Nature Search

Shared genetic architecture of posttraumatic stress disorder with cardiovascular imaging, risk, and diagnoses

Study shows PTSD predisposition shares distinct genes and genomic regions with several cardiovascular conditions. Here the findings reveal neuronal, immune, and metabolic pathways, and repurposed drug targets that further the understanding of the comorbidity.

Jie Shen
Wander Valentim
Gita A. Pathak
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-17
A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome

Richard Wooster
Jonathan Mangion
Michael R. Stratton
Research01 Oct 1992
Nature Genetics

Volume: 2, P: 132-134
Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q

Michael R. Stratton
Deborah Ford
David E. Goldgar
Research01 May 1994
Nature Genetics

Volume: 7, P: 103-107
Plant diversity dynamics over space and time in a warming Arctic

Warming temperatures and interactions between plants are the main drivers of changes in Arctic plant communities in response to climate change, and there is no evidence of overall biotic homogenization.

Mariana García Criado
Isla H. Myers-Smith
Mark Vellend
ResearchOpen Access30 Apr 2025
Nature

Volume: 642, P: 653-661
Fault Lines in the Atlantic

WM. S. BRUCE
Research14 May 1908
Nature

Volume: 78, P: 31
Toxicity of Poly I.Poly C for Rabbit Eyes

H. BRUCE OSTLER
JANG O. OH
W. LAURENCE BURT
Research24 Oct 1970
Nature

Volume: 228, P: 362-364
Testis-derived Sertoli cells survive and provide localized immunoprotection for xenografts in rat brain

Paul R. Sanberg
Cesario V. Borlongan
Don F. Cameron
Research01 Dec 1996
Nature Biotechnology

Volume: 14, P: 1692-1695
Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder

Multi-ancestry genome-wide analyses identify 95 loci associated with post-traumatic stress disorder and implicate candidate genes, pathways and neurobiological systems underlying its pathophysiology.

Caroline M. Nievergelt
Adam X. Maihofer
Karestan C. Koenen
Research18 Apr 2024
Nature Genetics

Volume: 56, P: 792-808
Aptamer-based multiplexed proteomic technology for biomarker discovery

Larry Gold
Deborah Ayers
Dom Zichi
ResearchOpen Access14 Jun 2010
Nature Precedings

P: 1
Innovation exceeds fear of climate change in Greenland

Greenland is central to climate research and research now shows that Greenlanders are far more aware of a rapidly changing Arctic climate than of the underlying global causes. However, their willingness to harness new opportunities exceeds fear of climate change’s consequences.

Bruce C. Forbes
Florian Stammler
News & Views26 Jun 2023
Nature Climate Change

Volume: 13, P: 603-605
Novel genetic loci associated with hippocampal volume

The hippocampus in mammalian brain varies in size across individuals. Here, Hibar and colleagues perform a genome-wide association meta-analysis to find six genetic loci with significant association to hippocampus volume.

Derrek P. Hibar
Hieab H. H. Adams
M. Arfan Ikram
ResearchOpen Access18 Jan 2017
Nature Communications

Volume: 8, P: 1-12
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

Paul R Burton
David G Clayton
Matthew A Brown
Research21 Oct 2007
Nature Genetics

Volume: 39, P: 1329-1337
Summer warming explains widespread but not uniform greening in the Arctic tundra biome

Satellites provide clear evidence of greening trends in the Arctic, but high-resolution pan-Arctic quantification of these trends is lacking. Here the authors analyse high-resolution Landsat data to show widespread greening in the Arctic, and find that greening trends are linked to summer warming overall but not always locally.

Logan T. Berner
Richard Massey
Scott J. Goetz
ResearchOpen Access22 Sept 2020
Nature Communications

Volume: 11, P: 1-12
International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

Post-traumatic stress disorder (PTSD) is a common mental health problem. Here, the authors report a GWAS from the Psychiatric Genomics Consortium in which they identify two risk loci in European ancestry and one locus in African ancestry individuals and find that PTSD is genetically correlated with several other psychiatric traits.

Caroline M. Nievergelt
Adam X. Maihofer
Karestan C. Koenen
ResearchOpen Access08 Oct 2019
Nature Communications

Volume: 10, P: 1-16
A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer

Philip Stephens
Sarah Edkins
Richard Wooster
Research22 May 2005
Nature Genetics

Volume: 37, P: 590-592
Plant traits poorly predict winner and loser shrub species in a warming tundra biome

Functional trait data could guide predictions of species responses to environmental change. Here, the authors show that winner and loser shrub species in the warming tundra biome overlap in trait space and may therefore be difficult to predict based on commonly measured traits.

Mariana García Criado
Isla H. Myers-Smith
Anna-Maria Virkkala
ResearchOpen Access28 Jun 2023
Nature Communications

Volume: 14, P: 1-17
New climate models reveal faster and larger increases in Arctic precipitation than previously projected

The Arctic warms faster than other areas of the planet, which also influences precipitation. Here, the authors show that the latest CMIP6 model ensemble shows a faster Arctic warming and sea-ice loss, causing an earlier transition from a snow- to a rain-dominated Arctic than previously thought.

Michelle R. McCrystall
Julienne Stroeve
James A. Screen
ResearchOpen Access30 Nov 2021
Nature Communications

Volume: 12, P: 1-12
Climate sensitivity of shrub growth across the tundra biome

Rapid climate warming has been linked to increasing shrub dominance in the Arctic tundra. Research now shows that climate–shrub growth relationships vary spatially and according to site characteristics such as soil moisture and shrub height.

Isla H. Myers-Smith
Sarah C. Elmendorf
Mark Vellend
Research06 Jul 2015
Nature Climate Change

Volume: 5, P: 887-891
Eurasian Arctic greening reveals teleconnections and the potential for structurally novel ecosystems

Increasing shrub cover on Arctic tundra is linked to climate warming, which is partially amplified by sea ice feedbacks, but the nature of these interactions remains poorly understood. Now research indicates that tundra plant productivity in late spring relates to sea-ice-driven temperature amplification but that the growing season peak is more closely associated with persistent large-scale atmospheric circulation patterns.

Marc Macias-Fauria
Bruce C. Forbes
Timo Kumpula
Research03 Jun 2012
Nature Climate Change

Volume: 2, P: 613-618
Plant functional trait change across a warming tundra biome

Analyses of the relationships between temperature, moisture and seven key plant functional traits across the tundra and over time show that community height increased with warming across all sites, whereas other traits lagged behind predicted rates of change.

Anne D. Bjorkman
Isla H. Myers-Smith
Evan Weiher
Research26 Sept 2018
Nature

Volume: 562, P: 57-62
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Genome-wide association study identifies novel breast cancer susceptibility loci

Previous work has identified several genes where mutations lead to breast cancer, but other genetic and environmental factors must still be accounted for. A large study of genetic association with breast cancer points to four novel genes and many more genetic markers that should be pursued for their link to cancer susceptibility.

Douglas F. Easton
Karen A. Pooley
Bruce A. J. Ponder
Research28 Jun 2007
Nature

Volume: 447, P: 1087-1093
Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

Over 170 susceptibility loci have been identified by genome-wide association studies in breast cancer. Here, the authors interrogated the role of risk-associated variants from non-breast tissue, and using expression quantitative trait loci, identify potential target genes of known breast cancer susceptibility variants, as well as 11 regions not previously known to be associated with breast cancer risk.

Manuel A. Ferreira
Eric R. Gamazon
Georgia Chenevix-Trench
ResearchOpen Access15 Apr 2019
Nature Communications

Volume: 10, P: 1-18
Possible vertebral brucellosis infection in a Neanderthal

Bruce Rothschild
Martin Haeusler
ResearchOpen Access06 Oct 2021
Scientific Reports

Volume: 11, P: 1-9
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

An exciting genome-wide association study in the British population for seven common diseases. This analysis confirms previously identified loci and provides strong evidence for many novel disease susceptibility loci.

Paul R. Burton
David G. Clayton
Jane Worthington
Research07 Jun 2007
Nature

Volume: 447, P: 661-678
Host shift to an invasive plant triggers rapid animal hybrid speciation

Dietmar Schwarz
Benjamin M. Matta
Bruce A. McPheron
Research28 Jul 2005
Nature

Volume: 436, P: 546-549
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

Copy number variants (CNVs) account for a major proportion of human genetic diversity and may contribute to genetic susceptibility to disease. Here, a large, genome-wide study of association between common CNVs and eight common human diseases is presented. The study provides a wealth of technical insights that will inform future study design and analysis. The results also indicate that common CNVs that can be 'typed' on existing platforms are unlikely to contribute much to the genetic basis of common diseases.

Nick Craddock
Matthew E. Hurles
Peter Donnelly
Research01 Apr 2010
Nature

Volume: 464, P: 713-720
Reducing the energy cost of human walking using an unpowered exoskeleton

The attachment of a simple, unpowered, mechanical exoskeleton to the foot and ankle results in a net saving of 7% of the metabolic energy expended in human walking.

Steven H. Collins
M. Bruce Wiggin
Gregory S. Sawicki
Research01 Apr 2015
Nature

Volume: 522, P: 212-215
Possible bite-induced abscess and osteomyelitis in Lufengosaurus (Dinosauria: sauropodomorph) from the Lower Jurassic of the Yimen Basin, China

Lida Xing
Bruce M. Rothschild
Hao Ran
ResearchOpen Access22 Mar 2018
Scientific Reports

Volume: 8, P: 1-8
Complexity revealed in the greening of the Arctic

As tundra ecosystems respond to rapid Arctic warming, satellite records suggest a widespread greening. This Perspective highlights the challenges of interpreting complex Arctic greening trends and provides direction for future research by combining ecological and remote sensing approaches.

Isla H. Myers-Smith
Jeffrey T. Kerby
Sonja Wipf
Reviews31 Jan 2020
Nature Climate Change

Volume: 10, P: 106-117
Increased liver AGEs induce hepatic injury mediated through an OST48 pathway

Aowen Zhuang
Felicia YT. Yap
Josephine M. Forbes
ResearchOpen Access25 Sept 2017
Scientific Reports

Volume: 7, P: 1-12
Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

New methods and larger sample groups are used to precisely determine the alleles in the HLA complex which contribute susceptibility to type 1 diabetes.

Sergey Nejentsev
Joanna M. M. Howson
Jane Worthington
Research14 Nov 2007
Nature

Volume: 450, P: 887-892
Author Correction: Supporting US public health experts

Ron Cohen
Cedric Francois
Sandy Zweifach
Amendments and Corrections17 Dec 2020
Nature Biotechnology

Volume: 39, P: 115
Supporting US public health experts

Ron Cohen
Cedric Francois
Sandy Zweifach
Correspondence25 Nov 2020
Nature Biotechnology

Volume: 38, P: 1381-1384
Cortical connectomic mediations on gamma band synchronization in schizophrenia

Xiaoming Du
Stephanie Hare
L. Elliot Hong
ResearchOpen Access19 Jan 2023
Translational Psychiatry

Volume: 13, P: 1-10
Disentangling the coupling between sea ice and tundra productivity in Svalbard

Marc Macias-Fauria
Stein Rune Karlsen
Bruce C. Forbes
ResearchOpen Access17 Aug 2017
Scientific Reports

Volume: 7, P: 1-10
Dinosaur senescence: a hadrosauroid with age-related diseases brings a new perspective of “old” dinosaurs

Justyna Słowiak
Tomasz Szczygielski
Dawid Surmik
ResearchOpen Access11 Jun 2021
Scientific Reports

Volume: 11, P: 1-12
Potential causal association between gut microbiome and posttraumatic stress disorder

Qiang He
Wenjing Wang
Karestan C. Koenen
ResearchOpen Access31 Jan 2024
Translational Psychiatry

Volume: 14, P: 1-12
Suggested Case of Langerhans Cell Histiocytosis in a Cretaceous dinosaur

Bruce M. Rothschild
Darren Tanke
Hila May
ResearchOpen Access10 Feb 2020
Scientific Reports

Volume: 10, P: 1-10
The Arctic Plant Aboveground Biomass Synthesis Dataset

Logan T. Berner
Kathleen M. Orndahl
Scott J. Goetz
ResearchOpen Access20 Mar 2024
Scientific Data

Volume: 11, P: 1-13
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

Alberto Romagnoni
Simon Jégou
Pamela Whittaker
ResearchOpen Access17 Jul 2019
Scientific Reports

Volume: 9, P: 1-18
HIT-COVID, a global database tracking public health interventions to COVID-19

Qulu Zheng
Forrest K. Jones
Navdeep Singh
ResearchOpen Access27 Aug 2020
Scientific Data

Volume: 7, P: 1-8

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