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Antiferromagnets are promising for nano-oscillator in terahertz frequency. However, realizing antiferromagnetic moment oscillation via spin-orbit torque remains elusive. Here, the authors demonstrate oscillations in Mn₂Au films.

Enhancing the arsenal of E3 ligases is important for PROTACs development. Here, the authors identify a non-inhibitory aptameric ligand to CRL2^ZYG11B E3 ligase, and develop a general, modular, and straightforward aptamer-based PROTAC platform, termed ZATAC, providing insights for untapped E3 ligases.

Qin et al. realized a plasmonic exceptional point distribution that covers full Poincaré sphere based on extrinsic chirality and basis transformation, extending the application of singularity induced topological phase to arbitrary polarization states.

Here the authors immobilize quaternary ammonium cations on the surface of Cu catalyst to suppress the carbonate precipitation, achieving a Faradaic efficiency of 50% for ethylene product at 200 mA/cm² from CO₂ electroreduction.

A light-inducible RNA base editor fine-tunes gene expression for therapeutics.

An annually resolved 3476-year tree-ring record from the Tibetan Plateau reveals severe 20^th century droughts and highlights the interplay between the Asian Monsoon and Westerlies. Droughts are often linked to the collapse of dynasties.

Genome-wide association studies (GWAS) have improved our understanding of the genetic basis of lung adenocarcinoma but known susceptibility variants explain only a small fraction of the familial risk. Here, the authors perform a two-stage GWAS and report 12 novel genetic loci associated with lung adenocarcinoma in East Asians.

As presented at the 2025 AACR Annual Meeting, in an ongoing first-in-human phase 1 trial of a next-generation KRAS-G12C inhibitor in patients with solid tumors, encouraging safety and response results were observed, including in patients with non-small-cell lung cancer.

The instability of quantum dot inks hinders the scaling up of colloidal quantum dot electronics. Now, Shi and team stabilize the inks with an iodine-rich environment in a weakly coordinating solvent, achieving 13.4% in small-area solar cells and over 10% in modules.

Drug resistance is inevitable and pervasive. Here, the authors identify the V517F mutation as a significant contributor to USP7-mediated inhibitor resistance. This discovery offers valuable insights for the development of next-generation USP7 inhibitors.

The advent of isolated attosecond XUV pulse sources marks a new era in attosecond science, pivotal for the investigation of core electron dynamics. Here the authors discover that the coherent Raman coupling between the cation states leads to extra timedelay between different transition channels by applying the attosecond transient absorption spectroscopy on the investigation of complex dynamics of strong field ionization of Krypton.

The synthesis of covalent organic frameworks with a multiple-dynamic-bonds strategy realizes selective extraction of uranyl tricarbonate anions from ultra-low concentrations and multiple interfering ions.

Many sporadic cases of hypertrophic cardiomyopathy have unknown genetic basis. Here, the authors identify a mutation in the gene NAP1L1 to be associated with cases of hypertrophic cardiomyopathy, linking it to cGAS-STING-IFN signaling.

xTrimo protein general language model (xTrimoPGLM) is a unified pretraining framework and foundation model designed for various protein-related tasks, including protein understanding and generation or design.

Previous multi-wavelength metasurfaces are restricted to a few wavelengths or lack wavefront control ability. Here, the authors introduce a microcavity-assisted metasurface that achieves multi-resonant wavefront engineering at 15 high-Q peak wavelengths from 480 nm to 1000 nm.

Molecular interactions are of great importance in materials science. Here, the authors use the confinement effect and low-dose imaging to reveal the confined molecules and evaluate the strength of host-guest interactions in different material systems.

Chen et al. report a large-area white LED with sunlight-like emission by regulating the heterophase γ/σ-CsPb(I/Cl)₃ at nanoscale, in which a fraction of carriers recombines in γ-CsPbI₃ for deep-red emission, while other carriers diffuse to the heterophase interface for broadband emission.

Biocompatible afterglow materials have potential in imaging applications, but are challenging to prepare. Here the authors report the development of carbon nanodots with near-infrared afterglow, and demonstrate their use in imaging for tumour resection.

The authors demonstrate an efficient way to generate high-purity vortex beams by applying optical neural networks to cascaded phase-only metasurfaces. Specifically, they present record-high-quality Laguerre-Gaussian (LG_p,l) optical modes with polynomial orders p = 10 and l = 200 with purity in p, l and relative conversion efficiency of 96%, 85%, and 70%, respectively.

Hydrogen production coupled with electrochemical oxidation of organic nucleophiles is often limited by catalyst’s reconstruction at the anode. Here, the authors developed the stable Ni(II) active sites in Prussian Blue analogue for fast, selective ethylene glycol electrooxidation and constructed an effective coupled electrochemical hydrogen production flow cell.

A surface charge visualization and standardized quantification method and surface charge tuning is achieved for triboelectric materials, delivering essential tools for contact electrification and high-performance triboelectric nanogenerators.

All-electrical excitation of the hyperbolic phonon polaritons in hexagonal boron nitride by drifting charge carriers in nearby graphene results in electroluminescence at mid-infrared frequencies.

Néel spin-orbit torques arise due to charge currents in some antiferromagnets, and have sparked interest as a possible pathway for achieving electrical control of antiferromagnetic order. While the driving of antiferromagnetic order by Néel spin-orbit torques is now experimentally well established, the inverse process, where magnetic excitations in an antiferromagnetic drive a charge current is not reported. Here Huang, Liao, Qiu, and coauthors observe this inverse process in an Mn2Au thin film.

Skyrmions are a type of topological spin texture that have generate considerable interest for use in information storage and processing, and unconventional computing. Despite this interest, controlled generation, and motion without a Skyrmion hall effect remain an issue. Here, Chen et al combine a Skyrmion hosting magnetic multilayer with a surface acoustic wave (SAW) delay line, and show how SAWs can create, order, and allow for Skyrmion motion, without the Skyrmion Hall effect.

The conversational diagnostic artificial intelligence system AMIE (Articulate Medical Intelligence Explorer) has potential as a real-world tool for clinical history-taking and diagnostic dialogue, based on its performance in simulated consultations.

Common aromatic rings, such as anilines, arylboronic acids and aryl halides, can be opened up and converted to alkenyl nitriles through carbon–carbon bond cleavage using a copper catalyst.

Achieving sustainability in wireless communications is crucial yet poses significant challenges. To address this, the authors propose and demonstrate a solar-powered programmable metasurface enabling hybrid light-to-microwave wireless communications.

The neurovirulence determinants of Zika virus remain not fully established. Song et al identified a single K101R substitution in the capsid protein that contributes to the lineage-specific virulence phenotypes.

Fu et al. describe a pathogen effector, HaRxL10 that suppresses plant immunity and interferes with plant development by hijacking the clock component CHE to perturb its function in transcriptional regulation.

The altermagnetic order in CrSb films can be manipulated via crystal symmetry; the reconstructed altermagnetic order generates a room-temperature spontaneous anomalous Hall effect and designable switching modes as field-assisted and field-free modes.

Experimental investigation on skyrmion bags focuses on single-phase materials. Here, the authors demonstrate room-temperature creation, conversion and zero-field stability of individual skyrmion bags in magnetic multilayered disks.

Here, the authors introduce Photoacoustic Tomography with Temporal Encoding Reconstruction (PATTERN) - a high-speed, non-destructive photoacoustic brain imaging technique that constructs 3D fluorescent maps of the brain and improves upon some of the limitations associated with traditional whole-brain optical imaging techniques.

Highly specific glycan labels remain scarce, limiting their use in many applications. Here, authors report recombinant glycan affinity binders based on sialidase mutants, which are enzymatically inactive but preserve specificity for sialoglycans.

The availability of relevant animal models that can recapitulate high-risk hepatoblastoma will help to better understand its pathogenesis. Here the authors report and characterize a hepatocyte-specific, MYC-driven hepatoblastoma mouse model and show it recapitulates the human hepatoblastoma pathophysiology.

Due to their layered structure, and resulting weak interlayer exchange coupling, van der Waals materials can exhibit distinct behaviour depending on whether the spins are aligned in the plane, or perpendicular. Here, via magnetoresistance measurements, Zhu et al provide direct evidence of a magneto-band-structure effect due to the alignment of the spin in the van der Waals magnet, Cr₂Ge₂Te₆.

Maximizing metal-substrate interactions through self-reconstruction is a key strategy for efficient oxygen evolution catalysts. Here, the authors report high-density iridium atoms embedded in ultrathin oxyhydroxide nanosheets, showing high performance in the oxygen evolution reaction.

Hyperbolic shear polaritons (HShPs) are strongly confined light-matter excitations that have been previously observed in low-symmetry 3D materials with limited tunability. Here, the authors report the observation and manipulation of HShPs in twisted bilayers α-MoO₃ by tuning the sample structure or using a graphene electrostatic gate.

Combining metal catalysis and organocatalysis can be difficult, especially when dealing with strongly coordinating organic compounds such as N-heterocyclic carbenes. Here, the authors combine copper and N-heterocyclic carbene catalysis for the generation of ketimines and their use in stereoselective reactions.

Quantum speed limits are fundamental constraints on the speed of quantum state evolution. Here, the authors observe the known maximal quantum speed limits for few and many-body states on a superconducting quantum processor and identify the minimal quantum speed limits, which are less common than maximal ones.

A wax-aided immersion methodology is developed to yield graphene rolls with tunable chiral angles; these graphene rolls exhibit promising chiral electronic properties beyond those of other carbon allotropes.

A real–momentum topological photonic crystal that harnesses real-space disorder is used to generate a Pancharatnam–Berry phase while preserving momentum-space topology.