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Showing 1–4 of 4 results

Advanced filters: Author: Deepanjan Paul Clear advanced filters

PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics

Francisella novicida Cas9 (FnCas9) has low cellular editing ability which limits its therapeutic utilities. Here, the authors rationally engineer the protein to develop enhanced FnCas9 (enFnCas9) variants with high on-target editing efficiency, high precision, broadened target range, and flexible base editing outcomes.

Sundaram Acharya
Asgar Hussain Ansari
Debojyoti Chakraborty
ResearchOpen Access28 Jun 2024
Nature Communications

Volume: 15, P: 1-23
A-to-I editing in human miRNAs is enriched in seed sequence, influenced by sequence contexts and significantly hypoedited in glioblastoma multiforme

Deepanjan Paul
Ashis Narayan Sinha
Arijit Mukhopadhyay
ResearchOpen Access26 May 2017
Scientific Reports

Volume: 7, P: 1-12
Fusion transcripts in normal human cortex increase with age and show distinct genomic features for single cells and tissues

Bharati Mehani
Kiran Narta
Arijit Mukhopadhyay
ResearchOpen Access28 Jan 2020
Scientific Reports

Volume: 10, P: 1-12
Novel internal regulators and candidate miRNAs within miR-379/miR-656 miRNA cluster can alter cellular phenotype of human glioblastoma

Subhashree Nayak
Meghali Aich
Chitra Sarkar
ResearchOpen Access16 May 2018
Scientific Reports

Volume: 8, P: 1-10

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