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Nature Biotechnology (6)
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Showing 1–10 of 10 results

Advanced filters: Author: Changming Luan Clear advanced filters

Efficient mitochondrial A-to-G base editors for the generation of mitochondrial disease models

Efficient adenine base editors for mitochondrial DNA are achieved with evolved TadA deaminases.

Liang Chen
Mengjia Hong
Dali Li
Research03 Jun 2025
Nature Biotechnology

P: 1-12
A mitochondrial disease model is generated and corrected using engineered base editors in rat zygotes

A mitochondrial disease is modeled using engineered base editors in rats.

Liang Chen
Changming Luan
Dali Li
Research03 Jun 2025
Nature Biotechnology

P: 1-5
Author Correction: Adenine transversion editors enable precise, efficient A•T-to-C•G base editing in mammalian cells and embryos

Liang Chen
Mengjia Hong
Dali Li
Amendments and Corrections24 Apr 2024
Nature Biotechnology

Volume: 42, P: 987
Author Correction: Engineering a precise adenine base editor with minimal bystander editing

Liang Chen
Shun Zhang
Dali Li
Amendments and Corrections22 Apr 2024
Nature Chemical Biology

Volume: 20, P: 1094
Author Correction: Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing

Liang Chen
Biyun Zhu
Dali Li
Amendments and Corrections24 Apr 2024
Nature Biotechnology

Volume: 42, P: 987
Adenine transversion editors enable precise, efficient A•T-to-C•G base editing in mammalian cells and embryos

A base editor for precise adenine transversions is demonstrated in mouse embryos.

Liang Chen
Mengjia Hong
Dali Li
Research15 Jun 2023
Nature Biotechnology

Volume: 42, P: 638-650
Direct vegetation response to recent CO₂ rise shows limited effect on global streamflow

The impact of elevated atmospheric CO₂ on river flow remains uncertain. This study uses statistical models, constrained by global streamflow data, to demonstrate that CO₂ has a limited direct effect on streamflow at both catchment and global scales.

Haoshan Wei
Yongqiang Zhang
Changming Liu
ResearchOpen Access31 Oct 2024
Nature Communications

Volume: 15, P: 1-9
Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing

Improved cytosine base editors are created by repurposing an adenine deaminase.

Liang Chen
Biyun Zhu
Dali Li
Research10 Nov 2022
Nature Biotechnology

Volume: 41, P: 663-672
Engineering a precise adenine base editor with minimal bystander editing

A precise adenine base editor variant, ABE9, was developed to generate single adenine transition at pathogenic homopolymeric adenine sites with minimal DNA/RNA off-target effects, suggesting promising potential for gene therapeutics.

Liang Chen
Shun Zhang
Dali Li
Research13 Oct 2022
Nature Chemical Biology

Volume: 19, P: 101-110
Multi-decadal trends in global terrestrial evapotranspiration and its components

Yongqiang Zhang
Jorge L. Peña-Arancibia
Ming Pan
ResearchOpen Access11 Jan 2016
Scientific Reports

Volume: 6, P: 1-12