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Showing 1–5 of 5 results
Advanced filters: Author: Brinda Vijaykumar Clear advanced filters

  • Differentiating neutrophil functional states is difficult. Here the authors show, using single cell RNA-sequencing and trajectory analyses, that mouse neutrophils can be presented as a transcriptome continuum rather than discrete subsets, but are affected by inflammation to express distinct transcriptional states.

    • Ricardo Grieshaber-Bouyer
    • Felix A. Radtke
    • Hideyuki Yoshida
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-21

  • Helper T cell subsets are characterized functionally by the cytokines they produce. Benoist and colleagues demonstrate that in vivo helper T cells do not manifest as discrete helper subsets but rather form a continuum shaped by microbial exposure.

    • Evgeny Kiner
    • Elijah Willie
    • Hideyuki Yoshida
    Research
    Nature Immunology
    Volume: 22, P: 216-228

  • Nature Immunology’s 20th anniversary is a good opportunity to reminisce about the ImmGen collective endeavor — its goals, successes and horror stories — and the group’s exploration of various modes of scientific publishing.

    • Stephanie Vargas Aguilar
    • Oscar Aguilar
    • Caroline Ziemkiewicz
    Comments & Opinion
    Nature Immunology
    Volume: 21, P: 700-703

  • Brown and colleagues generated an atlas of miRNA expression profiles from primary mouse immune cell populations and connected these signatures with ATAC–seq, ChIP–seq and nascent RNA profiles to establish a map of miRNA promoter and enhancer usage in immune cells.

    • Samuel A. Rose
    • Aleksandra Wroblewska
    • Aldrin Yim
    Research
    Nature Immunology
    Volume: 22, P: 914-927