Nature Search

Population resequencing reveals local adaptation of Arabidopsis lyrata to serpentine soils

Thomas Turner and colleagues have applied next-generation sequencing technology to investigate the genetic basis of adaptive variation. They sequenced pools of DNA from geographically distinct Arabidopsis lyrata populations that are locally adapted to serpentine soils and analyzed 8 million polymorphisms, identifying a putative example of convergent evolution.

Thomas L Turner
Elizabeth C Bourne
Sergey V Nuzhdin
Research24 Jan 2010
Nature Genetics

Volume: 42, P: 260-263
Fiberoptic endoscopic evaluation of swallowing in early-to-advanced stage Huntington’s disease

Antonio Schindler
Nicole Pizzorni
Andrea Ciammola
ResearchOpen Access17 Sept 2020
Scientific Reports

Volume: 10, P: 1-8
Glaucoma and glare

Mehran Hamedani
Barbara Dulley
Ian Murdoch
Research01 Sept 2020
Eye

Volume: 35, P: 1741-1747
Author Correction: The landscape of genomic alterations across childhood cancers

Susanne N. Gröbner
Barbara C. Worst
Stephanie Sungalee
Amendments and Corrections06 Jun 2018
Nature

Volume: 559, P: E10
The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space

In-depth methylation analysis of formalin-fixed paraffin-embedded glioblastoma samples demonstrates heterogeneity between primary and recurring tumors and enables prediction of composition of the tumor microenvironment and insights into progression.

Johanna Klughammer
Barbara Kiesel
Christoph Bock
Research27 Aug 2018
Nature Medicine

Volume: 24, P: 1611-1624
The healing process of diabetic ulcers correlates with changes in the cutaneous microbiota

Emanuele Bruni
Giovanni Luca Scaglione
Cristina Maria Failla
ResearchOpen Access12 Nov 2024
Scientific Reports

Volume: 14, P: 1-12
Multi-omic biomarker panel in pancreatic cyst fluid and serum predicts patients at a high risk of pancreatic cancer development

Laura E. Kane
Gregory S. Mellotte
Stephen G. Maher
ResearchOpen Access02 Jan 2025
Scientific Reports

Volume: 15, P: 1-16
Quantum approximate optimization of non-planar graph problems on a planar superconducting processor

It is hoped that quantum computers may be faster than classical ones at solving optimization problems. Here the authors implement a quantum optimization algorithm over 23 qubits but find more limited performance when an optimization problem structure does not match the underlying hardware.

Matthew P. Harrigan
Kevin J. Sung
Ryan Babbush
Research04 Feb 2021
Nature Physics

Volume: 17, P: 332-336
Enabling FAIR data stewardship in complex international multi-site studies: Data Operations for the Accelerating Medicines Partnership® Schizophrenia Program

Tashrif Billah
Kang Ik K. Cho
Sylvain Bouix
ResearchOpen Access03 Apr 2025
Schizophrenia

Volume: 11, P: 1-11
Assessing and addressing the global state of food production data scarcity

Accurate and timely food production data are needed to promote food security and sustainability, but data scarcity exists across national and international levels. This Review examines data availability and reliability for crops, livestock and aquatic food production and recommends solutions to address data scarcity.

Endalkachew Abebe Kebede
Hanan Abou Ali
Kyle Frankel Davis
Reviews20 Feb 2024
Nature Reviews Earth & Environment

Volume: 5, P: 295-311
Randomized trial of medroxyprogesterone acetate for the prevention of endometrial pathology from adjuvant tamoxifen for breast cancer: SWOG S9630

Ronald K Potkul
Joseph M Unger
Kathy S Albain
ResearchOpen Access10 Aug 2016
npj Breast Cancer

Volume: 2, P: 1-5
Human adaptation: Manage climate-induced resettlement

Governments need research and guidelines to help them to move towns and villages threatened by global warming, argue David López-Carr and Jessica Marter-Kenyon.

David López-Carr
Jessica Marter-Kenyon
Comments & Opinion14 Jan 2015
Nature

Volume: 517, P: 265-267
Photon-assisted tunnelling of zero modes in a Majorana wire

Majorana bound states at the end of nanowires may be used for quantum computation if they can be coupled sufficiently strongly. Here, the Copenhagen lab show strong and tunable coupling, a step along the road towards devices.

David M. T. van Zanten
Deividas Sabonis
Charles M. Marcus
Research13 Apr 2020
Nature Physics

Volume: 16, P: 663-668
Noise-augmented chaotic Ising machines for combinatorial optimization and sampling

Ising Machines are ___domain-specific computers tailored to solve hard combinatorial optimization and probabilistic sampling problems. Here, the authors augment an earlier Ising machine concept that combines billiard dynamics with latches, so-called chaotic bits, with stochasticity, improving performance to rival probabilistic bits.

Kyle Lee
Shuvro Chowdhury
Kerem Y. Camsari
ResearchOpen Access22 Jan 2025
Communications Physics

Volume: 8, P: 1-11
Fabrication of nonplanar tapered fibers to integrate optical and electrical signals for neural interfaces in vivo

Fibertrodes enable the integration of optical and electrical signals in a tapered optical fiber-based implantable neural probe for optogenetic stimulation and simultaneous artifact-free electrophysiological recordings in mice.

Antonio Balena
Marco Bianco
Ferruccio Pisanello
Protocols22 Jan 2025
Nature Protocols

P: 1-42
Estimation of minimal data sets sizes for machine learning predictions in digital mental health interventions

Kirsten Zantvoort
Barbara Nacke
Burkhardt Funk
ResearchOpen Access18 Dec 2024
npj Digital Medicine

Volume: 7, P: 1-10
Calcareous sponges can synthesize their skeleton under short-term ocean acidification

Bárbara Ribeiro
Carolina Lima
Michelle Klautau
ResearchOpen Access25 Apr 2023
Scientific Reports

Volume: 13, P: 1-7
Uncertain future for global sea turtle populations in face of sea level rise

Marga L. Rivas
Emilio Rodríguez-Caballero
Zaida Ortega
ResearchOpen Access20 Apr 2023
Scientific Reports

Volume: 13, P: 1-8
Apocalypse now: Australian bushfires and the future of urban settlements

Barbara Norman
Peter Newman
Will Steffen
ReviewsOpen Access23 Feb 2021
npj Urban Sustainability

Volume: 1, P: 1-9
To do no harm — and the most good — with AI in health care

Drawing from real-life scenarios and insights shared at the RAISE (Responsible AI for Social and Ethical Healthcare) conference, we highlight the critical need for AI in health care (AIH) to primarily benefit patients and address current shortcomings in health care systems such as medical errors and access disparities.

Carey Beth Goldberg
Laura Adams
Jianfei Zhao
Comments & Opinion22 Feb 2024
Nature Medicine

Volume: 30, P: 623-627
The lipid-droplet-associated protein ABHD5 protects the heart through proteolysis of HDAC4

Known as a regulator of lipolysis, ABHD5 is found to also act as a serine protease that cleaves HDAC4 in response to catecholaminergic stimulation, thus resulting in the formation of a polypeptide that protects against metabolic-stress-induced heart failure.

Zegeye H. Jebessa
Kumar D. Shanmukha
Johannes Backs
Research15 Nov 2019
Nature Metabolism

Volume: 1, P: 1157-1167
Megadroughts in the Common Era and the Anthropocene

Megadroughts can be defined as persistent, multi-year droughts that are exceptional compared with other regional events during the Common Era. This Review discusses palaeo reconstructions of megadroughts over the past 2,000 years, and outlines the impact of anthropogenic forcing on the severity and frequency of observed and projected events.

Benjamin I. Cook
Jason E. Smerdon
Erika K. Wise
Reviews04 Oct 2022
Nature Reviews Earth & Environment

Volume: 3, P: 741-757
Association of perinatal sentinel events, placental pathology and cerebral MRI in neonates with hypoxic-ischemic encephalopathy receiving therapeutic hypothermia

Lia Hellwig
Muriel Brada
Beate Grass
ResearchOpen Access28 Feb 2022
Journal of Perinatology

Volume: 42, P: 885-891
Genetic structure and divergence of marginal populations of black poplar (Populus nigra L.) in Poland

Weronika Barbara Żukowska
Andrzej Lewandowski
ResearchOpen Access23 Jan 2025
Scientific Reports

Volume: 15, P: 1-14
Artificial intelligence for image recognition in diagnosing oral and oropharyngeal cancer and leukoplakia

Benedikt Schmidl
Tobias Hütten
Markus Wirth
ResearchOpen Access29 Jan 2025
Scientific Reports

Volume: 15, P: 1-10
Results and lessons learned from the sbv IMPROVER metagenomics diagnostics for inflammatory bowel disease challenge

Lusine Khachatryan
Yang Xiang
Carine Poussin
ResearchOpen Access18 Apr 2023
Scientific Reports

Volume: 13, P: 1-19
Spatial attention and representation of time intervals in childhood

Barbara Magnani
Alessandro Musetti
Francesca Frassinetti
ResearchOpen Access11 Sept 2020
Scientific Reports

Volume: 10, P: 1-8
Non-dipping pattern in early-stage diabetes: association with glycemic profile and hemodynamic parameters

Barbara Nikolaidou
Panagiota Anyfanti
Eugenia Gkaliagkousi
Research16 Aug 2021
Journal of Human Hypertension

Volume: 36, P: 805-810
A community computational challenge to predict the activity of pairs of compounds

A community computational challenge generates algorithms to predict activity of drug combinations.

Mukesh Bansal
Jichen Yang
Andrea Califano
Research17 Nov 2014
Nature Biotechnology

Volume: 32, P: 1213-1222
Classifying the evolutionary and ecological features of neoplasms

Based on a consensus conference of experts in the evolution and ecology of cancer, this article proposes a framework for classifying tumours that includes four evolutionary and ecological processes: neoplastic cell diversity and changes over time in that diversity, hazards to cell survival and available resources.

Carlo C. Maley
Athena Aktipis
Darryl Shibata
ReviewsOpen Access15 Sept 2017
Nature Reviews Cancer

Volume: 17, P: 605-619
Evaluating survival outcomes and treatment recommendations in resectable gastric cancer

Saad Sabbagh
Iktej Singh Jabbal
Arun Nagarajan
ResearchOpen Access22 Jan 2025
Scientific Reports

Volume: 15, P: 1-11
Hematopoietic stem cell transplantation for isolated extramedullary relapse of acute lymphoblastic leukemia in children

Maria Gabelli
Marco Zecca
Franco Locatelli
Research13 Jun 2018
Bone Marrow Transplantation

Volume: 54, P: 275-283
Clinical Features of Neuroblastoma with 11q Deletion: An Increase in Relapse Probabilities in Localized and 4S Stages

Antonio Juan Ribelles
Sandra Barberá
Victoria Castel
ResearchOpen Access24 Sept 2019
Scientific Reports

Volume: 9, P: 1-9
Participant-reported priorities and preferences for developing a home-based physical activity telemonitoring program for persons with tetraplegia: a qualitative analysis

Renee Pekmezaris
Andrzej Kozikowski
Ona Bloom
ResearchOpen Access16 May 2019
Spinal Cord Series and Cases

Volume: 5, P: 1-7
South America's earliest rodent and recognition of a new interval of mammalian evolution

André R. Wyss
John J. Flynn
Malcolm C. McKenna
Research30 Sept 1993
Nature

Volume: 365, P: 434-437
Disease severity and symptoms among patients receiving monotherapy for COPD

Mark T Dransfield
William Bailey
Barbara Yawn
Research30 Sept 2010
Primary Care Respiratory Journal

Volume: 20, P: 46-53
Nausea in the peri-traumatic period is associated with prospective risk for PTSD symptom development

Vasiliki Michopoulos
Jessica Maples-Keller
Kerry J. Ressler
Research21 Nov 2018
Neuropsychopharmacology

Volume: 44, P: 668-673
Ocean community warming responses explained by thermal affinities and temperature gradients

The ways in which ocean communities respond to warming are related to their composition. The variety of thermal affinities and thermal ranges of individual species, along with vertical temperature gradients, shape community response and allow the prediction of regional responses to warming.

Michael T. Burrows
Amanda E. Bates
Elvira S. Poloczanska
Research25 Nov 2019
Nature Climate Change

Volume: 9, P: 959-963
Systematic assessment of long-read RNA-seq methods for transcript identification and quantification

This Registered Report presents the results of the Long-read RNA-Seq Genome Annotation Assessment Project, which is a community effort for benchmarking long-read methods for transcriptome analyses, including transcript isoform detection, quantification and de novo transcript detection.

Francisco J. Pardo-Palacios
Dingjie Wang
Angela N. Brooks
ResearchOpen Access07 Jun 2024
Nature Methods

Volume: 21, P: 1349-1363
DO NEONATOLOGISTS AND NURSES DIFFER IN THEIR PREFERENCES FOR OUTCOMES OF NEONATAL INTENSIVE CARE? † 1652

Saroj Saigal
David H Feeny
Elizabeth A Burrows
Research01 Apr 1996
Pediatric Research

Volume: 39, P: 278
Killer lymphocytes use granulysin, perforin and granzymes to kill intracellular parasites

Judy Lieberman and colleagues show that intracellular parasites are eradicated by lymphocyte delivery of cytotoxic granule contents—perforin, granulysin and granzymes—into infected cells.

Farokh Dotiwala
Sachin Mulik
Judy Lieberman
Research11 Jan 2016
Nature Medicine

Volume: 22, P: 210-216
China’s lust for jaguar fangs imperils big cats

Wildlife traffickers in South America seek body parts from protected species to satisfy demand in Asia.

Barbara Fraser
News23 Feb 2018
Nature

Volume: 555, P: 13-14
Active medulloblastoma enhancers reveal subgroup-specific cellular origins

Genomic studies of the paediatric brain tumour medulloblastoma have revealed four clinically distinct molecular subgroups; here active gene regulatory elements in 28 primary medulloblastoma tissues are mapped to reveal differentially regulated enhancers across the different subgroups, allowing insights into the transcription factors that characterize subgroup divergence and the cellular origin of the poorly characterized Group 3 and 4 subgroups.

Charles Y. Lin
Serap Erkek
Paul A. Northcott
Research27 Jan 2016
Nature

Volume: 530, P: 57-62
Bright spots among the world’s coral reefs

Data from over 2,500 reefs worldwide is used to identify 15 bright spots—sites where reef biomass is significantly higher than expected—and surveys of local experts in these areas suggest that strong sociocultural institutions and high levels of local engagement are among the factors supporting higher fish biomass.

Joshua E. Cinner
Cindy Huchery
David Mouillot
Research15 Jun 2016
Nature

Volume: 535, P: 416-419
Accuracy of ancestral state reconstruction for non-neutral traits

Barbara R. Holland
Saan Ketelaar-Jones
Gregory J. Jordan
ResearchOpen Access06 May 2020
Scientific Reports

Volume: 10, P: 1-10
Engineering the next generation

A silicon-based membrane for fuel cells offers significant advantages over Nafion-based membranes.

Steven K. Buratto
News & Views01 Mar 2010
Nature Nanotechnology

Volume: 5, P: 176
Measure methane to quantify the oil spill

Plumes of dissolved gas could be used to determine how much oil has leaked into the Gulf of Mexico, says David Valentine — if the studies are done soon.

David Valentine
Comments & Opinion26 May 2010
Nature

Volume: 465, P: 421
Ozone depletion, ultraviolet radiation, climate change and prospects for a sustainable future

Ozone depletion has altered conditions at the Earth’s surface and interacts with climate change. This Review assesses the effects on humans and ecosystems, including implications for food and water security, and the mitigating and ongoing influence of the Montreal Protocol.

Paul W. Barnes
Craig E. Williamson
Richard G. Zepp
Reviews24 Jun 2019
Nature Sustainability

Volume: 2, P: 569-579
MRI data-driven clustering reveals different subtypes of Dementia with Lewy bodies

Anna Inguanzo
Konstantinos Poulakis
Daniel Ferreira
ResearchOpen Access20 Jan 2023
npj Parkinson's Disease

Volume: 9, P: 1-7
Swarm of lightsail nanosatellites for Solar System exploration

Giovanni Santi
Alain J. Corso
Maria G. Pelizzo
ResearchOpen Access09 Nov 2023
Scientific Reports

Volume: 13, P: 1-16

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