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Modulation of glymphatic system by visual circuit activation alleviates memory impairment and apathy in a mouse model of Alzheimer’s disease

Treatments for Alzheimer’s disease (AD) remain limited. Here, the authors show that 40 hertz blue light activates a visual circuit to boost glymphatic drainage, and enhances memory, motivation, and anti-Aβ therapy efficacy in a mouse model of AD.

Wen Wu
Yubai Zhao
Wei-Jye Lin
ResearchOpen Access02 Jan 2025
Nature Communications

Volume: 16, P: 1-20
Correction: Corrigendum: Nuclear BK channels regulate gene expression via the control of nuclear calcium signaling

Boxing Li
Wei Jie
Tian-Ming Gao
Amendments and Corrections21 Nov 2014
Nature Neuroscience

Volume: 17, P: 1841
Electrically tunable two-dimensional heterojunctions for miniaturized near-infrared spectrometers

Miniaturized infrared spectrometers are required for imaging and remote sensing applications, but they are usually characterized by a cm-scale footprint. Here, the authors report the realization of near-infrared spectrometers based on Au-atom-intercalated ReS₂/WSe₂ heterostructures with an active footprint < 10 μm and electrically tunable photoresponse.

Wenjie Deng
Zilong Zheng
Yongzhe Zhang
ResearchOpen Access08 Aug 2022
Nature Communications

Volume: 13, P: 1-10
Long-term outcomes of Allium ureteral stent as a treatment for ureteral obstruction

Boxing Su
Weiguo Hu
Jianxing Li
ResearchOpen Access20 Sept 2024
Scientific Reports

Volume: 14, P: 1-7
Hidden delays of climate mitigation benefits in the race for electric vehicle deployment

The climate benefits of battery electric vehicles relative to internal combustion engine vehicles are favorable but usually delayed. The authors show the delay threshold in China and call for more attention to the temporal characteristics of climate benefits.

Yue Ren
Xin Sun
Xinzhu Zheng
ResearchOpen Access31 May 2023
Nature Communications

Volume: 14, P: 1-12
Nuclear BK channels regulate gene expression via the control of nuclear calcium signaling

Nuclear calcium levels affect gene expression, but little is known about how they are regulated. The authors show that large-conductance calcium-activated potassium (BK) channels are present on the nuclear envelope in rodent hippocampal neurons. Blockade of nuclear BK channels revealed that they regulate nucleoplasmic Ca²⁺, gene expression and dendritic arborization.

Boxing Li
Wei Jie
Tian-Ming Gao
Research22 Jun 2014
Nature Neuroscience

Volume: 17, P: 1055-1063

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Modulation of glymphatic system by visual circuit activation alleviates memory impairment and apathy in a mouse model of Alzheimer’s disease

Correction: Corrigendum: Nuclear BK channels regulate gene expression via the control of nuclear calcium signaling

Electrically tunable two-dimensional heterojunctions for miniaturized near-infrared spectrometers

Long-term outcomes of Allium ureteral stent as a treatment for ureteral obstruction

Hidden delays of climate mitigation benefits in the race for electric vehicle deployment

Nuclear BK channels regulate gene expression via the control of nuclear calcium signaling

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