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Showing 1–7 of 7 results
Advanced filters: Author: Deepta Bhattacharya Clear advanced filters

  • Terminally differentiated plasma cells reside in multiple tissues to contribute to local immunity. Nutt and colleagues examined tissue-specific differences in long-lived plasma cell lifespan and function, identifying unique transcriptional attributes in addition to the core plasma cell program.

    • Julie Tellier
    • Ilariya Tarasova
    • Stephen L. Nutt
    Research
    Nature Immunology
    Volume: 25, P: 330-342

  • mRNA-based SARS-CoV-2 vaccines can induce protective immunity in older individuals, but whether they encompass new variants is not clear. Here the authors assess mRNA vaccine responses in both younger (<50) and older (>55) cohorts to find slightly delayed humoral and cellular immunity in the latter but, more importantly, reactivity to multiple variants.

    (I understand an eTOC summary is provided, but unfortunately it does not conform with our format.)

    • Mladen Jergović
    • Jennifer L. Uhrlaub
    • Janko Nikolich-Žugich
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-8

  • Emerging evidence shows that boosting with updated mRNA vaccines that target SARS-CoV-2 variants stimulates better neutralizing antibody responses than homologous boosters.

    • Deepta Bhattacharya
    • Gabriel D. Victora
    News & Views
    Nature Medicine
    Volume: 28, P: 2257-2258

  • Chronic viral infections can trigger ineffective antibody responses. A new study shows that deletion of B cell-specific Moloney murine leukemia virus integration site 1 (BMI-1) from B cells restores protective antibodies during chronic infection.

    • Tyler J. Ripperger
    • Deepta Bhattacharya
    News & Views
    Nature Immunology
    Volume: 23, P: 6-8