As immune checkpoint therapy is more frequently used for cancer, side effects such as Stevens-Johson syndrome / toxic epidermal necrolysis (SJS/TEN) are becoming more common. Here the authors use single cell transcriptomics to implicate TNF and CXCL10 in recruitment of CXCR3+ cytotoxic T cell in SJS/TEN skin lesions.
- Chun-Bing Chen
- Shuen-Iu Hung
- Wen-Hung Chung
