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Showing 1–3 of 3 results
Advanced filters: Author: Darci Phillips Clear advanced filters

  • PD-1 blockade is effective for only a subset of patients with cutaneous T cell lymphomas. Here, the authors report a spatial biomarker that uses immune and cancer cell topography to predict response to PD-1 blockade in this disease.

    • Darci Phillips
    • Magdalena Matusiak
    • Garry P. Nolan
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-18

  • Emerging high-plex imaging technologies are limited in resolving subcellular biomolecular features. Here, the authors propose a spatial histopathology tool that allows for high-plex protein staining and physical expansion, while retaining the lateral tissue expansion.

    • Yunhao Bai
    • Bokai Zhu
    • Sizun Jiang
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18

  • This protocol describes co-detection by indexing, a highly multiplexed imaging technology that uses DNA-conjugated antibodies to image up to 60 markers in formalin-fixed, paraffin-embedded and fresh-frozen tissues.

    • Sarah Black
    • Darci Phillips
    • Garry P. Nolan
    Protocols
    Nature Protocols
    Volume: 16, P: 3802-3835