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Showing 1–25 of 25 results
Advanced filters: Author: Erik Storrs Clear advanced filters
  • Complete sequences of chromosomes telomere-to-telomere from chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan and siamang provide a comprehensive and valuable resource for future evolutionary comparisons.

    • DongAhn Yoo
    • Arang Rhie
    • Evan E. Eichler
    ResearchOpen Access
    Nature
    Volume: 641, P: 401-418
  • Visium spatial transcriptomics, single-nucleus RNA sequencing and co-detection by indexing are used to identify distinct spatial microregions in tumours and their microenvironment across six diverse solid cancer types.

    • Chia-Kuei Mo
    • Jingxian Liu
    • Li Ding
    ResearchOpen Access
    Nature
    Volume: 634, P: 1178-1186
  • We present the complete 62,460,029-base-pair sequence of a human Y chromosome from the HG002 genome (T2T-Y) that corrects multiple errors in GRCh38-Y and adds over 30 million base pairs of sequence to the reference.

    • Arang Rhie
    • Sergey Nurk
    • Adam M. Phillippy
    Research
    Nature
    Volume: 621, P: 344-354
  • A multi-omic analysis of pancreatic cancer identifies spatially resolved, heterogeneous cell populations including transitional cell types. Analysis of primary samples identifies treatment-related changes in cross-talk between tumor and stromal cells.

    • Daniel Cui Zhou
    • Reyka G. Jayasinghe
    • Li Ding
    ResearchOpen Access
    Nature Genetics
    Volume: 54, P: 1390-1405
  • Two below-threshold surface code memories on superconducting processors markedly reduce logical error rates, achieving high efficiency and real-time decoding, indicating potential for practical large-scale fault-tolerant quantum algorithms.

    • Rajeev Acharya
    • Dmitry A. Abanin
    • Nicholas Zobrist
    ResearchOpen Access
    Nature
    Volume: 638, P: 920-926
  • Time-resolved measurements of the X-ray photoemission delay of core-level electrons using attosecond soft X-ray pulses from a free-electron laser can be used to determine the complex correlated dynamics of photoionization.

    • Taran Driver
    • Miles Mountney
    • James P. Cryan
    Research
    Nature
    Volume: 632, P: 762-767
  • This ancient and hostile ecosystem hosts a surprising variety of microbial organisms.

    • Linda A. Amaral Zettler
    • Felipe Gómez
    • Mitchell L. Sogin
    Research
    Nature
    Volume: 417, P: 137
  • Clonal evolution in multiple myeloma (MM) needs to be understood in both the tumor and its microenvironment. Here the authors perform single-cell multi-omics profiling of samples from MM patients at different stages, finding transitions in the immune cell composition throughout progression.

    • Ruiyang Liu
    • Qingsong Gao
    • Li Ding
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-18
  • A computational approach to generate reference-free protein families from the sequence space in metagenomes reveals an enormously diverse functional space.

    • Georgios A. Pavlopoulos
    • Fotis A. Baltoumas
    • Nikos C. Kyrpides
    ResearchOpen Access
    Nature
    Volume: 622, P: 594-602
  • Correlational selection is selection on the basis of combinations of traits. This Review demonstrates how considering correlational selection through a genomics lens will enhance integration of evolutionary research in different fields.

    • Erik I. Svensson
    • Stevan J. Arnold
    • Anna Runemark
    Reviews
    Nature Ecology & Evolution
    Volume: 5, P: 562-573
  • Statistical analysis of velocity fluctuations in the interstellar medium (ISM) of the Milky Way and NGC 4321 show that the motion of molecular gas over scales ranging from 0.1 to 1,000 pc is similar, and consistent with that generated by a combination of gravity and turbulence. ISM structure at one scale is therefore linked to structure at other scales.

    • Jonathan D. Henshaw
    • J. M. Diederik Kruijssen
    • Jiayi Sun
    Research
    Nature Astronomy
    Volume: 4, P: 1064-1071
  • A varied repertoire of responses helps manage fluctuations, as in markets. This Perspective argues that society needs to strengthen the diversity of options for responding to disruptions, exploring how this response diversity is expressed, how it can be built and lost, and what we can do to promote it.

    • Brian Walker
    • Anne-Sophie Crépin
    • Jeffrey R. Vincent
    Reviews
    Nature Sustainability
    Volume: 6, P: 621-629
  • In response to recommendations to redefine statistical significance to P ≤ 0.005, we propose that researchers should transparently report and justify all choices they make when designing a study, including the alpha level.

    • Daniel Lakens
    • Federico G. Adolfi
    • Rolf A. Zwaan
    Comments & Opinion
    Nature Human Behaviour
    Volume: 2, P: 168-171
  • The imminent release of tissue atlases combining multichannel microscopy with single-cell sequencing and other omics data from normal and diseased specimens creates an urgent need for data and metadata standards to guide data deposition, curation and release. We describe a Minimum Information about Highly Multiplexed Tissue Imaging (MITI) standard that applies best practices developed for genomics and for other microscopy data to highly multiplexed tissue images and traditional histology.

    • Denis Schapiro
    • Clarence Yapp
    • Peter K. Sorger
    Comments & Opinion
    Nature Methods
    Volume: 19, P: 262-267
  • Incompatible data storage formats have hindered the sharing and analyses of digital representations of biological pathways. BioPAX is a standardized language supported by >40 databases and software tools for exchanging pathway data.

    • Emek Demir
    • Michael P Cary
    • Gary D Bader
    Reviews
    Nature Biotechnology
    Volume: 28, P: 935-942
  • Oita, Arnold and colleagues investigate the interplay between abiotic and biotic factors in lowland forest microbial communities. Their results indicate that endophyte richness negatively correlates with temperature seasonality. Both biotic and abiotic factors should be considered when studying endophyte community diversity drivers.

    • Shuzo Oita
    • Alicia Ibáñez
    • A. Elizabeth Arnold
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-11