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Showing 1–2 of 2 results
Advanced filters: Author: Assa Magassa Clear advanced filters

  • MHC-I antigen presentation pathways are crucial for orchestrating immune responses. Here, the authors introduce a platform for mapping reactive cysteines on MHC-I-bound peptide antigens and discover that these cysteines exhibit varying degrees of reactivity.

    • Chenlu Zhang
    • Chen Zhou
    • Xiaoyu Zhang
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-15

  • Basu et al. report a clustered regularly interspaced short palindromic repeats (CRISPR)-based transcriptional activation screen method for the discovery of E3 ligases suitable for targeted protein degradation and identify the E3 ligase F-box protein 22 capable of promoting ligand-induced degradation of multiple proteins.

    • Ananya A. Basu
    • Chenlu Zhang
    • Xiaoyu Zhang
    Research
    Nature Chemical Biology
    Volume: 20, P: 1608-1616