Nature Search

Timing of unsaturated fat intake improves insulin sensitivity via the gut microbiota-bile acid axis: a randomized controlled trial

Here, Ying Li et al. present the results of a randomized controlled feeding trial in prediabetes participants, finding that advancing timing of unsaturated fat (USFA) intake improves insulin sensitivity through the gut microbiome and bile acid metabolism, regardless of USFA type.

Chunbo Wei
Xiaoqing Xu
Ying Li
ResearchOpen Access06 May 2025
Nature Communications

Volume: 16, P: 1-16
Multidentate ether modifies solvation structure in nonflammable phosphate electrolytes for wide-temperature lithium-ion batteries

Diethyl ethylphosphonate (DEEP) is a promising candidate for developing non- flammable electrolytes for wide-temperature application in Li-ion batteries, but low compatibility with graphite electrodes and slow ionic transport hinder its implementation. Here, the authors show that incorporating diethylene glycol dimethyl ether into a DEEP-based electrolyte enhances ion transport and improves low-temperature performance in graphite-based cells.

Xiankun Yang
Ziqi Zeng
Jia Xie
ResearchOpen Access07 Jun 2025
Communications Chemistry

Volume: 8, P: 1-8
Robust mucosal SARS-CoV-2-specific T cells effectively combat COVID-19 and establish polyfunctional resident memory in patient lungs

The authors show that SARS-CoV-2-specific T cells in the lung are key to fighting infection and persist after viral clearance, contributing to long-term immunity and protection.

Airu Zhu
Zhao Chen
Jincun Zhao
ResearchOpen Access28 Jan 2025
Nature Immunology

Volume: 26, P: 459-472
Global marine microbial diversity and its potential in bioprospecting

Analysis of 43,191 genomes obtained from publicly available marine bacterial and archaeal metagenome data provides insights into marine bacterial evolution, CRISPR–Cas defence and antibiotic resistance genes, and demonstrates the potential of marine metagenomes for biotechnological applications.

Jianwei Chen
Yangyang Jia
Guangyi Fan
ResearchOpen Access04 Sept 2024
Nature

Volume: 633, P: 371-379
Genetic compensation response contributes to Pleurodeles waltl limb regeneration

Binxu Yin
Changhao Yu
Heng Wang
ResearchOpen Access31 May 2025
npj Regenerative Medicine

Volume: 10, P: 1-6
Glycosylase-based base editors for efficient T-to-G and C-to-G editing in mammalian cells

Base editors lacking a deaminase improve thymine and cytosine conversion.

Lijun Ye
Dongdong Zhao
Changhao Bi
Research02 Jan 2024
Nature Biotechnology

Volume: 42, P: 1538-1547
Global riverine land-to-ocean carbon export constrained by observations and multi-model assessment

Global riverine carbon export to the ocean may exceed previous estimates, underscoring the important role of riverine carbon to the carbon budget, according to a multi-model ensemble assessment constrained by a global dataset.

Maodian Liu
Peter A. Raymond
Pierre Regnier
Research05 Sept 2024
Nature Geoscience

Volume: 17, P: 896-904
Potent prophylactic cancer vaccines harnessing surface antigens shared by tumour cells and induced pluripotent stem cells

A prophylactic cancer vaccine consisting of commercial adjuvants wrapped by membranes from pluripotent stem cells inhibited tumour progression in mice, owing to shared antigens between tumour membranes and the pluripotent stem cell membranes.

Nan Li
Hao Qin
Ruifang Zhao
Research27 Dec 2024
Nature Biomedical Engineering

Volume: 9, P: 215-233
Enhancement of a prime editing system via optimal recruitment of the pioneer transcription factor P65

Prime editing represents a great advance to the genome editing field but is currently limited by the editing efficiency. Here the authors look to improve the efficiency by recruiting target proteins and show that the transcription factor P65 could enhance the desired editing outcomes at different gene loci.

Ronghao Chen
Yu Cao
Xueli Zhang
ResearchOpen Access17 Jan 2023
Nature Communications

Volume: 14, P: 1-8
Concentration polarization induced phase rigidification in ultralow salt colloid chemistry to stabilize cryogenic Zn batteries

Here, the authors design a “beyond aqueous” colloidal electrolyte with ultralow salt concentration and inherent low freezing point and investigate its colloidal behaviors and underlying mechanistic principles to stabilize cryogenic Zn metal battery.

Baojiu Hao
Jinqiu Zhou
Tao Qian
ResearchOpen Access01 Nov 2024
Nature Communications

Volume: 15, P: 1-16
Deciphering the phase transition-induced ultrahigh piezoresponse in (K,Na)NbO₃-based piezoceramics

Functional oxides with coexisting states of comparable energy typically exhibit extraordinary responses to external stimuli. Here, the authors demonstrate that coexisting phase structures provide large electric field-triggered volume change.

Mao-Hua Zhang
Chen Shen
Manuel Hinterstein
ResearchOpen Access15 Jun 2022
Nature Communications

Volume: 13, P: 1-10
HMGN1 enhances CRISPR-directed dual-function A-to-G and C-to-G base editing

Limited work has been done on concurrent C-to-G and A-to-G base editing. Here the authors test how a number of chromatin-associated factors affect base editing and show that HMGN1 enhanced the efficiency; by fusing HMGN1 to GBE and ABE they develop a CRISPR-based dual-function A-to-G and C-to-G base editor (GGBE).

Chao Yang
Zhenzhen Ma
Xueli Zhang
ResearchOpen Access27 Apr 2023
Nature Communications

Volume: 14, P: 1-12
Ultrastable electrocatalytic seawater splitting at ampere-level current density

Renewable-energy-powered electrolysis of seawater provides a sustainable means of mass production of hydrogen, a critical fuel for tomorrow’s energy mix. Here the layered double hydroxide (LDH) electrocatalyst design enables ultrastable seawater splitting at industry-compatible current densities.

Rongli Fan
Changhao Liu
Zhigang Zou
Research09 Feb 2024
Nature Sustainability

Volume: 7, P: 158-167
RNA helicase Brr2a promotes miRNA biogenesis by properly remodelling secondary structure of pri-miRNAs

RNA secondary structure is a new regulatory layer of transcript fates. Here, Li et al. find that plant RNA helicase Brr2a, acting beyond its canonical role in spliceosome, can optimize secondary structure of pri-miRNAs to promote miRNA production.

Xindi Li
Songxiao Zhong
Xiuren Zhang
Research13 Sept 2024
Nature Plants

Volume: 10, P: 1532-1547
Long-term durability of metastable β-Fe₂O₃ photoanodes in highly corrosive seawater

Achieving long-term stable photoelectrochemical water decomposition in highly corrosive seawater remains a challenge. Here, the authors report a strategy for enhancing metal-oxygen interaction to achieve high stability of metastable β-Fe₂O₃ photoelectrochemical seawater splitting.

Changhao Liu
Ningsi Zhang
Zhigang Zou
ResearchOpen Access17 Jul 2023
Nature Communications

Volume: 14, P: 1-8
LNMAT1 promotes lymphatic metastasis of bladder cancer via CCL2 dependent macrophage recruitment

Mechanism of lymph node (LN) metastasis induced by tumor associated macrophages (TAMs) remains unclear. Here they demonstrate that a long noncoding RNA LNMAT1 promotes LN metastasis of bladder cancer via recruitment of TAMs through epigenetic regulation of CCL2 expression.

Changhao Chen
Wang He
Tianxin Lin
ResearchOpen Access20 Sept 2018
Nature Communications

Volume: 9, P: 1-18
STING aggravates ferroptosis-dependent myocardial ischemia-reperfusion injury by targeting GPX4 for autophagic degradation

Xiaohong Wang
Tao Chen
Cheng Zhang
ResearchOpen Access25 Apr 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-17
Compact all-fiber quantum-inspired LiDAR with over 100 dB noise rejection and single photon sensitivity

LiDARs exploiting quantum correlations provide enhancement in noise resilience and sensitivity, but high-power classical sources offer much higher operating distances. Here, the authors show how to exploit high power classical time-frequency correlations to keep the best of both worlds.

Han Liu
Changhao Qin
Amr S. Helmy
ResearchOpen Access02 Sept 2023
Nature Communications

Volume: 14, P: 1-8
H3.1K27me1 loss confers Arabidopsis resistance to Geminivirus by sequestering DNA repair proteins onto host genome

Geminiviruses hijack the host DNA repairing proteins for their amplification. The authors report that Arabidopsis loses H3.1K27me1, a protector of genome stability, but gains resistance to geminivirus infection via retaining key factors like RAD51.

Zhen Wang
Claudia M. Castillo-González
Xiuren Zhang
ResearchOpen Access18 Nov 2023
Nature Communications

Volume: 14, P: 1-20
Parallel degradome-seq and DMS-MaPseq substantially revise the miRNA biogenesis atlas in Arabidopsis

Parallel degradome sequencing and DMS-MaPseq pinpoint the first cleavage sites on bona fide pri-miRNAs, decode their in vivo structure and provide better interpretation of the cleavage modes and impact of DCL1 cofactors in the process in Arabidopsis.

Xingxing Yan
Changhao Li
Xiuren Zhang
Research25 Jun 2024
Nature Plants

Volume: 10, P: 1126-1143
Rapid and ultrasensitive electromechanical detection of ions, biomolecules and SARS-CoV-2 RNA in unamplified samples

A self-assembled DNA-based system immobilized on a liquid-gated graphene field-effect transistor can electromechanically detect ultralow levels of unamplified ions, nucleic acids, small molecules and proteins in biofluids.

Liqian Wang
Xuejun Wang
Dacheng Wei
Research07 Feb 2022
Nature Biomedical Engineering

Volume: 6, P: 276-285
Platinum single-atom catalyst coupled with transition metal/metal oxide heterostructure for accelerating alkaline hydrogen evolution reaction

While H₂ evolution from water may represent a renewable energy source, there is a strong need to improve catalytic efficiencies while maximizing materials utilization. Here, authors examine single-atom Pt on nickel-based heterostructures as highly active electrocatalysts for alkaline H₂ evolution.

Kai Ling Zhou
Zelin Wang
Hui Yan
ResearchOpen Access18 Jun 2021
Nature Communications

Volume: 12, P: 1-10
ycf1, the most promising plastid DNA barcode of land plants

Wenpan Dong
Chao Xu
Shiliang Zhou
ResearchOpen Access12 Feb 2015
Scientific Reports

Volume: 5, P: 1-5
Spontaneous Growth and Chemical Reduction Ability of Ge Nanoparticles

Jun Liu
Changhao Liang
Guosheng Shao
ResearchOpen Access29 Apr 2013
Scientific Reports

Volume: 3, P: 1-5
Author Correction: Heat acclimation in mice requires preoptic BDNF neurons and postsynaptic potentiation

Baoting Chen
Cuicui Gao
Wei L. Shen
Amendments and CorrectionsOpen Access24 Jan 2025
Cell Research

Volume: 35, P: 228
Prediction of formation abrasiveness under the action of a PDC bit based on the fractal dimension of a rock surface

Changhao Wang
Shaojie Li
Zhaoyi Liu
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-13
CLIC3 interacts with NAT10 to inhibit N4-acetylcytidine modification of p21 mRNA and promote bladder cancer progression

Yujun Shuai
Hui Zhang
Guosong Jiang
ResearchOpen Access05 Jan 2024
Cell Death & Disease

Volume: 15, P: 1-14
The long non-coding RNA FOXD2-AS1 promotes bladder cancer progression and recurrence through a positive feedback loop with Akt and E2F1

Feng Su
Wang He
Chun Jiang
ResearchOpen Access14 Feb 2018
Cell Death & Disease

Volume: 9, P: 1-17
Exosomes secreted from cardiomyocytes suppress the sensitivity of tumor ferroptosis in ischemic heart failure

Ye Yuan
Zhongting Mei
Baofeng Yang
ResearchOpen Access27 Mar 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-15
Hypoxia-induced long noncoding RNA NR2F1-AS1 maintains pancreatic cancer proliferation, migration, and invasion by activating the NR2F1/AKT/mTOR axis

Yanqing Liu
Shiyu Chen
Chengyi Sun
ResearchOpen Access14 Mar 2022
Cell Death & Disease

Volume: 13, P: 1-14
Strong Fe³⁺-O(H)-Pt Interfacial Interaction Induced Excellent Stability of Pt/NiFe-LDH/rGO Electrocatalysts

Yechuang Han
Pengfei Li
Changhao Liang
ResearchOpen Access22 Jan 2018
Scientific Reports

Volume: 8, P: 1-9
ARHGAP4 promotes leukemogenesis in acute myeloid leukemia by inhibiting DRAM1 signaling

Yan Qi
Mengjia Hu
Dongfeng Zeng
Research13 Jul 2023
Oncogene

Volume: 42, P: 2547-2557
Effective routing design for remote entanglement generation on quantum networks

Changhao Li
Tianyi Li
Paola Cappellaro
ResearchOpen Access27 Jan 2021
npj Quantum Information

Volume: 7, P: 1-12
Temporal relationship between hyperuricemia and obesity, and its association with future risk of type 2 diabetes

Tianshu Han
Xing Meng
Changhao Sun
Research01 May 2018
International Journal of Obesity

Volume: 42, P: 1336-1344
Heat acclimation in mice requires preoptic BDNF neurons and postsynaptic potentiation

Baoting Chen
Cuicui Gao
Wei L. Shen
CorrespondenceOpen Access26 Dec 2024
Cell Research

Volume: 35, P: 224-227
SUMOylation-triggered ALIX activation modulates extracellular vesicles circTLCD4-RWDD3 to promote lymphatic metastasis of non-small cell lung cancer

Xiayao Diao
Chao Guo
Shanqing Li
ResearchOpen Access04 Nov 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-17
Molecular-electromechanical system for unamplified detection of trace analytes in biofluids

We present the design, assembly and implementation of a molecular-electromechanical system composed of a tetrahedral DNA nanostructure immobilized on a graphene field-effect transistor for unamplified detection of trace amounts of analytes in biofluids.

Xuejun Wang
Changhao Dai
Dacheng Wei
Protocols19 May 2023
Nature Protocols

Volume: 18, P: 2313-2348
Understanding the Solvent Molecules Induced Spontaneous Growth of Uncapped Tellurium Nanoparticles

Jun Liu
Changhao Liang
Shouliang Wu
ResearchOpen Access07 Sept 2016
Scientific Reports

Volume: 6, P: 1-10
Serological and clinical associations of autoantibodies in Chinese patients with new-onset systemic lupus erythematosus

Muxue Gong
Li Dai
Changhao Xie
ResearchOpen Access21 Jun 2023
Scientific Reports

Volume: 13, P: 1-9
Development and validation of a discrimination model between primary PLA2R-negative membranous nephropathy and minimal change disease confirmed by renal biopsy

Feng Wu
Yiding Zhang
Zhanzheng Zhao
ResearchOpen Access10 Sept 2021
Scientific Reports

Volume: 11, P: 1-11
Efficient electrocatalytic nitrogen reduction to ammonia with aqueous silver nanodots

Nano-sized catalysts are useful for electrocatalytic nitrogen reduction, but loading the particles on electrode substrates can limit catalytic performance. Here, the authors report nitrogen to ammonia electroreduction mediated by silver nanodots dispersed in an aqueous solution.

Wenyi Li
Ke Li
Huijun Zhao
ResearchOpen Access29 Jan 2021
Communications Chemistry

Volume: 4, P: 1-11
In vivo biodistribution and toxicity of intravesical administration of quantum dots for optical molecular imaging of bladder cancer

Ying Pan
Timothy Chang
Joseph C. Liao
ResearchOpen Access24 Aug 2017
Scientific Reports

Volume: 7, P: 1-9
Dietary Protein Intake and Type 2 Diabetes Among Women and Men in Northeast China

Jie Li
Changhao Sun
Ying Li
ResearchOpen Access29 Nov 2016
Scientific Reports

Volume: 6, P: 1-9
AP4 modulated by the PI3K/AKT pathway promotes prostate cancer proliferation and metastasis of prostate cancer via upregulating L-plastin

Changhao Chen
Qingqing Cai
Tianxin Lin
ResearchOpen Access05 Oct 2017
Cell Death & Disease

Volume: 8, P: e3060
Interoceptive regulation of skeletal tissue homeostasis and repair

Yao Xiao
Changhao Han
Shen Liu
ReviewsOpen Access05 Sept 2023
Bone Research

Volume: 11, P: 1-16

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