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Showing 1–4 of 4 results
Advanced filters: Author: Clara Alsinet Clear advanced filters

  • Immune cells are under evolutionary pressure due to their anti-infective defence role. Here Salvador-Martínez and Murga-Moreno et al. combine population genetics approaches and Human Cell Atlas data, to quantify the adaptation of human immune cell types and suggest high adaptation rates in tissue-resident cells at the frontline of infections.

    • Irepan Salvador-Martínez
    • Jesus Murga-Moreno
    • Holger Heyn
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-15

  • The myeloid lineage is central to homeostasis and immunity. The authors provide an atlas of human iPSC-to-myeloid cell differentiation and demonstrate that the in vitro system recapitulates yolk sac differentiation, opening new avenues to human myelopoiesis.

    • Clara Alsinet
    • Maria Nascimento Primo
    • Roser Vento-Tormo
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-17