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Advanced filters: Author: Chun-Gu Hong Clear advanced filters

Reassessing endothelial-to-mesenchymal transition in mouse bone marrow: insights from lineage tracing models

Endothelial cells (ECs) and bone marrow stromal cells (BMSCs) support hematopoiesis and hematopoietic regeneration. Whether ECs are a source of BMSCs remains unclear. Here, using lineage tracing models the authors show that ECs are not a source of BMSCs during homeostasis and regeneration.

Jia Cao
Ling Jin
Hui Xie
ResearchOpen Access20 Dec 2023
Nature Communications

Volume: 14, P: 1-15
Fasting activates optineurin-mediated mitophagy in chondrocytes to protect against osteoarthritis

OPTN-mediated mitophagy plays a key role in OA progression. OPTN deficiency leads to mitochondrial damage and chondrocyte apoptosis, while fasting alleviates OA by activating OPTN-mediated mitophagy, offering a potential therapeutic target for OA

Min-Na Zhang
Ran Duan
Zheng-Zhao Liu
ResearchOpen Access16 Jan 2025
Communications Biology

Volume: 8, P: 1-12
Transplantation of olfactory mucosa mesenchymal stromal cells repairs spinal cord injury by inducing microglial polarization

Xin Wang
Chun-Gu Hong
Zheng-Zhao Liu
Research07 Jun 2024
Spinal Cord

Volume: 62, P: 429-439

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