Nature Search

Evaluating analytic strategies to obtain high-resolution, vertex-level measures of cortical neuroanatomy in children in low- and middle-income countries

Study in children in LMIC evaluates analytic strategies to obtain high-resolution, vertex-level measures of cortical neuroanatomy using low-field magnetic resonance imaging.

Charlotte M. Pretzsch
František Váša
Christine Ecker
ResearchOpen Access12 Jun 2025
Communications Biology

Volume: 8, P: 1-14
A multimodal neural signature of face processing in autism within the fusiform gyrus

The authors leveraged a large multimodal sample and combined normative modeling and linked independent component analysis to study a cross-modal signature of face processing within the fusiform gyrus in autism.

Dorothea L. Floris
Alberto Llera
Nicolas Langer
ResearchOpen Access02 Jan 2025
Nature Mental Health

Volume: 3, P: 31-45
Genome-wide association analysis identifies six new loci associated with forced vital capacity

Stephanie London, Martin Tobin and colleagues report meta-analyses of genome-wide association studies for forced vital capacity (FVC), a spirometric measure of pulmonary function that reflects lung volume. They identify six regions newly associated with FVC and demonstrate that candidate genes at these loci are expressed in lung tissue and primary lung cells.

Daan W Loth
María Soler Artigas
Stephanie J London
Research15 Jun 2014
Nature Genetics

Volume: 46, P: 669-677
Identification and validation of biomarkers for autism spectrum disorders

Eva Loth
Will Spooren
Declan G. M. Murphy
Correspondence31 Dec 2015
Nature Reviews Drug Discovery

Volume: 15, P: 70
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

Martin Tobin and colleagues report a meta-analysis of 23 genome-wide association studies for pulmonary function. They identify 16 loci newly associated with variation in two cross-sectional measures of lung function, used to define airway obstruction and to grade the severity of obstruction.

María Soler Artigas
Daan W Loth
Martin D Tobin
Research25 Sept 2011
Nature Genetics

Volume: 43, P: 1082-1090
Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

Genome-wide analysis of chronic obstructive pulmonary disease identifies 82 loci, 35 of which are new. Integration of gene expression and genomic annotation data shows enrichment of signals in lung tissue, smooth muscle and several lung cell types.

Phuwanat Sakornsakolpat
Dmitry Prokopenko
Loems Zeigler-Heitbrock
Research25 Feb 2019
Nature Genetics

Volume: 51, P: 494-505
Fine-grained topographic organization within somatosensory cortex during resting-state and emotional face-matching task and its association with ASD traits

Christina Isakoglou
Koen V. Haak
Christian F. Beckmann
ResearchOpen Access27 Jul 2023
Translational Psychiatry

Volume: 13, P: 1-10
Adolescent impulsivity phenotypes characterized by distinct brain networks

Impulsivity is a multi-dimensional construct, and it is plausible that distinct brain networks contribute to its different aspects. Here the authors identify distinct cortical and subcortical networks underlying cognitive, clinical and genetic dimensions of impulsivity in a large sample of adolescents.

Robert Whelan
Patricia J Conrod
Hugh Garavan
Research29 Apr 2012
Nature Neuroscience

Volume: 15, P: 920-925
Identification of common variants associated with human hippocampal and intracranial volumes

Paul Thompson and colleagues report a genome-wide association study for hippocampal, intracranial and total brain volume. They identify a locus at 12q24 associated with hippocampal volume and a locus at 12q14 associated with intracranial volume.

Jason L Stein
Sarah E Medland
Paul M Thompson
Research15 Apr 2012
Nature Genetics

Volume: 44, P: 552-561
Imbalanced social-communicative and restricted repetitive behavior subtypes of autism spectrum disorder exhibit different neural circuitry

Natasha Bertelsen et al. develop a computational model to categorize patients with autism spectrum disorder (ASD) into distinct subgroups, based on social-communicative or restricted repetitive behaviors. By integrating publicly available neuroimaging and genetic data, they report neural and molecular signatures in two of these subgroups, altogether highlighting subtle differences in neural circuitry and genomic networks that could underlie phenotypic differences among ASD patients.

Natasha Bertelsen
Isotta Landi
Michael V. Lombardo
ResearchOpen Access14 May 2021
Communications Biology

Volume: 4, P: 1-13
Advances in the identification and validation of autism biomarkers

A decade on from the launch of the pioneering autism biomarker discovery initiative EU-AIMS, here we highlight advances in biomarker discovery and validation from the follow-on AIMS-2-TRIALS programme, which aims to improve the wellbeing and outcomes of autistic people through precision healthcare approaches.

Bethany F. M. Oakley
Eva Loth
Declan G. Murphy
Comments & Opinion25 Aug 2022
Nature Reviews Drug Discovery

Volume: 21, P: 697-698
Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome

In this Review, a group of experts in fragile X syndrome analyses why the considerable drug development effort based on robust preclinical findings describing the mechanisms underlying this neurodevelopmental disorder has failed to translate into effective treatment and offers possible solutions to improve clinical trial design and therapeutic approaches.

Elizabeth M. Berry-Kravis
Lothar Lindemann
Sébastien Jacquemont
Reviews08 Dec 2017
Nature Reviews Drug Discovery

Volume: 17, P: 280-299
Genetic correlates of phenotypic heterogeneity in autism

Comprehensive factor analysis of core diagnostic features provides insights into the complex genetic architecture underlying phenotypic heterogeneity in autism.

Varun Warrier
Xinhe Zhang
Simon Baron-Cohen
ResearchOpen Access02 Jun 2022
Nature Genetics

Volume: 54, P: 1293-1304
Sex differences in social brain neural responses in autism: temporal profiles of configural face-processing within data-driven time windows

Teresa Del Bianco
Meng-Chuan Lai
Thomas Bourgeron
ResearchOpen Access18 Jun 2024
Scientific Reports

Volume: 14, P: 1-15
Genetic risk for schizophrenia and autism, social impairment and developmental pathways to psychosis

Eva Velthorst
Sean Froudist-Walsh
Abraham Reichenberg
ResearchOpen Access26 Sept 2018
Translational Psychiatry

Volume: 8, P: 1-11
A human leukocyte antigen imputation study uncovers possible genetic interplay between gut inflammatory processes and autism spectrum disorders

Laura Lombardi
Sigrid Le Clerc
Ryad Tamouza
ResearchOpen Access06 Jul 2023
Translational Psychiatry

Volume: 13, P: 1-13
Cross-sectional and longitudinal neuroanatomical profiles of distinct clinical (adaptive) outcomes in autism

Charlotte M. Pretzsch
Dorothea L. Floris
Christine Ecker
ResearchOpen Access29 Mar 2023
Molecular Psychiatry

Volume: 28, P: 2158-2169
Excitatory/inhibitory imbalance in autism: the role of glutamate and GABA gene-sets in symptoms and cortical brain structure

Viola Hollestein
Geert Poelmans
Jilly Naaijen
ResearchOpen Access21 Jan 2023
Translational Psychiatry

Volume: 13, P: 1-9
Fractionating autism based on neuroanatomical normative modeling

Mariam Zabihi
Dorothea L. Floris
Andre Marquand
ResearchOpen Access06 Nov 2020
Translational Psychiatry

Volume: 10, P: 1-10
The IMAGEN study: a decade of imaging genetics in adolescents

Lea Mascarell Maričić
Henrik Walter
Amir Tahmasebi
ReviewsOpen Access29 Jun 2020
Molecular Psychiatry

Volume: 25, P: 2648-2671
Differential predictors for alcohol use in adolescents as a function of familial risk

Mira Tschorn
Robert C. Lorenz
Amir Tahmasebi
ResearchOpen Access04 Mar 2021
Translational Psychiatry

Volume: 11, P: 1-11
Sex Differences in COMT Polymorphism Effects on Prefrontal Inhibitory Control in Adolescence

Thomas P White
Eva Loth
Gunter Schumann
Research13 May 2014
Neuropsychopharmacology

Volume: 39, P: 2560-2569
Aversive Learning in Adolescents: Modulation by Amygdala–Prefrontal and Amygdala–Hippocampal Connectivity and Neuroticism

Jelka Tzschoppe
Frauke Nees
Herta Flor
Research15 Oct 2013
Neuropsychopharmacology

Volume: 39, P: 875-884
Determinants of Early Alcohol Use In Healthy Adolescents: The Differential Contribution of Neuroimaging and Psychological Factors

Frauke Nees
Jelka Tzschoppe
Herta Flor
Research23 Nov 2011
Neuropsychopharmacology

Volume: 37, P: 986-995
From mechanisms to markers: novel noninvasive EEG proxy markers of the neural excitation and inhibition system in humans

Jumana Ahmad
Claire Ellis
Grainne McAlonan
ReviewsOpen Access08 Nov 2022
Translational Psychiatry

Volume: 12, P: 1-12

Search

Filter By:

Search

Quick links