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Menin inhibitor MI-503 exhibits potent anti-cancer activity in osteosarcoma

Shen Tian
Zhuang-Yu Hao
Yi Zhang
ResearchOpen Access27 Feb 2025
Scientific Reports

Volume: 15, P: 1-9
Circ-0075305 hinders gastric cancer stem cells by indirectly disrupting TCF4–β-catenin complex and downregulation of SOX9

Circular RNA Circ0075305 hinders gastric cancer stem cells by indirectly increasing the expression of RPRD1A. In turn, RPRD1A disrupts TCF4-β-catenin complex formation and promotes downregulation of SOX9 transcription.

Qi-Yue Chen
Kai-Xiang Xu
Chang-Ming Huang
ResearchOpen Access07 May 2024
Communications Biology

Volume: 7, P: 1-16

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Menin inhibitor MI-503 exhibits potent anti-cancer activity in osteosarcoma

Circ-0075305 hinders gastric cancer stem cells by indirectly disrupting TCF4–β-catenin complex and downregulation of SOX9

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