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  • Moliner et al. show that psychedelics directly bind to the BDNF receptor TrkB with high affinity and promote BDNF-mediated plasticity and antidepressant-like effects, whereas their hallucinogenic-like effects are independent of TrkB binding.

    • Rafael Moliner
    • Mykhailo Girych
    • Eero Castrén
    ResearchOpen Access
    Nature Neuroscience
    Volume: 26, P: 1032-1041