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Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair

Here the authors describe a functional screening platform in human stem cells to identify and optimize protein-based gene editing additives that increase homologous directed recombination and have potential to improve gene therapy workflows.

Juan A. Perez-Bermejo
Oghene Efagene
Kristen L. Seim
ResearchOpen Access23 Mar 2024
Nature Communications

Volume: 15, P: 1-16

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Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair

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