including COVID-19 effects

Aviation contributes to climate change and ways to reduce its emissions are widely debated. Here, the authors assess the effects of technology improvements and the use of sustainable aviation fuels and find that even when these are considered aviation is unlikely to meet emissions goals in line with the Paris Agreement.

Volker Grewe
Arvind Gangoli Rao
Katrin Dahlmann
ResearchOpen Access22 Jun 2021
Nature Communications

Volume: 12, P: 1-10
Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis

After lung injury, Kobayashi, Tata et al. find an intermediate cell state during the transition of alveolar type-2 into type-1 cells that is associated with senescence, controlled by TP53 and persists in fibrosis.

Yoshihiko Kobayashi
Aleksandra Tata
Purushothama Rao Tata
Research13 Jul 2020
Nature Cell Biology

Volume: 22, P: 934-946
Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment

Nephrotic syndrome is the second most common chronic kidney disease but there are no targeted treatment strategies available. Here the authors identify mutations of six genes codifying for proteins involved in cytoskeleton remodelling and modulation of small GTPases in 17 families with nephrotic syndrome.

Shazia Ashraf
Hiroki Kudo
Friedhelm Hildebrandt
ResearchOpen Access17 May 2018
Nature Communications

Volume: 9, P: 1-14
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer

The functional significance of T-cell infiltration in pancreatic ductal adenocarcinoma in relation to desmoplastic stroma is unclear. Here the authors develop a method to spatially resolve tumour stroma composition and find that spatial T-cell infiltration correlates with patient prognosis regardless of desmoplasia.

Julienne L. Carstens
Pedro Correa de Sampaio
Raghu Kalluri
ResearchOpen Access27 Apr 2017
Nature Communications

Volume: 8, P: 1-13
Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Contrary to the view that urbanization is a major driver of the global rise in obesity, the global increase in body-mass index is shown to be mostly due to increases in the body-mass indexes of rural populations.

Honor Bixby
James Bentham
Majid Ezzati
ResearchOpen Access08 May 2019
Nature

Volume: 569, P: 260-264
Spatial multiplexing and omics

Spatial multiomics is an interdisciplinary field combining all molecular omics using advanced imaging techniques to explore interactions within tissues and cells. In this Primer, Carstens et al. examine current technologies for quantification across biological scales and discuss considerations for establishing cross-disciplinary projects.

Julienne L. Carstens
Santhoshi N. Krishnan
Jared K. Burks
Reviews01 Aug 2024
Nature Reviews Methods Primers

Volume: 4, P: 1-19
Multimodal mapping of the tumor and peripheral blood immune landscape in human pancreatic cancer

Using single-cell RNA sequencing, CyTOF and multiplex immunohistochemistry, Steele et al. survey the immune landscape in pancreatic cancers, adjacent tissue and blood, observing heterogeneous immune checkpoint receptor expression within patients.

Nina G. Steele
Eileen S. Carpenter
Marina Pasca di Magliano
Research26 Oct 2020
Nature Cancer

Volume: 1, P: 1097-1112
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Association of graph-based spatial features with overall survival status of glioblastoma patients

Joonsang Lee
Shivali Narang
Arvind Rao
ResearchOpen Access09 Oct 2023
Scientific Reports

Volume: 13, P: 1-11
Density-based classification in diabetic retinopathy through thickness of retinal layers from optical coherence tomography

Shariq Mohammed
Tingyang Li
Arvind Rao
ResearchOpen Access28 Sept 2020
Scientific Reports

Volume: 10, P: 1-13
Unsupervised machine learning for identifying important visual features through bag-of-words using histopathology data from chronic kidney disease

Joonsang Lee
Elisa Warner
Arvind Rao
ResearchOpen Access22 Mar 2022
Scientific Reports

Volume: 12, P: 1-13
Author Correction: Federated learning enables big data for rare cancer boundary detection

Sarthak Pati
Ujjwal Baid
Spyridon Bakas
Amendments and CorrectionsOpen Access26 Jan 2023
Nature Communications

Volume: 14, P: 1-2
Anterior Cingulate and Frontal Lobe White Matter Spectroscopy in Early Childhood of Former Very LBW Premature Infants

John P Phillips
David Ruhl
Jean R Lowe
Research01 Mar 2011
Pediatric Research

Volume: 69, P: 224-229
Position statement on hypertension by Indian Society of Hypertension, 2023

Anuj Maheshwari
Rajeev Gupta
A. Muruganathan
Reviews04 Oct 2024
Journal of Human Hypertension

Volume: 38, P: 736-744
Clustering-based spatial analysis (CluSA) framework through graph neural network for chronic kidney disease prediction using histopathology images

Joonsang Lee
Elisa Warner
Arvind Rao
ResearchOpen Access05 Aug 2023
Scientific Reports

Volume: 13, P: 1-14
Immune modulation by molecularly targeted photothermal ablation in a mouse model of advanced hepatocellular carcinoma and cirrhosis

Nina M. Muñoz
Crystal Dupuis
Rahul A. Sheth
ResearchOpen Access24 Aug 2022
Scientific Reports

Volume: 12, P: 1-12
GaWRDenMap: a quantitative framework to study the local variation in cell–cell interactions in pancreatic disease subtypes

Santhoshi N. Krishnan
Shariq Mohammed
Arvind Rao
ResearchOpen Access08 Mar 2022
Scientific Reports

Volume: 12, P: 1-11
Deficiency of phyto-available sulphur, zinc, boron, iron, copper and manganese in soils of India

Arvind Kumar Shukla
Sanjib Kumar Behera
Anil Kumar Singh
ResearchOpen Access05 Oct 2021
Scientific Reports

Volume: 11, P: 1-13
Cellular engagement and interaction in the tumor microenvironment predict non-response to PD-1/PD-L1 inhibitors in metastatic non-small cell lung cancer

Angel Qin
Fatima Lima
Timothy L. Frankel
ResearchOpen Access31 May 2022
Scientific Reports

Volume: 12, P: 1-13
Discriminating pseudoprogression and true progression in diffuse infiltrating glioma using multi-parametric MRI data through deep learning

Joonsang Lee
Nicholas Wang
Arvind Rao
ResearchOpen Access23 Nov 2020
Scientific Reports

Volume: 10, P: 1-10
Molecularly targeted photothermal ablation improves tumor specificity and immune modulation in a rat model of hepatocellular carcinoma

Nina Muñoz et al. present a novel thermal ablation technique, termed molecularly targeted photothermal ablation (MTPA) that generates hyperthermia specifically within tumor tissue in a clinically-relevant rat model of liver cancer. They further show that MTPA modulates the intratumoral immune profile toward stronger tumor immunogenicity while reducing the release of oncogenic cytokines relative to conventional ablation techniques.

Nina M. Muñoz
Crystal Dupuis
Rahul A. Sheth
ResearchOpen Access17 Dec 2020
Communications Biology

Volume: 3, P: 1-10
Tumor core biopsies adequately represent immune microenvironment of high-grade serous carcinoma

Olivia D. Lara
Santhoshi Krishnan
Anil K. Sood
ResearchOpen Access26 Nov 2019
Scientific Reports

Volume: 9, P: 1-10
CSF-1/CSF-1R axis is associated with epithelial/mesenchymal hybrid phenotype in epithelial-like inflammatory breast cancer

Kazuharu Kai
Takayuki Iwamoto
Naoto T. Ueno
ResearchOpen Access21 Jun 2018
Scientific Reports

Volume: 8, P: 1-13
A PET Radiomics Model to Predict Refractory Mediastinal Hodgkin Lymphoma

Sarah A. Milgrom
Hesham Elhalawani
Grace L. Smith
ResearchOpen Access04 Feb 2019
Scientific Reports

Volume: 9, P: 1-8
Goat lung surfactant for treatment of respiratory distress syndrome among preterm neonates: a multi-site randomized non-inferiority trial

Kajal Jain
Sushma Nangia
Ramesh Agarwal
ResearchOpen Access04 Sept 2019
Journal of Perinatology

Volume: 39, P: 3-12
The Paradoxical Relationship between White Matter, Psychopathology and Cognition in Schizophrenia: A Diffusion Tensor and Proton Spectroscopic Imaging Study

Arvind Caprihan
Thomas Jones
Juan R Bustillo
Research18 Mar 2015
Neuropsychopharmacology

Volume: 40, P: 2248-2257
Perturbation of the Glutamate–Glutamine System in Alcohol Dependence and Remission

Robert Thoma
Paul Mullins
Charles Gasparovic
Research09 Mar 2011
Neuropsychopharmacology

Volume: 36, P: 1359-1365
Hypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer

Ashley M. Mello
Tenzin Ngodup
Kyoung Eun Lee
ResearchOpen Access15 Sept 2022
Oncogenesis

Volume: 11, P: 1-9

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