Nature Search

A deep learning system for detecting silent brain infarction and predicting stroke risk

DeepRETStroke is a deep learning system using retinal photographs to detect silent brain infarction and predict future stroke events.

Nan Jiang
Hongwei Ji
Tien Yin Wong
ResearchOpen Access06 Jun 2025
Nature Biomedical Engineering

P: 1-13
A standalone bismuth vanadate-silicon artificial leaf achieving 8.4% efficiency for hydrogen production

A BiVO₄ photoanode with oxygen vacancy gradients was developed and coupled with a silicon photovoltaic cell to form a standalone artificial leaf. It achieves a solar-to-hydrogen efficiency of 8.4% for solar water splitting with >500 h of stability.

Boyan Liu
Xin Wang
Songcan Wang
ResearchOpen Access21 Mar 2025
Nature Communications

Volume: 16, P: 1-13
Integrated image-based deep learning and language models for primary diabetes care

Tailored to provide diabetes management recommendations from large training and validation datasets, an artificial intelligence system integrating language and computer vision capabilities is shown to improve self-management of patients in a prospective implementation study.

Jiajia Li
Zhouyu Guan
Tien Yin Wong
ResearchOpen Access19 Jul 2024
Nature Medicine

Volume: 30, P: 2886-2896
A deep learning system for predicting time to progression of diabetic retinopathy

A deep learning algorithm shows promising performance in predicting progression to diabetic retinopathy in patients, up to 5 years in advance, potentially providing support for medical treatment decisions and indications for personalized screening frequency in a real-world cohort.

Ling Dai
Bin Sheng
Weiping Jia
ResearchOpen Access04 Jan 2024
Nature Medicine

Volume: 30, P: 584-594
Hydrocarbon generation potential and geochemical characteristics comparison of source rocks in the Southwestern Qaidam basin, China

Yang Zhao
Chenxin Huang
Qingyou Yue
ResearchOpen Access10 Mar 2025
Scientific Reports

Volume: 15, P: 1-16
Highly stretchable polymer semiconductor thin films with multi-modal energy dissipation and high relative stretchability

Stretchable polymer semiconductors with high mechanical and electrical properties are challenging to develop. Wu et al. show that reversible molecular ordering under strain important for performance optimization and relative stretchability can be used to compare the relative strain tolerance of materials.

Hung-Chin Wu
Shayla Nikzad
Zhenan Bao
ResearchOpen Access16 Dec 2023
Nature Communications

Volume: 14, P: 1-10
Genetically encoded photocatalytic protein labeling enables spatially-resolved profiling of intracellular proteome

Mapping the subcellular organization of proteins is crucial for understanding their biological functions. Here, the authors develop a genetically encoded photocatalytic labeling method for profiling the subcellular proteome in multiple organelles.

Fu Zheng
Chenxin Yu
Peng Zou
ResearchOpen Access23 May 2023
Nature Communications

Volume: 14, P: 1-14
Single-cell multi-omics in the medicinal plant Catharanthus roseus

The medicinal plant Catharanthus roseus is a source of leading anticancer drugs. The monoterpene indole alkaloid (MIA) biosynthetic pathway in C. roseus has now been analyzed using a complementary, multi-omics, single-cell approach. This identified clusters of genes involved in MIA biosynthesis and cell-type-specific partitioning in the MIA biosynthetic pathway.

Chenxin Li
Joshua C. Wood
C. Robin Buell
ResearchOpen Access15 May 2023
Nature Chemical Biology

Volume: 19, P: 1031-1041
Neurofilament light chain as a mediator between LRRK2 mutation and dementia in Parkinson’s disease

Dehao Yang
Haobo Xie
Guangyong Chen
ResearchOpen Access12 Sept 2023
npj Parkinson's Disease

Volume: 9, P: 1-6
Similarity based city data transfer framework in urban digitization

Haoxiang Wang
Xiaoping Che
Pengfei Li
ResearchOpen Access28 Mar 2025
Scientific Reports

Volume: 15, P: 1-16
Low-voltage high-performance flexible digital and analog circuits based on ultrahigh-purity semiconducting carbon nanotubes

Carbon nanotube thin-film transistor is promising for solution-processed, large-scale flexible electronics, but the device yields remain poor to date. Lei et al. show low-voltage flexible digital and analog circuits based on high-purity and high-yield separation of semiconducting carbon nanotubes.

Ting Lei
Lei-Lai Shao
Zhenan Bao
ResearchOpen Access14 May 2019
Nature Communications

Volume: 10, P: 1-10
Method for detecting cracks in retaining walls based on improved YOLOv5s

Yanhai Wang
Chenxin Guo
Huafeng Deng
ResearchOpen Access20 Feb 2025
Scientific Reports

Volume: 15, P: 1-11
A noncanonical function of EIF4E limits ALDH1B1 activity and increases susceptibility to ferroptosis

Ferroptosis is lipid peroxidation-dependent cell death that has potential to be harnessed as a cancer therapeutic. Here, the authors show that the translation initiation factor eIF4E can repress ALDH1B1 independent of translation, increasing lipid peroxidation levels to promote ferroptosis.

Xin Chen
Jun Huang
Rui Kang
ResearchOpen Access23 Oct 2022
Nature Communications

Volume: 13, P: 1-16
A non-invasive method to determine the pluripotent status of stem cells by culture medium microRNA expression detection

Ying Zhang
Gui-Hai Feng
Qi Zhou
ResearchOpen Access01 Mar 2016
Scientific Reports

Volume: 6, P: 1-8
Author Correction: LRIG1 is a pleiotropic androgen receptor-regulated feedback tumor suppressor in prostate cancer

Qiuhui Li
Bigang Liu
Dean G. Tang
Amendments and CorrectionsOpen Access04 Jun 2020
Nature Communications

Volume: 11, P: 1
Imaging-based body fat distribution and diabetic retinopathy in general US population with diabetes: an NHANES analysis (2003–2006 and 2011–2018)

Chenxin Li
Yili Zhang
Zhi Zheng
ResearchOpen Access14 Jul 2024
Nutrition & Diabetes

Volume: 14, P: 1-9
LRIG1 is a pleiotropic androgen receptor-regulated feedback tumor suppressor in prostate cancer

LRIG1 is a tumour suppressor in several cancers. Here, the authors show that androgen receptor directly transactivates LRIG1 which then antagonises ERBB signalling and c-Myc expression to inhibit prostate tumorigenesis.

Qiuhui Li
Bigang Liu
Dean G. Tang
ResearchOpen Access02 Dec 2019
Nature Communications

Volume: 10, P: 1-19
High-efficiency targeted transgene integration via primed micro-homologues

Chenxin Wang
Sen Fang
Wei Li
ResearchOpen Access04 Jul 2023
Cell Discovery

Volume: 9, P: 1-14
RANKL/RANK signaling recruits Tregs via the CCL20–CCR6 pathway and promotes stemness and metastasis in colorectal cancer

Jing Ouyang
Shuang Hu
Chengming Zhu
ResearchOpen Access20 Jun 2024
Cell Death & Disease

Volume: 15, P: 1-12
The efficacy and safety of CAR-T cell therapy in patients with refractory ALL and concomitant HBV infection

Peilong Lai
Xiaomei Chen
Jianyu Weng
Research06 Jul 2020
Leukemia

Volume: 34, P: 2790-2793
Risk factors for secondary thyroid cancer in patients with breast cancer: a propensity‑matched SEER analysis

Yizhuo Diao
Ruiqi Wang
Xiaofeng Li
ResearchOpen Access03 Jun 2024
Scientific Reports

Volume: 14, P: 1-11
Risk factor analysis and nomogram establishment and verification of brain astrocytoma patients based on SEER database

Ruiqi Wang
Jiaxue Cui
Xiaofeng Li
ResearchOpen Access12 May 2023
Scientific Reports

Volume: 13, P: 1-19
Volume development changes in the occipital lobe gyrus assessed by MRI in fetuses with isolated ventriculomegaly correlate with neurological development in infancy and early childhood

Xin Zhang
Zhaoji Chen
Hongsheng Liu
Research27 May 2024
Journal of Perinatology

Volume: 44, P: 1178-1185
Portable visual and electrochemical detection of hydrogen peroxide release from living cells based on dual-functional Pt-Ni hydrogels

Guanglei Li
Yao Chen
Dan Wen
ResearchOpen Access29 Nov 2023
Microsystems & Nanoengineering

Volume: 9, P: 1-10
Synchronous profiling of mRNA N6-methyladenosine modifications and mRNA expression in high-grade serous ovarian cancer: a pilot study

Li Yang
Jingfang Liu
Aijun Yu
ResearchOpen Access07 May 2024
Scientific Reports

Volume: 14, P: 1-17
Combination therapy with HSP90 inhibitors and piperlongumine promotes ROS-mediated ER stress in colon cancer cells

Chenyu Qiu
Xin Shen
Jundixia Chen
ResearchOpen Access13 Oct 2023
Cell Death Discovery

Volume: 9, P: 1-13
Diversity of rice rhizosphere microorganisms under different fertilization modes of slow-release fertilizer

Yulin Chen
Panfeng Tu
Lansheng Deng
ResearchOpen Access17 Feb 2022
Scientific Reports

Volume: 12, P: 1-13
Effects of urbanization on productivity of terrestrial ecological systems based on linear fitting: a case study in Jiangsu, eastern China

Jianguo Li
Chenxin Zou
Lili Liu
ResearchOpen Access20 Nov 2019
Scientific Reports

Volume: 9, P: 1-10
Deep representation features from DreamDIA^XMBD improve the analysis of data-independent acquisition proteomics

Gao et al. report DreamDIA^XMBD, a deep learning-based tool, that can extract and score chromatogram features, improving the performance of peptide-centric DIA data analysis. In contrast to the existing tools, DreamDIA^XMBD demonstrates higher numbers of precursor identifications and accurate quantification in public test data sets.

Mingxuan Gao
Wenxian Yang
Jiahuai Han
ResearchOpen Access14 Oct 2021
Communications Biology

Volume: 4, P: 1-10
Maternal linoleic acid-rich diet ameliorates bilirubin neurotoxicity in offspring mice

Ding Yan
XinTian Wu
Jinbao Liu
ResearchOpen Access19 Jul 2024
Cell Death Discovery

Volume: 10, P: 1-12
Enhanced Notch3 signaling contributes to pulmonary emphysema in a Murine Model of Marfan syndrome

Kathryn Jespersen
Zhibo Liu
Wanfen Xiong
ResearchOpen Access02 Jul 2020
Scientific Reports

Volume: 10, P: 1-11
Pharmacological characterization of a novel metal-based proteasome inhibitor Na-AuPT for cancer treatment

Da-cai Xu
Li Yang
Jin-bao Liu
Research10 Dec 2021
Acta Pharmacologica Sinica

Volume: 43, P: 2128-2138
Targeting proteasomal deubiquitinases USP14 and UCHL5 with b-AP15 reduces 5-fluorouracil resistance in colorectal cancer cells

Wa Ding
Jin-xiang Wang
Xian-ping Shi
Research01 Aug 2023
Acta Pharmacologica Sinica

Volume: 44, P: 2537-2548
The deubiquitinating enzyme STAMBP is a newly discovered driver of triple-negative breast cancer progression that maintains RAI14 protein stability

Qianqian Yang
Ding Yan
Jinbao Liu
ResearchOpen Access25 Nov 2022
Experimental & Molecular Medicine

Volume: 54, P: 2047-2059
Regulation of Bax-dependent apoptosis by mitochondrial deubiquitinase USP30

Ding Yan
Xiaofen Li
Xin Chen
ResearchOpen Access11 Aug 2021
Cell Death Discovery

Volume: 7, P: 1-11
Oxidative cell death in cancer: mechanisms and therapeutic opportunities

Xiaoqin An
Wenfeng Yu
Xin Chen
ReviewsOpen Access01 Aug 2024
Cell Death & Disease

Volume: 15, P: 1-20

Search

A deep learning system for detecting silent brain infarction and predicting stroke risk

A standalone bismuth vanadate-silicon artificial leaf achieving 8.4% efficiency for hydrogen production

Integrated image-based deep learning and language models for primary diabetes care

A deep learning system for predicting time to progression of diabetic retinopathy

Hydrocarbon generation potential and geochemical characteristics comparison of source rocks in the Southwestern Qaidam basin, China

Highly stretchable polymer semiconductor thin films with multi-modal energy dissipation and high relative stretchability

Genetically encoded photocatalytic protein labeling enables spatially-resolved profiling of intracellular proteome

Single-cell multi-omics in the medicinal plant Catharanthus roseus

Neurofilament light chain as a mediator between LRRK2 mutation and dementia in Parkinson’s disease

Similarity based city data transfer framework in urban digitization

Low-voltage high-performance flexible digital and analog circuits based on ultrahigh-purity semiconducting carbon nanotubes

Method for detecting cracks in retaining walls based on improved YOLOv5s

A noncanonical function of EIF4E limits ALDH1B1 activity and increases susceptibility to ferroptosis

A non-invasive method to determine the pluripotent status of stem cells by culture medium microRNA expression detection

Author Correction: LRIG1 is a pleiotropic androgen receptor-regulated feedback tumor suppressor in prostate cancer

Imaging-based body fat distribution and diabetic retinopathy in general US population with diabetes: an NHANES analysis (2003–2006 and 2011–2018)

LRIG1 is a pleiotropic androgen receptor-regulated feedback tumor suppressor in prostate cancer

High-efficiency targeted transgene integration via primed micro-homologues

RANKL/RANK signaling recruits Tregs via the CCL20–CCR6 pathway and promotes stemness and metastasis in colorectal cancer

The efficacy and safety of CAR-T cell therapy in patients with refractory ALL and concomitant HBV infection

Risk factors for secondary thyroid cancer in patients with breast cancer: a propensity‑matched SEER analysis

Risk factor analysis and nomogram establishment and verification of brain astrocytoma patients based on SEER database

Volume development changes in the occipital lobe gyrus assessed by MRI in fetuses with isolated ventriculomegaly correlate with neurological development in infancy and early childhood

Portable visual and electrochemical detection of hydrogen peroxide release from living cells based on dual-functional Pt-Ni hydrogels

Synchronous profiling of mRNA N6-methyladenosine modifications and mRNA expression in high-grade serous ovarian cancer: a pilot study

Combination therapy with HSP90 inhibitors and piperlongumine promotes ROS-mediated ER stress in colon cancer cells

Diversity of rice rhizosphere microorganisms under different fertilization modes of slow-release fertilizer

Effects of urbanization on productivity of terrestrial ecological systems based on linear fitting: a case study in Jiangsu, eastern China

Deep representation features from DreamDIA^XMBD improve the analysis of data-independent acquisition proteomics

Maternal linoleic acid-rich diet ameliorates bilirubin neurotoxicity in offspring mice

Enhanced Notch3 signaling contributes to pulmonary emphysema in a Murine Model of Marfan syndrome

Pharmacological characterization of a novel metal-based proteasome inhibitor Na-AuPT for cancer treatment

Targeting proteasomal deubiquitinases USP14 and UCHL5 with b-AP15 reduces 5-fluorouracil resistance in colorectal cancer cells

The deubiquitinating enzyme STAMBP is a newly discovered driver of triple-negative breast cancer progression that maintains RAI14 protein stability

Regulation of Bax-dependent apoptosis by mitochondrial deubiquitinase USP30

Oxidative cell death in cancer: mechanisms and therapeutic opportunities

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