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Advanced filters: Author: Asier Ullate-Agote Clear advanced filters

RANK drives structured intestinal epithelial expansion during pregnancy

The RANK–RANKL pathway drives intestinal epithelial expansion in pregnancy and lactation.

Masahiro Onji
Verena Sigl
Josef M. Penninger
ResearchOpen Access04 Dec 2024
Nature

Volume: 637, P: 156-166
PMEL is involved in snake colour pattern transition from blotches to stripes

Corn snakes are a useful model organism for studying skin pigmentation. Here they characterize the Terrazzo morph and identify the role of PMEL in the patterning of pigmented cells in the skin, explaining how the wild-type blotches change to stripes in Terrazzo.

Athanasia C. Tzika
Asier Ullate-Agote
Maya Kummrow
ResearchOpen Access03 Sept 2024
Nature Communications

Volume: 15, P: 1-13
Single-cell transcriptional profile of CD34+ hematopoietic progenitor cells from del(5q) myelodysplastic syndromes and impact of lenalidomide

The hematopoiesis of patients with del(5q) Myelodysplastic Syndromes is composed of a mixture of cells with and without the deletion. Here, the authors show that del(5q) and non-del(5q) cells share similar transcriptional alterations, with del(5q) cells presenting additional lesions. Moreover, hematological response to lenalidomide is associated with the reversal of some transcriptional lesions in both del(5q) and non-del(5q) cells.

Guillermo Serrano
Nerea Berastegui
Mikel Hernaez
ResearchOpen Access20 Jun 2024
Nature Communications

Volume: 15, P: 1-17

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