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Showing 1–2 of 2 results
Advanced filters: Author: Christopher Eickhorst Clear advanced filters

  • Denervation leads to muscle atrophy and neuromuscular endplate remodeling. Here, the authors show that a balanced activation of mTORC1 contributes to the dynamic regulation of autophagic flux in denervated muscle and that activation of PKB/Akt promotes the nuclear import of HDAC4, which is essential for endplate maintenance upon nerve injury

    • Perrine Castets
    • Nathalie Rion
    • Markus A. Rüegg
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-16