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Comparative genomics of the major parasitic worms

Comparative study of 81 genomes of parasitic and non-parasitic worms identifies gene family births and expanded gene families at key nodes in the phylogeny that are relevant to parasitism and proteins historically targeted for drug development.

Avril Coghlan
Rahul Tyagi
Matthew Berriman
ResearchOpen Access05 Nov 2018
Nature Genetics

Volume: 51, P: 163-174
Profiling microRNAs through development of the parasitic nematode Haemonchus identifies nematode-specific miRNAs that suppress larval development

Neil D. Marks
Alan D. Winter
Collette Britton
ResearchOpen Access26 Nov 2019
Scientific Reports

Volume: 9, P: 1-15
Genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm

Stephen Doyle et al. report the chromosome-scale genome assembly and transcriptome sequence data of Haemonchus contortus, a key parasitic nematode model. These data show nearly complete conservation of chromosome content with C. elegans and brings insight into transcriptional regulation and chromosome-wide genetic diversity in this important pathogen.

Stephen R. Doyle
Alan Tracey
James A. Cotton
ResearchOpen Access09 Nov 2020
Communications Biology

Volume: 3, P: 1-16

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