IBS is the most common brain–gut disorder and a major cause of chronic abdominal pain. Here, Mayer and colleagues describe the key components of the gut–brain–microbiota axis in IBS and present a systems-based view of how these components interact to integrate the central, peripheral and behavioural IBS-related alterations.
- Emeran A. Mayer
- Jennifer S. Labus
- Pierre Baldi
