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Scientific Reports (21)
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Showing 1–50 of 69 results

Advanced filters: Author: Chunyan Song Clear advanced filters

Analysis of the Rehmannia chingii geneome identifies RcCYP72H7 as an epoxidase in iridoid glycoside biosynthesis

Rehmannia chingii is a traditional Chinese medicinal plant that can produce iridoid glycoside. Here, the authors report its genome assembly and the elucidation of the iridoid biosynthetic pathway.

Fengqing Wang
Zhennan Jiang
Yuan Yuan
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-17
A facultative plasminogen-independent thrombolytic enzyme from Sipunculus nudus

Many thrombolytic agents depend on plasminogen, leading to D-dimer accumulation. Here, Tang et al. report a plasminogen-independent thrombolytic enzyme that degrades blood clots and D-dimer without plasminogen.

Mingqing Tang
Guoxing Ma
Ruian Xu
ResearchOpen Access24 Apr 2025
Nature Communications

Volume: 16, P: 1-19
LOXL2 reduces susceptibility to PARP inhibitors by promoting super-enhancer-regulated DNA damage repair in high-grade serous ovarian cancer

Chunyan Song
Yaying Lin
Dan Liu
Research31 May 2025
Oncogene

P: 1-12
Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing

The molecular mechanism underlying how lithocholic acid recapitulates the lifespan and healthspan benefits of calorie restriction is revealed to involve TULP3, sirtuins, v-ATPase and AMPK.

Qi Qu
Yan Chen
Sheng-Cai Lin
ResearchOpen Access18 Dec 2024
Nature

P: 1-9
Association of KIR Genotypes and Haplotypes with Susceptibility to Chronic Hepatitis B Virus Infection in Chinese Han Population

Zhiming Lu
Bingchang Zhang
Yueran Zhao
Research01 Dec 2008
Cellular & Molecular Immunology

Volume: 5, P: 457-463
Cryptanalysis of efficient controlled semi-quantum secret sharing protocol with entangled state

Shuang Li
Xiao-Qiu Cai
Tian-Yin Wang
ResearchOpen Access29 Apr 2025
Scientific Reports

Volume: 15, P: 1-5
TFIP11 promotes replication fork reversal to preserve genome stability

The RAD51 recombinase plays a pivotal role in replication fork reversal during replication stress. Here, the authors show that the GCFC ___domain-containing protein TFIP11 interacts with BLM helicase and is important for fork reversal during replication stress to preserve genome stability.

Junliang Chen
Mingjie Wu
Ting Liu
ResearchOpen Access10 Feb 2024
Nature Communications

Volume: 15, P: 1-17
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK

A small-molecule aldolase inhibitor, aldolazin is reported and shown to selectively activate the lysosomal pool of AMPK, which has glucose-lowering effects in rodents.

Chen-Song Zhang
Mengqi Li
Sheng-Cai Lin
ResearchOpen Access10 Oct 2022
Nature Metabolism

Volume: 4, P: 1369-1401
Draft genome sequence of chickpea (Cicer arietinum) provides a resource for trait improvement

A draft sequence of the staple crop kabuli chickpea, together with resequencing and analysis of 90 additional lines from 10 countries, provides a resource for breeders.

Rajeev K Varshney
Chi Song
Douglas R Cook
ResearchOpen Access27 Jan 2013
Nature Biotechnology

Volume: 31, P: 240-246
Publisher Correction: Glycine max NNL1 restricts symbiotic compatibility with widely distributed bradyrhizobia via root hair infection

Bao Zhang
Mengdi Wang
Xuelu Wang
Amendments and Corrections08 Feb 2021
Nature Plants

Volume: 7, P: 239
Study on the mechanism of hsa_circ_0074763 regulating the miR-3667-3P/ACSL4 axis in liver fibrosis

Yanling Cheng
Tiantian Song
Fumin Feng
ResearchOpen Access27 Mar 2025
Scientific Reports

Volume: 15, P: 1-14
Visualizing designer quantum states in stable macrocycle quantum corrals

Creating atomically-precise quantum architectures with high digital fidelity and desired quantum states is an important goal for quantum technology applications. Here the authors devise an on-surface synthetic protocol to construct atomically-precise covalently linked organic quantum corrals with the formation of a series of new quantum resonance states.

Xinnan Peng
Harshitra Mahalingam
Jiong Lu
ResearchOpen Access08 Oct 2021
Nature Communications

Volume: 12, P: 1-9
Protective effect of total aralosides of Aralia elata (Miq) Seem (TASAES) against diabetic cardiomyopathy in rats during the early stage, and possible mechanisms

Shugang Xi
Guihua Zhou
Chunyan Zhao
ResearchOpen Access31 Aug 2009
Experimental & Molecular Medicine

Volume: 41, P: 538-547
Sb₂O₃/Ag/Sb₂O₃ Multilayer Transparent Conducting Films For Ultraviolet Organic Light-emitting Diode

Chunyan Song
Nan Zhang
Xingyuan Liu
ResearchOpen Access25 Jan 2017
Scientific Reports

Volume: 7, P: 1-7
Divergence and plasticity shape adaptive potential of the Pacific oyster

Adaptive differentiation is poorly understood in marine systems. Here, the authors combine genome sequencing with gene expression and physiology to show that genetic divergence and plasticity contribute to local adaptation of Pacific oyster populations.

Li Li
Ao Li
Guofan Zhang
Research24 Sept 2018
Nature Ecology & Evolution

Volume: 2, P: 1751-1760
Towards social sustainability in urban communities: exploring how community parks influence residents’ social interaction during the COVID-19 pandemic

Chunyan Yang
Song Shi
Duanfang Lu
ResearchOpen Access08 Nov 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-17
Optineurin modulates the maturation of dendritic cells to regulate autoimmunity through JAK2-STAT3 signaling

Optineurin (OPTN) has been implicated in various biological processes, but its function in dendritic cells (DC) maturation is still unclear. Here the authors show, by characterizing Optn-conditional knockout mice, that the loss of OPTN induces Jak2/Stat3 activation and IL-10 production to suppress DC maturation and function, thereby ameliorating autoimmune responses in mice.

Jiajia Wang
Jiaying Wang
Qinjie Weng
ResearchOpen Access27 Oct 2021
Nature Communications

Volume: 12, P: 1-15
Sparse deconvolution improves the resolution of live-cell super-resolution fluorescence microscopy

The resolution of fluorescence microscopy is increased by incorporating prior information into deconvolution algorithms.

Weisong Zhao
Shiqun Zhao
Liangyi Chen
Research15 Nov 2021
Nature Biotechnology

Volume: 40, P: 606-617
Structure-based investigation of fluorogenic Pepper aptamer

Structural analysis of the Pepper aptamer in complex with its cognate HBC or HBC-like color variants reveals that it binds fluorophore molecules via one non-G-quadruplex base quadruple and one noncanonical G·U base pair.

Kaiyi Huang
Xianjun Chen
Aiming Ren
Research01 Nov 2021
Nature Chemical Biology

Volume: 17, P: 1289-1295
Solar ultraviolet B radiation promotes α-MSH secretion to attenuate the function of ILC2s via the pituitary–lung axis

Allergic asthma is episodic and associated with seasonal changes which may have links with UV exposure levels. Here the authors propose a link between UVB exposure and ILC2 function through α-MSH released from the pituitary gland which accumulates in the serum and alters ILC2 function through the MC5R receptor.

Yuying Huang
Lin Zhu
Bing Sun
ResearchOpen Access12 Sept 2023
Nature Communications

Volume: 14, P: 1-16
Targeting HDACs for diffuse large B-cell lymphoma therapy

Chunyan Wu
Qiao Song
Shaoling Wu
ResearchOpen Access02 Jan 2024
Scientific Reports

Volume: 14, P: 1-11
Glycine max NNL1 restricts symbiotic compatibility with widely distributed bradyrhizobia via root hair infection

Soybean accessions display a variable number of nodules when colonized by rhizobia. The authors identify one locus controlling this trait, a typical TIR–NBS–LRR disease resistance gene called NNL1, and the corresponding bacterial effector called NopP.

Bao Zhang
Mengdi Wang
Xuelu Wang
Research15 Jan 2021
Nature Plants

Volume: 7, P: 73-86
The analysis of sanshan island based on constrained magnetization vector inversion

Hongbo Liu
Xiuzhang Li
Chunyan He
ResearchOpen Access07 Mar 2025
Scientific Reports

Volume: 15, P: 1-18
Genome structure and evolution of Antirrhinum majus L

This study reports a near-complete genome of Antirrhinum majus L., provides insights into gene and genome duplication events, and reveals the genetic basis underlying complex traits of snapdragon, such as flower asymmetry and self-incompatibility.

Miaomiao Li
Dongfen Zhang
Yongbiao Xue
ResearchOpen Access28 Jan 2019
Nature Plants

Volume: 5, P: 174-183
Numerical simulation analysis of carbon defects in the buffer on vertical leakage and breakdown of GaN on silicon epitaxial layers

Weicheng Cao
Chunyan Song
Hongyu Ji
ResearchOpen Access08 Sept 2023
Scientific Reports

Volume: 13, P: 1-7
Low-dose metformin targets the lysosomal AMPK pathway through PEN2

The molecular target of the antidiabetic medicine metformin is identified as PEN2, a subunit of γ-secretases, and the PEN2–ATP6AP1 axis offers potential targets for screening for metformin substitutes.

Teng Ma
Xiao Tian
Sheng-Cai Lin
ResearchOpen Access23 Feb 2022
Nature

Volume: 603, P: 159-165
Prognostic and predictive value of the newly proposed grading system of invasive pulmonary adenocarcinoma in Chinese patients: a retrospective multicohort study

Likun Hou
Tingting Wang
Xiaojie Pan
Research10 Jan 2022
Modern Pathology

Volume: 35, P: 749-756
Neoadjuvant chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in nasopharyngeal carcinoma patients with cervical nodal necrosis

Mei Lan
Chunyan Chen
Taixiang Lu
ResearchOpen Access17 Feb 2017
Scientific Reports

Volume: 7, P: 1-8
Oxidization of TGFβ-activated kinase by MPT53 is required for immunity to Mycobacterium tuberculosis

Mycobacterium tuberculosis secreted protein MPT53 mediates the activation of TAK1 and induces the host immune inflammatory response.

Lin Wang
Zhonghua Liu
Baoxue Ge
Research20 May 2019
Nature Microbiology

Volume: 4, P: 1378-1388
Correction: Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/β-catenin/PPARδ signalling

Yingyan Wang
Wen Lan
Qi Wang
Amendments and CorrectionsOpen Access27 Feb 2025
Cell Death & Disease

Volume: 16, P: 1-3
Genome assembly with in vitro proximity ligation data and whole-genome triplication in lettuce

Genome assembly for many plant species can be challenging due to large size and high repeat content. Here, the authors usein vitroproximity ligation to assemble the genome of lettuce, revealing a family-specific triplication event and providing a comprehensive reference genome for a member of the Compositae.

Sebastian Reyes-Chin-Wo
Zhiwen Wang
Richard W. Michelmore
ResearchOpen Access12 Apr 2017
Nature Communications

Volume: 8, P: 1-11
Percutaneous intervertebral bridging cementoplasty for adjacent multilevel osteoporotic thoracolumbar fractures with vertebral endplate-disc complex injury: technical note

Song Wang
Chunyan Duan
Qing Wang
ResearchOpen Access01 Sept 2020
Scientific Reports

Volume: 10, P: 1-8
Identification of a novel salt tolerance gene in wild soybean by whole-genome sequencing

The identification of genes that control economically important traits is an essential step towards crop improvement. Here the authors sequence the genome of the wild soybean and, through a combined genetic and functional approach, identify a new gene affecting salt tolerance in soybean.

Xinpeng Qi
Man-Wah Li
Hon-Ming Lam
ResearchOpen Access09 Jul 2014
Nature Communications

Volume: 5, P: 1-11
Characteristics of patients with autoimmune haemolytic anaemia secondary to lymphoproliferative disorder: A single-centre retrospective analysis

Limin Xing
Manjun Zhao
Zonghong Shao
ResearchOpen Access23 Dec 2019
Scientific Reports

Volume: 9, P: 1-7
Mitogenome types of two Lentinula edodes sensu lato populations in China

Xiaoxia Song
Yan Zhao
Ruiheng Yang
ResearchOpen Access01 Jul 2019
Scientific Reports

Volume: 9, P: 1-11
Dapagliflozin improves skeletal muscle insulin sensitivity through SIRT1 activation induced by nutrient deprivation state

Qi Gao
Yingying Jiang
Yanhui Yang
ResearchOpen Access23 Jul 2024
Scientific Reports

Volume: 14, P: 1-14
Impaired 2′,3′-cyclic phosphate tRNA repair causes thermo-sensitive genic male sterility in rice

Bin Yan
Chunyan Liu
Xiaofeng Cao
Research09 Sept 2024
Cell Research

Volume: 34, P: 763-775
Insight into wet scavenging effects on sulfur and nitrogen containing organic compounds in urban Beijing

Chunyan Zhang
Yonghong Wang
Hong He
ResearchOpen Access04 Sept 2024
npj Climate and Atmospheric Science

Volume: 7, P: 1-9
VALD-3, a Schiff base ligand synthesized from o-vanillin derivatives, induces cell cycle arrest and apoptosis in breast cancer cells by inhibiting the Wnt/β-catenin pathway

Hongling Li
Chunyan Dang
Jing Zhang
ResearchOpen Access22 Jul 2021
Scientific Reports

Volume: 11, P: 1-14
Notch1 deficiency decreases hepatic lipid accumulation by induction of fatty acid oxidation

No-Joon Song
Ui Jeong Yun
Kye Won Park
ResearchOpen Access20 Jan 2016
Scientific Reports

Volume: 6, P: 1-10
Author Correction: Numerical simulation analysis of carbon defects in the buffer on vertical leakage and breakdown of GaN on silicon epitaxial layers

Weicheng Cao
Chunyan Song
Hongyu Ji
Amendments and CorrectionsOpen Access23 Apr 2024
Scientific Reports

Volume: 14, P: 1-2
StRAP2.3, an ERF‐VII transcription factor, directly activates StInvInh2 to enhance cold-induced sweetening resistance in potato

Weiling Shi
Yuhao Song
Xun Liu
ResearchOpen Access01 Apr 2021
Horticulture Research

Volume: 8, P: 1-10
Development of the semi-dry dot-blot method for intraoperative detecting micropapillary component in lung adenocarcinoma based on proteomics analysis

Long Xu
Hang Su
Chang Chen
Research04 Apr 2023
British Journal of Cancer

Volume: 128, P: 2116-2125
Lipid levels and new-onset diabetes in a hypertensive population: the China Stroke Primary Prevention Trial

Leliang Li
Ping Li
Xiaoshu Cheng
ResearchOpen Access01 Aug 2017
Scientific Reports

Volume: 7, P: 1-12
Adjuvant trastuzumab emtansine in HER2-positive breast cancer patients with HER2-negative residual invasive disease in KATHERINE

Sibylle Loibl
Chiun-Sheng Huang
Norman Wolmark
ResearchOpen Access19 Sept 2022
npj Breast Cancer

Volume: 8, P: 1-6
Wheat growth monitoring and yield estimation based on remote sensing data assimilation into the SAFY crop growth model

Chunyan Ma
Mingxing Liu
Yilin Wang
ResearchOpen Access31 Mar 2022
Scientific Reports

Volume: 12, P: 1-16
Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1

Huan He
Dandan Song
Chunyan Zhao
Research23 Apr 2019
Oncogene

Volume: 38, P: 5725-5738
Retrospective study of budesonide in children with eosinophilic gastroenteritis

Shengbo Fang
Yanqing Song
Chunyan Li
Research29 May 2019
Pediatric Research

Volume: 86, P: 505-509
Response gene to complement 32 (RGC-32) expression on M2-polarized and tumor-associated macrophages is M-CSF-dependent and enhanced by tumor-derived IL-4

Peng Zhao
Daiqing Gao
Xun Qu
Research24 Nov 2014
Cellular & Molecular Immunology

Volume: 12, P: 692-699
External validation of a deep learning detection system for glaucomatous optic neuropathy: a real-world multicentre study

Xu Qian
Song Xian
Qu Yi
Research15 Jun 2023
Eye

Volume: 37, P: 3813-3818

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