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Showing 1–9 of 9 results
Advanced filters: Author: Christopher Penfold Clear advanced filters

  • 3D transcriptomes reveal the molecular code of lineage specification in the primate embryo and provide an in vivo reference to decipher human development.

    • Sophie Bergmann
    • Christopher A. Penfold
    • Thorsten E. Boroviak
    Research
    Nature
    Volume: 609, P: 136-143

  • Nonadiabatic excited state processes involve mixing of electronic and nuclear wavefunctions, which are difficult to disentangle. Here the authors explore by time-resolved X-ray absorption near edge structure the wavepacket dynamics of a copper(I)-phenanthroline complex, resolving different vibrational modes.

    • Tetsuo Katayama
    • Thomas Northey
    • Thomas J. Penfold
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-8

  • Mammalian embryogenesis relies on glycolysis and oxidative phosphorylation, but understanding of the dynamics of metabolic regulation in the postimplantation embryo in vivo remains elusive. Here the authors compile single-cell embryo profiling data in six mammalian species and reveal a conserved metabolic programme despite different implantation modes.

    • Anna Malkowska
    • Christopher Penfold
    • Thorsten E. Boroviak
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-12

  • The change from low-spin hexacoordinated to high-spin pentacoordinated domed form in heam upon ligand detachment and the reverse process underlie the respiratory function. The authors, using femtosecond time-resolved X-ray emission spectroscopy, capture the transient states connecting the two forms in myoglobin-NO upon NO photoinduced detachment.

    • Dominik Kinschel
    • Camila Bacellar
    • Majed Chergui
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-8

  • Metal-oxide nanostructures are used in a range of light-driven applications, yet the fundamentals behind their properties are poorly understood. Here the authors probe photoexcited zinc oxide nanoparticles using time-resolved X-ray spectroscopy, identifying photocatalytically-active hole traps as oxygen vacancies in the lattice.

    • Thomas J. Penfold
    • Jakub Szlachetko
    • Christopher J. Milne
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-9

  • Bergmann et al. discuss the construction of synthetic uteri to model the earliest stages of human embryogenesis and associated pathologies. They highlight the constituent components from which a synthetic uterus may be engineered, propose a modular approach to assembling synthetic uteri and discuss how these technologies can shed light on implantation failure and uterine pathologies.

    • Sophie Bergmann
    • Magdalena Schindler
    • Thorsten E. Boroviak
    ReviewsOpen Access
    Communications Biology
    Volume: 4, P: 1-12