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Showing 301–350 of 649 results

Advanced filters: Author: D S Bae Clear advanced filters

Extracellular α-synuclein—a novel and crucial factor in Lewy body diseases

Lewy body diseases are characterized by aggregates of misfolded α-synuclein within the neuronal cytoplasm. Here, Lee and colleagues review the growing evidence that aberrant α-synuclein is released by neurons into the extracellular milieu and taken up by neighbouring neurons and microglia. They describe how this novel source of α-synuclein could be involved in the pathogenesis of Lewy body diseases, and outline potential therapeutic stratgies to target extracellular α-synuclein.

He-Jin Lee
Eun-Jin Bae
Seung-Jae Lee
Reviews28 Jan 2014
Nature Reviews Neurology

Volume: 10, P: 92-98
Ridaforolimus as a single agent in advanced endometrial cancer: results of a single-arm, phase 2 trial

N Colombo
D S McMeekin
F Haluska
ResearchOpen Access12 Feb 2013
British Journal of Cancer

Volume: 108, P: 1021-1026
Genetics of rheumatoid arthritis contributes to biology and drug discovery

A genome-wide association study meta-analysis of more than 100,000 subjects of European and Asian ancestries reveals 42 new risk loci for rheumatoid arthritis, with follow-up studies identifying 98 biological candidate genes that are either already being targeted by drugs or could be in the future.

Yukinori Okada
Di Wu
Robert M. Plenge
Research25 Dec 2013
Nature

Volume: 506, P: 376-381
Perioperative stroke

Perioperative stroke — that is stroke occurring during or within 30 days of surgery — is associated with poor outcomes. This Primer summarizes the epidemiology, mechanisms, diagnosis and treatment of perioperative stroke.

Jonathon P. Fanning
Bruce C. V. Campbell
Steven R. Messé
Reviews18 Jan 2024
Nature Reviews Disease Primers

Volume: 10, P: 1-23
Large bi-axial tensile strain effect in epitaxial BiFeO₃ film grown on single crystal PrScO₃

In-Tae Bae
Zachary R. Lingley
Hanjong Paik
ResearchOpen Access03 Nov 2023
Scientific Reports

Volume: 13, P: 1-15
Assessment of photoacoustic tomography contrast for breast tissue imaging using 3D correlative virtual histology

Gurneet S. Sangha
Bihe Hu
Craig J. Goergen
ResearchOpen Access15 Feb 2022
Scientific Reports

Volume: 12, P: 1-13
Author Correction: Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia

Xiaowei Zhu
Bo Zhou
Alexander E. Urban
Amendments and Corrections30 Aug 2023
Nature Neuroscience

Volume: 26, P: 1833
Nanometric axial resolution of fibronectin assembly units achieved with an efficient reconstruction approach for multi-angle-TIRF microscopy

Emmanuel Soubies
Agata Radwanska
Sébastien Schaub
ResearchOpen Access13 Feb 2019
Scientific Reports

Volume: 9, P: 1-10
Distinct clinical outcomes of two CIMP-positive colorectal cancer subtypes based on a revised CIMP classification system

Jeong Mo Bae
Jung Ho Kim
Gyeong Hoon Kang
ResearchOpen Access09 Mar 2017
British Journal of Cancer

Volume: 116, P: 1012-1020
The RUNX family: developmental regulators in cancer

The RUNX transcription factors seem to have dichotomous roles in cancer, sometimes being oncogenic and sometimes acting as tumour suppressors. This Review discusses the many roles of the RUNX family in cancer biology.

Yoshiaki Ito
Suk-Chul Bae
Linda Shyue Huey Chuang
Reviews16 Jan 2015
Nature Reviews Cancer

Volume: 15, P: 81-95
A highly sensitive and specific real-time quantitative polymerase chain reaction assay for Perkinsus marinus detection in oysters

Seung-Hyeon Kim
S.D.N.K. Bathige
Kyung-Il Park
ResearchOpen Access26 Oct 2024
Scientific Reports

Volume: 14, P: 1-9
Selective activation of Akt1 by mammalian target of rapamycin complex 2 regulates cancer cell migration, invasion, and metastasis

E K Kim
S J Yun
S S Bae
Research21 Feb 2011
Oncogene

Volume: 30, P: 2954-2963
The bio-barcode assay for the detection of protein and nucleic acid targets using DTT-induced ligand exchange

Haley D Hill
Chad A Mirkin
Protocols29 Jun 2006
Nature Protocols

Volume: 1, P: 324-336
The brain time toolbox, a software library to retune electrophysiology data to brain dynamics

Van Bree et al. present the Brain Time Toolbox which warps electrophysiology data in line with the brain’s dynamics. This procedure overcomes the issue that the clock time format of brain data is out of synchrony with a dynamic brain that uses its own regime of time.

Sander van Bree
María Melcón
Simon Hanslmayr
Research20 Jun 2022
Nature Human Behaviour

Volume: 6, P: 1430-1439
Predicting early mortality in hemodialysis patients: a deep learning approach using a nationwide prospective cohort in South Korea

Junhyug Noh
Sun Young Park
Kyung Don Yoo
ResearchOpen Access29 Nov 2024
Scientific Reports

Volume: 14, P: 1-11
Digenome-seq web tool for profiling CRISPR specificity

Jeongbin Park
Liam Childs
Sangsu Bae
Correspondence30 May 2017
Nature Methods

Volume: 14, P: 548-549
Computer vision for kinematic metrics of the drinking task in a pilot study of neurotypical participants

Justin Huber
Stacey Slone
Jihye Bae
ResearchOpen Access05 Sept 2024
Scientific Reports

Volume: 14, P: 1-11
Clinically differential diagnosis of human granulocytic anaplasmosis and severe fever with thrombocytopenia syndrome

Dong-Min Kim
Byung Jun Yu
Shilpa Chatterjee
ResearchOpen Access26 Apr 2023
Scientific Reports

Volume: 13, P: 1-5
Identification of the causative gene of a transparent phenotype of juvenile red sea bream Pagrus major

Eitaro Sawayama
Yoshihiro Handa
Kiyoshi Asahina
Research26 Jun 2021
Heredity

Volume: 127, P: 167-175
Functional annotation and comparative genomics analysis of Balamuthia mandrillaris reveals potential virulence-related genes

Alejandro Otero-Ruiz
Libia Zulema Rodriguez-Anaya
Abraham Cruz-Mendívil
ResearchOpen Access31 Aug 2023
Scientific Reports

Volume: 13, P: 1-10
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

Soumya Raychaudhuri, Paul de Bakker and colleagues report fine mapping of the rheumatoid arthritis associations within the MHC by combining genome-wide SNP data and imputation of classical HLA alleles and SNPs across the MHC. They identify five amino acid positions in HLA-DRβ1, HLA-B and HLA-DPβ1 that together can explain most of the MHC association to seropositive rheumatoid arthritis.

Soumya Raychaudhuri
Cynthia Sandor
Paul I W de Bakker
Research29 Jan 2012
Nature Genetics

Volume: 44, P: 291-296
Association between body mass index and three-year outcome of acute myocardial infarction

Soyoon Park
Dae-Won Kim
Jei Keon Chae
ResearchOpen Access01 Mar 2024
Scientific Reports

Volume: 14, P: 1-12
Effects of white matter hyperintensity burden on functional outcome after mild versus moderate-to-severe ischemic stroke

Dong-Seok Gwak
Wi-Sun Ryu
Dong-Eog Kim
ResearchOpen Access29 Sept 2024
Scientific Reports

Volume: 14, P: 1-11
Author Correction: The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing

Rachel E. Rodin
Yanmei Dou
Christopher A. Walsh
Amendments and Corrections22 Mar 2021
Nature Neuroscience

Volume: 24, P: 611
A review of 72 consecutive cases of Acanthamoeba keratitis, 1984–1992

A S Bacon
D G Frazer
P Wright
Research01 Nov 1993
Eye

Volume: 7, P: 719-725
Prognostic factors in metaplastic carcinoma of the breast: a multi-institutional study

E A Rakha
P H Tan
I O Ellis
ResearchOpen Access25 Nov 2014
British Journal of Cancer

Volume: 112, P: 283-289
Computed tomography porosity and spherical indentation for determining cortical bone millimetre-scale mechanical properties

Oliver R. Boughton
Shaocheng Ma
Justin P. Cobb
ResearchOpen Access15 May 2019
Scientific Reports

Volume: 9, P: 1-15
Surgical outcomes of robotic thyroidectomy for thyroid tumors over 4 cm via the bilateral axillo-breast approach

Hye Lim Bae
Junice Shi-Hui Wong
Kyu Eun Lee
ResearchOpen Access21 May 2024
Scientific Reports

Volume: 14, P: 1-9
Design principles for efficient photoelectrodes in solar rechargeable redox flow cell applications

Rational design of photoelectrodes is a key requirement to boost conversion efficiency of photoelectrochemical redox flow cells. Here, band alignment design and surface coverage control are used to design single-photon photoelectrodes that achieve 9.4% solar-to-chemical conversion efficiency.

Dowon Bae
Gerasimos Kanellos
Wilson A. Smith
ResearchOpen Access14 Apr 2020
Communications Materials

Volume: 1, P: 1-9
O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes

Seung Yoon Park
Jiwon Ryu
Wan Lee
ResearchOpen Access01 Jun 2005
Experimental & Molecular Medicine

Volume: 37, P: 220-229
Global epidemiology of rheumatoid arthritis

In this Review, the authors summarize and discuss regional differences in the prevalence and incidence of rheumatoid arthritis (RA), and describe temporal trends associated with the disease as well as evidence related to risk factors.

Axel Finckh
Benoît Gilbert
Kim Lauper
Reviews06 Sept 2022
Nature Reviews Rheumatology

Volume: 18, P: 591-602
Thermoelectric properties enhancement of p-type composite films using wood-based binder and mechanical pressing

Eunhwa Jang
Aswani Poosapati
Deepa Madan
ResearchOpen Access27 May 2019
Scientific Reports

Volume: 9, P: 1-10
Response to “Unexpected mutations after CRISPR–Cas9 editing in vivo”

Sang-Tae Kim
Jeongbin Park
Jin-Soo Kim
Correspondence30 Mar 2018
Nature Methods

Volume: 15, P: 239-240
T-regulatory cells predict clinical outcome in soft tissue sarcoma patients: a clinico-pathological study

Maria A. Smolle
Laurin Herbsthofer
Joanna Szkandera
Research14 Jun 2021
British Journal of Cancer

Volume: 125, P: 717-724
Correction to: A state-of-the-science review and guide for measuring environmental exposure biomarkers in dried blood spots

Tyler A. Jacobson
Jasdeep S. Kler
William E. Funk
Amendments and CorrectionsOpen Access02 Nov 2022
Journal of Exposure Science & Environmental Epidemiology

Volume: 33, P: 672
Self-Adaptive Spike-Time-Dependent Plasticity of Metal-Oxide Memristors

M. Prezioso
F. Merrikh Bayat
D. Strukov
ResearchOpen Access19 Feb 2016
Scientific Reports

Volume: 6, P: 1-6
Galactic Cosmic Radiation Induces Persistent Epigenome Alterations Relevant to Human Lung Cancer

E. M. Kennedy
D. R. Powell
P. M. Vertino
ResearchOpen Access30 Apr 2018
Scientific Reports

Volume: 8, P: 1-14
Prediction of the Mortality Risk in Peritoneal Dialysis Patients using Machine Learning Models: A Nation-wide Prospective Cohort in Korea

Junhyug Noh
Kyung Don Yoo
Jung Pyo Lee
ResearchOpen Access04 May 2020
Scientific Reports

Volume: 10, P: 1-11
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer

Paul Brennan and colleagues perform genome-wide association analysis for oral cavity and pharyngeal cancer in trans-ancestry populations. They find seven new loci across different cancer subtypes, including a protective association in the HLA region that has a stronger effect in patients with human papillomavirus–positive cancers.

Corina Lesseur
Brenda Diergaarde
Paul Brennan
Research17 Oct 2016
Nature Genetics

Volume: 48, P: 1544-1550
Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status

R A Bras-Gonçalves
C Rosty
M-F Poupon
ResearchOpen Access20 Jan 2000
British Journal of Cancer

Volume: 82, P: 913-923
KAGRA: 2.5 generation interferometric gravitational wave detector

KAGRA is a new gravitational wave detector being built in Japan. Unlike LIGO/Virgo, it will operate at cryogenic temperatures with sapphire mirrors. KAGRA will help improve the localization of gravitational wave detections and determination of the source parameters.

T. Akutsu
M. Ando
Z.-H. Zhu
Reviews08 Jan 2019
Nature Astronomy

Volume: 3, P: 35-40
Induction of CD95 ligand and apoptosis by doxorubicin is modulated by the redox state in chemosensitive- and drug-resistant tumor cells

Claudia Friesen
Simone Fulda
Klaus-Michael Debatin
Research17 May 1999
Cell Death & Differentiation

Volume: 6, P: 471-480
Stress and mTORture signaling

J H Reiling
D M Sabatini
Reviews16 Oct 2006
Oncogene

Volume: 25, P: 6373-6383
Fusible, Elastic, and Biodegradable Polyesters of 2-Pyrone-4,6-Dicarboxylic Acid (PDC)

Tsuyoshi Michinobu
Masami Bito
Kiyotaka Shigehara
Research09 Oct 2009
Polymer Journal

Volume: 41, P: 1111-1116
Effect of positive pressure ventilation and bariatric surgery on extracellular vesicle microRNAs in patients with severe obesity and obstructive sleep apnea

J. Lázaro
D. Sanz-Rubio
J. M. Marin
Research25 Oct 2022
International Journal of Obesity

Volume: 47, P: 24-32
The proliferation-associated early response gene p22/PRG1 is a novel p53 target gene

Heiner Schäfer
Anna Trauzold
Wolfgang E Schmidt
Research02 Jun 1998
Oncogene

Volume: 16, P: 2479-2487
Stochastic anomaly of methylome but persistent SRY hypermethylation in disorder of sex development in canine somatic cell nuclear transfer

Young-Hee Jeong
Hanlin Lu
Fei Gao
ResearchOpen Access09 Aug 2016
Scientific Reports

Volume: 6, P: 1-11
CCL2 deficient mesenchymal stem cells fail to establish long-lasting contact with T cells and no longer ameliorate lupus symptoms

Hong Kyung Lee
Hyung Sook Kim
Sang-Bae Han
ResearchOpen Access24 Jan 2017
Scientific Reports

Volume: 7, P: 1-12
Drug-coated balloon versus drug-eluting stent for femoropopliteal total occlusions: intraluminal versus subintimal approaches

Yong Hoon Kim
Ae-Young Her
Hyun-Sook Kim
ResearchOpen Access11 Sept 2024
Scientific Reports

Volume: 14, P: 1-11
BMS794833 inhibits macrophage efferocytosis by directly binding to MERTK and inhibiting its activity

Seung-Hyun Bae
Jung-Hoon Kim
Hyonchol Jang
ResearchOpen Access02 Sept 2022
Experimental & Molecular Medicine

Volume: 54, P: 1450-1460

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