Nature Search

SH2 ___domain specificity and activity modified by a single residue

Luc E. M. Marengere
Zhou Songyang
Tony Pawson
Research09 Jun 1994
Nature

Volume: 369, P: 502-505
Epileptic seizures caused by inactivation of a novel gene, jerky, related to centromere binding protein–B in transgenic mice

Miklos Toth
Joseph Grimsby
Gerald P. Donovan
Research01 Sept 1995
Nature Genetics

Volume: 11, P: 71-75
Direct demonstration of an intramolecular SH2—phosphotyrosine interaction in the Crk protein

Michael K. Rosen
Toshio Yamazaki
Lewis E. Kay
Research30 Mar 1995
Nature

Volume: 374, P: 477-479
Transgenic RNA interference in ES cell–derived embryos recapitulates a genetic null phenotype

Tilo Kunath
Gerald Gish
Janet Rossant
Research07 Apr 2003
Nature Biotechnology

Volume: 21, P: 559-561
RET alternate splicing influences the interaction of activated RET with the SH2 and PTB domains of Shc, and the SH2 ___domain of Grb2

María Jesús Lorenzo
Gerald D Gish
Darrin P Smith
Research20 Feb 1997
Oncogene

Volume: 14, P: 763-771
SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal ___domain control termination

Symmetric dimethylation of the human RNA polymerase II C-terminal ___domain residue R1810 by the protein arginine methyltransferase 5 (PRMT5) directly recruits the protein survival of motor neuron (SMN) and indirectly recruits the helicase senataxin to resolve R-loops and promote transcription termination.

Dorothy Yanling Zhao
Gerald Gish
Jack F. Greenblatt
Research23 Dec 2015
Nature

Volume: 529, P: 48-53
Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells

Samantha Gruenheid
Rebekah DeVinney
B. Brett Finlay
Research16 Aug 2001
Nature Cell Biology

Volume: 3, P: 856-859
Protein context shapes the specificity of SH3 ___domain-mediated interactions in vivo

The SRC Homology 3 (SH3) domains mediate protein–protein interactions (PPIs). Here, the authors assess the SH3-mediated PPIs in yeast, and show that the identity of the protein itself and the position of the SH3 both affect the interaction specificity and thus the PPI-dependent cellular functions.

Ugo Dionne
Émilie Bourgault
Christian R. Landry
ResearchOpen Access12 Mar 2021
Nature Communications

Volume: 12, P: 1-15
PTEN regulates cilia through Dishevelled

The formation of motile cilia is regulated by Dishevelled (DVL), a central component in WNT signalling and planar cell polarity (PCP). Here the authors identify DVL as a novel substrate of the phosphatase PTEN, coupling PTEN to cilia dynamics and PCP.

Iryna Shnitsar
Mikhail Bashkurov
Miriam Barrios-Rodiles
ResearchOpen Access24 Sept 2015
Nature Communications

Volume: 6, P: 1-14
Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product

Sylvain Latour
Gerald Gish
André Veillette
Research01 Aug 2001
Nature Immunology

Volume: 2, P: 681-690
Kinetic pathway for interfacial electron transfer from a semiconductor to a molecule

While important for solar energy conversion, it is unclear whether electron transfer at molecular–semiconductor interfaces is influenced only by the distance over which the injected electron tunnels and whether specific through-bond pathways are active. Now, a pathway for electron transfer has been identified through comparative analysis of compounds with phenyl- or xylyl-thiophene bridges.

Ke Hu
Amber D. Blair
Curtis P. Berlinguette
Research20 Jun 2016
Nature Chemistry

Volume: 8, P: 853-859
Initial sequencing and analysis of the human genome

Eric S. Lander
Lauren M. Linton
Michael J. Morgan
articles01 Feb 2001
Nature

Volume: 409, P: 860-921
The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture

Robert J Ingham
Gerald Gish
Tony Pawson
Reviews15 Mar 2004
Oncogene

Volume: 23, P: 1972-1984

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SH2 ___domain specificity and activity modified by a single residue

Epileptic seizures caused by inactivation of a novel gene, jerky, related to centromere binding protein–B in transgenic mice

Direct demonstration of an intramolecular SH2—phosphotyrosine interaction in the Crk protein

Transgenic RNA interference in ES cell–derived embryos recapitulates a genetic null phenotype

RET alternate splicing influences the interaction of activated RET with the SH2 and PTB domains of Shc, and the SH2 ___domain of Grb2

SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal ___domain control termination

Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells

Protein context shapes the specificity of SH3 ___domain-mediated interactions in vivo

PTEN regulates cilia through Dishevelled

Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product

Kinetic pathway for interfacial electron transfer from a semiconductor to a molecule

Initial sequencing and analysis of the human genome

The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture

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