Nature Search

Nanofabrication of silk microneedles for high-throughput micronutrient delivery and continuous sap monitoring in plants

Porous and hollow silk fibroin microneedles nanofabricated with phase front assembly allow the authors to establish a prolonged interface with plants for delivery of micronutrients, crop fortification and continuous plant health monitoring.

Yunteng Cao
Doyoon Kim
Benedetto Marelli
Research29 Apr 2025
Nature Nanotechnology

P: 1-10
Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipids

Amy R. Bentley
Michael R. Brown
Ervin R. Fox
ResearchOpen Access20 Jun 2025
Translational Psychiatry

Volume: 15, P: 1-12
Publisher Correction: Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors

Huipeng Li
Elise T. Courtois
Shyam Prabhakar
Amendments and Corrections19 Dec 2022
Nature Genetics

Volume: 55, P: 166
PDLIM5 is not a neuronal CaV2.2 adaptor protein

Sabiha R Gardezi
Alexander M Weber
Elise F Stanley
Correspondence01 Aug 2009
Nature Neuroscience

Volume: 12, P: 957-958
Macrophage-associated wound healing contributes to African green monkey SIV pathogenesis control

Here, the authors compare gene expression signatures in rectal tissues of African green monkeys (AGMs) and rhesus macaques (RMs) acutely infected with simian immunodeficiency virus and find that AGMs rapidly activate and maintain evolutionarily conserved regenerative wound healing mechanisms.

Fredrik Barrenas
Kevin Raehtz
Michael Gale Jr
ResearchOpen Access08 Nov 2019
Nature Communications

Volume: 10, P: 1-15
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

A meta-analysis of genome-wide association studies across different populations highlights new risk loci and provides a genetic risk score that can stratify prostate cancer risk across ancestries.

David V. Conti
Burcu F. Darst
Christopher A. Haiman
Research04 Jan 2021
Nature Genetics

Volume: 53, P: 65-75
Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

A multi-ancestry genome-wide gene–smoking interaction study identifies 13 new loci associated with serum lipids.

Amy R. Bentley
Yun J. Sung
L. Adrienne Cupples
Research29 Mar 2019
Nature Genetics

Volume: 51, P: 636-648
Identifying biomarkers of sheep welfare using a metabolic discrepancy model

Sarah Babington
Luoyang Ding
Dominique Blache
ResearchOpen Access17 Apr 2025
Scientific Reports

Volume: 15, P: 1-18
MYTHO is a novel regulator of skeletal muscle autophagy and integrity

Here, the authors identify a novel regulator of autophagy, skeletal muscle mass and integrity named MYTHO. Silencing MYTHO protects against muscle atrophy in a wide range of acute catabolic conditions, while prolonged silencing causes a severe myopathy.

Jean-Philippe Leduc-Gaudet
Anais Franco-Romero
Gilles Gouspillou
ResearchOpen Access02 Mar 2023
Nature Communications

Volume: 14, P: 1-20
Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors

Shyam Prabhakar, Paul Robson, Iain Beehuat Tan and colleagues characterize the cellular heterogeneity of colorectal tumors and their microenvironment on the basis of single-cell RNA–seq data analyzed with their newly developed clustering algorithm, reference component analysis (RCA). Their analyses identify two subtypes of cancer-associated fibroblasts and further divide tumors into subgroups with divergent survival probabilities.

Huipeng Li
Elise T Courtois
Shyam Prabhakar
Research20 Mar 2017
Nature Genetics

Volume: 49, P: 708-718
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

Genome-wide association studies (GWAS) have become a key tool to discover genetic markers for complex traits; however, environmental factors that interact with genes are rarely considered. Here, the authors conduct a GWAS of obesity traits, and find that smoking may alter genetic susceptibilities.

Anne E. Justice
Thomas W. Winkler
L Adrienne Cupples
ResearchOpen Access26 Apr 2017
Nature Communications

Volume: 8, P: 1-19
Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

Sleep duration is associated with an adverse lipid profile. Here, the authors perform genome-wide gene-by-sleep interaction analysis and find 49 previously unreported lipid loci when considering short or long total sleep time.

Raymond Noordam
Maxime M. Bos
Susan Redline
ResearchOpen Access12 Nov 2019
Nature Communications

Volume: 10, P: 1-13
A multimodal cell census and atlas of the mammalian primary motor cortex

The BRAIN Initiative Cell Census Network has constructed a multimodal cell census and atlas of the mammalian primary motor cortex in a landmark effort towards understanding brain cell-type diversity, neural circuit organization and brain function.

Edward M. Callaway
Hong-Wei Dong
Susan Sunkin
ResearchOpen Access06 Oct 2021
Nature

Volume: 598, P: 86-102
Variability in the analysis of a single neuroimaging dataset by many teams

The results obtained by seventy different teams analysing the same functional magnetic resonance imaging dataset show substantial variation, highlighting the influence of analytical choices and the importance of sharing workflows publicly and performing multiple analyses.

Rotem Botvinik-Nezer
Felix Holzmeister
Tom Schonberg
Research20 May 2020
Nature

Volume: 582, P: 84-88
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

Multi-ancestry genome-wide association analyses and systematic variant-to-gene mapping strategies implicate new genes and pathways influencing lung function and chronic obstructive pulmonary disease risk.

Nick Shrine
Abril G. Izquierdo
Martin D. Tobin
ResearchOpen Access13 Mar 2023
Nature Genetics

Volume: 55, P: 410-422
Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data

Analysis of whole-genome sequences of 25,465 individuals of European ancestry shows that rare variants contribute substantially to the heritability of height and body mass index.

Pierrick Wainschtein
Deepti Jain
Peter M. Visscher
Research07 Mar 2022
Nature Genetics

Volume: 54, P: 263-273
Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants

A multi-ancestry genome-wide association study of prostate cancer performed in 156,319 cases and 788,443 controls identifies 187 novel risk variants associated with the disease. Genetic risk scores associated with overall risk, and risk of aggressive disease in men of African ancestry.

Anqi Wang
Jiayi Shen
Christopher A. Haiman
Research09 Nov 2023
Nature Genetics

Volume: 55, P: 2065-2074
Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab

Vaccination is effective in protecting from COVID-19. Here the authors report immune responses and breakthrough infections in twice-vaccinated patients receiving anti-TNF treatments for inflammatory bowel disease, and find dampened vaccine responses that implicate the need of adapted vaccination schedules for these patients.

Simeng Lin
Nicholas A. Kennedy
Jeannie Bishop
ResearchOpen Access16 Mar 2022
Nature Communications

Volume: 13, P: 1-14
Cellular anatomy of the mouse primary motor cortex

Multi-modal analysis is used to generate a 3D atlas of the upper limb area of the mouse primary motor cortex, providing a framework for future studies of motor control circuitry.

Rodrigo Muñoz-Castañeda
Brian Zingg
Hong-Wei Dong
ResearchOpen Access06 Oct 2021
Nature

Volume: 598, P: 159-166
Author Correction: Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors

Huipeng Li
Elise T Courtois
Shyam Prabhakar
Amendments and Corrections12 Nov 2018
Nature Genetics

Volume: 50, P: 1754
Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy

UDP-glucuronic acid is a component of the extracellular matrix. Here, the authors report biallelic variants in the gene encoding UDP-Glucose 6-Dehydrogenase (UGDH) in individuals affected by developmental epileptic encephalopathies that impair UGDH stability, oligomerization, or enzymatic activity in vitro.

Holger Hengel
Célia Bosso-Lefèvre
Bruno Reversade
ResearchOpen Access30 Jan 2020
Nature Communications

Volume: 11, P: 1-16
Author Correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

Nick Shrine
Abril G. Izquierdo
Martin D. Tobin
Amendments and CorrectionsOpen Access25 Sept 2023
Nature Genetics

Volume: 55, P: 1778-1779
CHD3 helicase ___domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language

Chromodomain Helicase DNA-binding (CHD) proteins have been implicated in neurodevelopmental processes. Here, the authors identify missense variants in CHD3 that disturb its chromatin remodeling activities and cause a neurodevelopmental disorder with macrocephaly and speech and language impairment.

Lot Snijders Blok
Justine Rousseau
Philippe M. Campeau
ResearchOpen Access05 Nov 2018
Nature Communications

Volume: 9, P: 1-12
Near full length genome of a recombinant (E/D) cosavirus strain from a rural area in the central region of Brazil

Antonio Charlys da Costa
Adriana Luchs
Élcio Leal
ResearchOpen Access17 Aug 2018
Scientific Reports

Volume: 8, P: 1-5
Cell intercalation from top to bottom

The mechanisms that drive cell intercalation and thereby cell rearrangements during morphogenesis vary in different developmental contexts and species. Comparison of the key control steps in each case has improved our understanding of the specific parts played by adhesion and cytoskeletal changes, as well as planar cell polarity signalling.

Elise Walck-Shannon
Jeff Hardin
Reviews20 Dec 2013
Nature Reviews Molecular Cell Biology

Volume: 15, P: 34-48
Author Correction: CHD3 helicase ___domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language

Lot Snijders Blok
Justine Rousseau
Philippe M. Campeau
Amendments and CorrectionsOpen Access15 Feb 2019
Nature Communications

Volume: 10, P: 1-4
Author Correction: CHD3 helicase ___domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language

Lot Snijders Blok
Justine Rousseau
Philippe M. Campeau
Amendments and CorrectionsOpen Access02 May 2019
Nature Communications

Volume: 10, P: 1-4
White Matter Integrity is Associated with Treatment Outcome Measures in Cocaine Dependence

Jiansong Xu
Elise E DeVito
Marc N Potenza
Research10 Mar 2010
Neuropsychopharmacology

Volume: 35, P: 1541-1549
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

David V. Conti
Burcu F. Darst
Christopher A. Haiman
Amendments and Corrections20 Jan 2021
Nature Genetics

Volume: 53, P: 413
Transcriptional cooperation of PBX1 and PAX6 in adult neural progenitor cells

Ann-Christin Hau
Elise Mommaerts
Dorothea Schulte
ResearchOpen Access25 Oct 2021
Scientific Reports

Volume: 11, P: 1-12
Effect of balloon atrial septostomy on cerebral oxygenation in neonates with transposition of the great arteries

Michelle E. van der Laan
Elise A. Verhagen
Elisabeth M.W. Kooi
Research24 Oct 2012
Pediatric Research

Volume: 73, P: 62-67
Transcriptional Analysis of The Adaptive Digestive System of The Migratory Locust in Response to Plant Defensive Protease Inhibitors

Jornt Spit
Michiel Holtof
Jozef Vanden Broeck
ResearchOpen Access01 Sept 2016
Scientific Reports

Volume: 6, P: 1-15
Multi-ancestry genome-wide gene–sleep interactions identify novel loci for blood pressure

Heming Wang
Raymond Noordam
Diana van Heemst
Research15 Apr 2021
Molecular Psychiatry

Volume: 26, P: 6293-6304
Four consecutive yearly point-prevalence studies in Wales indicate lack of improvement in sepsis care on the wards

Maja Kopczynska
Harry Unwin
Judith E. Hall
ResearchOpen Access10 Aug 2021
Scientific Reports

Volume: 11, P: 1-12
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Ali Abbas
Sheryl Ann Abdukahil
Luis Felipe Reyes
ResearchOpen Access30 Jul 2022
Scientific Data

Volume: 9, P: 1-22

Search

Nanofabrication of silk microneedles for high-throughput micronutrient delivery and continuous sap monitoring in plants

Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipids

Publisher Correction: Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors

PDLIM5 is not a neuronal CaV2.2 adaptor protein

Macrophage-associated wound healing contributes to African green monkey SIV pathogenesis control

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

Identifying biomarkers of sheep welfare using a metabolic discrepancy model

MYTHO is a novel regulator of skeletal muscle autophagy and integrity

Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

A multimodal cell census and atlas of the mammalian primary motor cortex

Variability in the analysis of a single neuroimaging dataset by many teams

Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data

Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants

Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab

Cellular anatomy of the mouse primary motor cortex

Author Correction: Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors

Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy

Author Correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

CHD3 helicase ___domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language

Near full length genome of a recombinant (E/D) cosavirus strain from a rural area in the central region of Brazil

Cell intercalation from top to bottom

Author Correction: CHD3 helicase ___domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language

Author Correction: CHD3 helicase ___domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language

White Matter Integrity is Associated with Treatment Outcome Measures in Cocaine Dependence

At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

Transcriptional cooperation of PBX1 and PAX6 in adult neural progenitor cells

Effect of balloon atrial septostomy on cerebral oxygenation in neonates with transposition of the great arteries

Transcriptional Analysis of The Adaptive Digestive System of The Migratory Locust in Response to Plant Defensive Protease Inhibitors

Multi-ancestry genome-wide gene–sleep interactions identify novel loci for blood pressure

Four consecutive yearly point-prevalence studies in Wales indicate lack of improvement in sepsis care on the wards

ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

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