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Showing 1–50 of 55 results

Advanced filters: Author: Francesco Di Gennaro Clear advanced filters

The BioSUD Biobank as a genomic resource for substance use disorders in Italy

Raffaella Maria Ribatti
Luciana de Gennaro
Francesco Montinaro
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-12
Potential role of avibactam in restoring susceptibility in Escherichia coli with two copies of bla_KPC-3 and PBP3 mutations

Simone Giuliano
Valeria Fox
Carlo Tascini
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-7
Real life experience on the use of Remdesivir in patients admitted to COVID-19 in two referral Italian hospital: a propensity score matched analysis

Nicola Veronese
Francesco Di Gennaro
Annalisa Saracino
ResearchOpen Access23 Apr 2024
Scientific Reports

Volume: 14, P: 1-7
Neonicotinoid Clothianidin reduces honey bee immune response and contributes to Varroa mite proliferation

Pesticides could increase bees’ susceptibility to parasites, but the nature of this interaction has been unclear. Here the authors show that the pesticide Clothianidin reduces the wound healing immune response in bees, allowing the ectoparasitic Varroa mites to consume more bee hemolymph and amplify reproduction.

Desiderato Annoscia
Gennaro Di Prisco
Francesco Pennacchio
ResearchOpen Access18 Nov 2020
Nature Communications

Volume: 11, P: 1-7
Incidence and burden of long COVID in Africa: a systematic review and meta-analysis

Luisa Frallonardo
Francesco Vladimiro Segala
Francesco Di Gennaro
ResearchOpen Access06 Dec 2023
Scientific Reports

Volume: 13, P: 1-8
Molecular and clinical examination of an Italian DEFECT 11 family

Wim Wuyts
Giancarlo Di Gennaro
Carlo Casali
Research22 Jun 1999
European Journal of Human Genetics

Volume: 7, P: 579-584
A 2D chiral microcavity based on apparent circular dichroism

Here the authors induce asymmetric transmission in planar Fabry–Pérot microcavities by embedding organic thin films exhibiting apparent circular dichroism (ACD), an optical phenomenon based on 2D chirality.

Tzu-Ling Chen
Andrew Salij
Randall H. Goldsmith
ResearchOpen Access09 Apr 2024
Nature Communications

Volume: 15, P: 1-11
Publisher Correction: 6-Bromoindirubin-3′-oxime intercepts GSK3 signaling to promote and enhance skeletal muscle differentiation affecting miR-206 expression in mice

Elvira Ragozzino
Mariarita Brancaccio
Francesca Varrone
Amendments and CorrectionsOpen Access19 Jun 2020
Scientific Reports

Volume: 10, P: 1
Anemia as a risk factor for disease progression in patients admitted for COVID-19: data from a large, multicenter cohort study

Nicola Veronese
Francesco Vladimiro Segala
Annalisa Saracino
ResearchOpen Access03 Jun 2023
Scientific Reports

Volume: 13, P: 1-7
SAMMY-seq reveals early alteration of heterochromatin and deregulation of bivalent genes in Hutchinson-Gilford Progeria Syndrome

Hutchinson-Gilford progeria syndrome is a genetic disease where an aberrant form of Lamin A disrupts chromatin by interfering with lamina associated domains. Here, the authors present the SAMMY-seq, a method for genome-wide characterization of heterochromatin dynamics and detect early stage alterations of heterochromatin structure in progeria primary fibroblasts, accompained by Polycomb dysfunctions.

Endre Sebestyén
Fabrizia Marullo
Chiara Lanzuolo
ResearchOpen Access08 Dec 2020
Nature Communications

Volume: 11, P: 1-16
Features of patients referring to the outpatient office due to benign prostatic hyperplasia: analysis of a national prospective cohort of 5815 cases

Paola Irene Ornaghi
Angelo Porreca
Alessandro Antonelli
Research22 Jul 2022
Prostate Cancer and Prostatic Diseases

Volume: 26, P: 730-735
MLL4-associated condensates counterbalance Polycomb-mediated nuclear mechanical stress in Kabuki syndrome

MLL4 (KMT2D) loss of function, as found in Kabuki syndrome, affects the chromatin compartmentalization of Polycomb proteins and changes the nuclear architecture. Inhibition of ATR reestablishes mechanosignaling of mutant mesenchymal stem cells and their commitment to becoming chondrocytes.

Alessandra Fasciani
Sarah D’Annunzio
Alessio Zippo
Research09 Nov 2020
Nature Genetics

Volume: 52, P: 1397-1411
A deep learning approach for facility patient attendance prediction based on medical booking data

Francesco Piccialli
Salvatore Cuomo
Gang Mei
ResearchOpen Access03 Sept 2020
Scientific Reports

Volume: 10, P: 1-11
A novel methodology for large-scale phylogeny partition

Phylogenetic analysis is used to identify transmission chains, but no software is available for the automated partition of large phylogenies. Prosperiet al. apply a new search algorithm to identify transmission clusters within the phylogeny of HIV-1gene sequences linking molecular and epidemiological data.

Mattia C.F. Prosperi
Massimo Ciccozzi
Andrea De Luca
Research24 May 2011
Nature Communications

Volume: 2, P: 1-10
Rapid oligomer formation of human muscle acylphosphatase induced by heparan sulfate

Heparan sulfate can promote formation of amyloid fibrils by different proteins. The early steps and kinetics of this process are now studied in detail, using a stopped-flow setup and the protein mAcP. The data and analysis reveal two steps, binding of mAcP to heparan sulfate and conversion to a misfolded state, followed by aggregation of the heparan sulfate–bound proteins.

Neda Motamedi-Shad
Tommaso Garfagnini
Fabrizio Chiti
Research22 Apr 2012
Nature Structural & Molecular Biology

Volume: 19, P: 547-554
Preservation of the inferior mesenteric artery in laparoscopic nerve-sparing colorectal surgery for endometriosis

Marco Scioscia
Cristiano G. S. Huscher
Giovanni Pontrelli
ResearchOpen Access24 Feb 2022
Scientific Reports

Volume: 12, P: 1-7
Impact of anti-CD20 monoclonal antibodies on serologic response to BNT162b2 vaccine in B-cell Non-Hodgkin’s lymphomas

Francesco Marchesi
Fulvia Pimpinelli
Andrea Mengarelli
Research20 Sept 2021
Leukemia

Volume: 36, P: 588-590
MRI-targeted or systematic random biopsies for prostate cancer diagnosis in biopsy naïve patients: follow-up of a PRECISION trial-like retrospective cohort

Stefano Luzzago
Ottavio de Cobelli
Gennaro Musi
Research28 Sept 2020
Prostate Cancer and Prostatic Diseases

Volume: 24, P: 406-413
Clinical and echocardiographic benefit of Sacubitril/Valsartan in a real-world population with HF with reduced ejection fraction

Maria Vincenza Polito
Angelo Silverio
Michele Ciccarelli
ResearchOpen Access20 Apr 2020
Scientific Reports

Volume: 10, P: 1-10
Confirmatory multiparametric magnetic resonance imaging at recruitment confers prolonged stay in active surveillance and decreases the rate of upgrading at follow-up

Stefano Luzzago
Michele Catellani
Ottavio de Cobelli
Research27 Jun 2019
Prostate Cancer and Prostatic Diseases

Volume: 23, P: 94-101
Infections by carbapenem-resistant Klebsiella pneumoniae in SCT recipients: a nationwide retrospective survey from Italy

C Girmenia
G M Rossolini
Giuseppe Milone
Research13 Oct 2014
Bone Marrow Transplantation

Volume: 50, P: 282-288
Characterization of shared neoantigens landscape in Mismatch Repair Deficient Endometrial Cancer

Elisa De Paolis
Camilla Nero
Francesco Fanfani
ResearchOpen Access20 Dec 2024
npj Precision Oncology

Volume: 8, P: 1-9
The neonicotinoid insecticide Clothianidin adversely affects immune signaling in a human cell line

Gennaro Di Prisco
Marco Iannaccone
Rosanna Capparelli
ResearchOpen Access18 Oct 2017
Scientific Reports

Volume: 7, P: 1-8
Ex.50.T aptamer impairs tumor–stroma cross-talk in breast cancer by targeting gremlin-1

Cristina Quintavalle
Francesco Ingenito
Gerolama Condorelli
ResearchOpen Access11 Mar 2025
Cell Death Discovery

Volume: 11, P: 1-16
Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency

Stem cell plasticity is crucial for early embryo development and the differentiation of stem cells. Here, the authors show that the extracellular protein Cripto sustains mouse ESC self-renewal and maintains mouse EpiSC as well as human ESC pluripotency and controls the metabolic reprogramming in ESCs to EpiSC transition.

Alessandro Fiorenzano
Emilia Pascale
Gabriella Minchiotti
ResearchOpen Access02 Sept 2016
Nature Communications

Volume: 7, P: 1-16
RagD auto-activating mutations impair MiT/TFE activity in kidney tubulopathy and cardiomyopathy syndrome

Mutations in the RRAGD gene are causative of an autosomal dominant disorder characterized by kidney tubulopathy and cardiomyopathy. Here, the authors identify a new RRAGD P88L mutation, demonstrating that all the identified RRAGD mutations inhibit the nuclear translocation of MiT/TFE transcription factors, resulting in defective responses to lysosomal or mitochondrial damage.

Irene Sambri
Marco Ferniani
Andrea Ballabio
ResearchOpen Access15 May 2023
Nature Communications

Volume: 14, P: 1-13
Comparative one-month safety and effectiveness of five leading new-generation devices for transcatheter aortic valve implantation

Arturo Giordano
Nicola Corcione
Fabrizio Tomai
ResearchOpen Access19 Nov 2019
Scientific Reports

Volume: 9, P: 1-12
Monocyte-macrophage membrane expression of IL-1R2 is a severity biomarker in sepsis

Domenico Supino
Sadaf Davoudian
Cecilia Garlanda
ResearchOpen Access10 Apr 2025
Cell Death & Disease

Volume: 16, P: 1-11
KRAS-regulated glutamine metabolism requires UCP2-mediated aspartate transport to support pancreatic cancer growth

UCP2 is shown in yeast and mammalian cells to transport aspartate out of mitochondria, thus enabling KRAS-mutated pancreatic ductal adenocarcinoma cells to perform glutaminolysis to support cancer growth.

Susanna Raho
Loredana Capobianco
Giuseppe Fiermonte
Research23 Nov 2020
Nature Metabolism

Volume: 2, P: 1373-1381
Magnetic resonance-conditional cardiac implantable electronic devices: an Italian perspective on the prevalence of mixed-brand systems over time

Davide Saporito
Eduardo Celentano
Massimo Giammaria
ResearchOpen Access06 Nov 2024
Scientific Reports

Volume: 14, P: 1-10
Fast magnetic field amplification in distant galaxy clusters

LOFAR reveals diffuse radio emission in massive high-redshift clusters, whose high radio luminosities indicate magnetic field strengths similar to those in nearby clusters, suggesting fast magnetic field amplification in the early Universe.

Gabriella Di Gennaro
Reinout J. van Weeren
Aurora Simionescu
Research02 Nov 2020
Nature Astronomy

Volume: 5, P: 268-275
Clinical characteristics and molecular aspects of low-grade serous ovarian and peritoneal cancer: a multicenter, observational, retrospective analysis of MITO Group (MITO 22)

Lucia Musacchio
Daniela Califano
Sandro Pignata
Research22 Jul 2022
British Journal of Cancer

Volume: 127, P: 1479-1486
Correction: Confirmatory multiparametric magnetic resonance imaging at recruitment confers prolonged stay in active surveillance and decreases the rate of upgrading at follow-up

Stefano Luzzago
Michele Catellani
Ottavio de Cobelli
Amendments and Corrections13 Dec 2019
Prostate Cancer and Prostatic Diseases

Volume: 23, P: 195
Paper-based electrochemical device for early detection of integrin αvβ6 expressing tumors

The detection of cancer in its early stages can greatly prevent disease development, however, current technologies for tumor detection present several limitations. Here, the authors develop a paper-based electrochemical device for detecting cancer-derived small extracellular vesicles (S-EVs) in fluids, recognizing αvβ6-containing S-EVs down to a limit of 0.7*10³ S-EVs/mL with a linear range up to 10⁵ S-EVs/mL.

Stefano Cinti
Stefano Tomassi
Luciana Marinelli
ResearchOpen Access21 Mar 2024
Communications Chemistry

Volume: 7, P: 1-9
Colorectal cancer after bariatric surgery (Cric-Abs 2020): Sicob (Italian society of obesity surgery) endorsed national survey

Maria Chiara Ciccioriccio
Angelo Iossa
Marco Antonio Zappa
Research19 Jul 2021
International Journal of Obesity

Volume: 45, P: 2527-2531
Central obesity, body mass index, metabolic syndrome and mortality in Mediterranean breast cancer patients

Anna Crispo
Livia S. A. Augustin
Grazia Arpino
ResearchOpen Access01 Dec 2023
Scientific Reports

Volume: 13, P: 1-11
The prognostic relevance of HER2-positivity gain in metastatic breast cancer in the ChangeHER trial

Laura Pizzuti
Maddalena Barba
Patrizia Vici
ResearchOpen Access02 Jul 2021
Scientific Reports

Volume: 11, P: 1-10
Hsp60 response in experimental and human temporal lobe epilepsy

Antonella Marino Gammazza
Roberto Colangeli
Alberto J. L. Macario
ResearchOpen Access24 Mar 2015
Scientific Reports

Volume: 5, P: 1-8
A machine-learning parsimonious multivariable predictive model of mortality risk in patients with Covid-19

Rita Murri
Jacopo Lenkowicz
Lorenzo Zileri Dal Verme
ResearchOpen Access27 Oct 2021
Scientific Reports

Volume: 11, P: 1-10
Extended coagulation profile of children with Long Covid: a prospective study

Leonardo Di Gennaro
Piero Valentini
Danilo Buonsenso
ResearchOpen Access01 Nov 2022
Scientific Reports

Volume: 12, P: 1-10
Reduced SIRT1 and SIRT2 expression promotes adipogenesis of human visceral adipose stem cells and associates with accumulation of visceral fat in human obesity

Sebastio Perrini
Stefania Porro
Francesco Giorgino
Research28 Aug 2019
International Journal of Obesity

Volume: 44, P: 307-319
Effects of different pioneer and exotic species on the changes of degraded soils

Claudio Cacace
Juan C. García-Gil
Andreina Traversa
ResearchOpen Access03 Nov 2022
Scientific Reports

Volume: 12, P: 1-9
Unveiling the mechanistic link between extracellular amyloid fibrils, mechano-signaling and YAP activation in cancer

Francesco Farris
Alice Elhagh
Angela Bachi
ResearchOpen Access11 Jan 2024
Cell Death & Disease

Volume: 15, P: 1-13
Impact of SPRINT results on hypertension guidelines: implications for “frail” elderly patients

Gennaro Russo
Ilaria Liguori
Pasquale Abete
Reviews10 Jul 2018
Journal of Human Hypertension

Volume: 32, P: 633-638
PTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells is mediated by p27^kip1

Paola Bruni
Angelo Boccia
Giuseppe Viglietto
Research05 Jul 2000
Oncogene

Volume: 19, P: 3146-3155
Efficacy and safety of human papillomavirus vaccination in HIV-infected patients: a systematic review and meta-analysis

Antonella Zizza
Federico Banchelli
Roberto D’Amico
ResearchOpen Access02 Mar 2021
Scientific Reports

Volume: 11, P: 1-13
HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome

Simona di Martino
Carla Azzurra Amoreo
Mario Cioce
Research09 Jan 2018
Oncogene

Volume: 37, P: 1369-1385
6-Bromoindirubin-3′-oxime intercepts GSK3 signaling to promote and enhance skeletal muscle differentiation affecting miR-206 expression in mice

Elvira Ragozzino
Mariarita Brancaccio
Francesca Varrone
ResearchOpen Access02 Dec 2019
Scientific Reports

Volume: 9, P: 1-17
Apoptotic cell death in disease—Current understanding of the NCCD 2023

Ilio Vitale
Federico Pietrocola
Lorenzo Galluzzi
Reviews26 Apr 2023
Cell Death & Differentiation

Volume: 30, P: 1097-1154
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43

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