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Lan et al. demonstrate the high performance of plasma p-tau217 in detecting and tracking multiple aspects of Alzheimer’s disease pathology, outperforming other plasma tau biomarkers across two Chinese cohorts (GHABS and Huashan) and the North American ADNI cohort.

Recycling of commodity plastics remains challenging due to the presence of additives and mixed waste streams. Here the authors develop a strategy for co-upcycling polycarbonate, and polyethylene terephthalate, two types of waste commodity polymers, into polyarylate, a high-performance transparent engineering plastic.

Transition-metal-catalyzed asymmetric multicomponent reactions with two similar substrates often suffer from the lack of strategies to control the chemo-, regio-, and stereoselectivity. Here, the authors report a Cu(I)-catalyzed asymmetric radical 1,2-carboalkynylation of two different terminal alkynes and alkyl halides with chemo-, regio-, and stereoselectivity.

The irradiation of crystalline materials is known to create various types of lattice defects, which can degrade mechanical performance. Here, Xu et al. observe the in-situnucleation and growth of atomic-scale voids in magnesium during electron irradiation.

Topological boundary modes within charge-ordered states have not yet been observed experimentally. Now an in-gap boundary mode, stemming solely from the charge order, is visualized in the topological material Ta₂Se₈I.

Quantum simulations of topological matter with superconducting qubits have been attracting attention recently. Xiang et al. realize 2D and bilayer Chern insulators with synthetic dimensions on a programmable 30-qubit-ladder superconducting processor, showing bulk-boundary correspondence.

Scanning tunnelling microscopy is used to reveal a new topological kagome magnet with an intrinsic Chern quantum phase, which shows a distinct Landau fan structure with a large Chern gap.

A universal and non-destructive technique is developed to process diverse types of powder into micro- or nanofibres, providing flexibility for material design and applications based on functional particles.

Topologically protected hinge modes could be important for developing quantum devices, but electronic transport through those states has not been demonstrated. Now quantum transport has been shown in gapless topological hinge states.

The advancement of high entropy alloy development is both rapid and challenging. Here, the authors discover an unusual Sabatier principle operating on the high entropy alloy surface, which leads to a notable enhancement in catalytic activity for hydrogen evolution reactions.

Defective platinum diselenide can serve as a highly efficient and stable catalyst for the oxygen reduction reaction outperforming commercial Pt/C catalysts, which is achieved by a restructuring approach via electrochemical cycling.

Quantum devices offer the potential to simulate quantum phenomena, which are otherwise computationally intractable. Here, Shi, Sun, Wang and coauthors use a superconducting quantum simulator to study spin-transport at infinite temperature.

A study combining spectroscopy and mathematical topology  reports the observation of linked node loops in a quantum magnet, with properties suggesting a Seifert bulk–boundary correspondence.

Frustrated kagome magnets host both fermionic and bosonic excitations, but evidence of their interplay has been elusive. Here, the authors report a pronounced renormalization of electron bands near the Fermi surface due to the coupling with a flat phonon band in a kagome paramagnet, CoSn.

The effect of hydrogen embrittlement on metal nanostructures is still unclear. Here, the authors combine nanomechanical testing and molecular dynamics simulations to show that hydrogen can suppress surface dislocation nucleation in silver nanowires.

The Gabija system is a newly discovered bacterial immune system. Here, the authors report the EM structure of the Gabija complex at 3.6 Å. Here, the authors show that when invading phages depletes cellular NTP and dNTP, the nuclease activity of Gabija complex is activated and cleaves the circular DNA to prevent phage DNA replication.

Authors control heat transfer through twisting moiré conductive thermal metasurface, showcasing the potential for manipulating thermal conductivity and temperature gradients with imitated magic angles, thereby realizing multifunctional thermal metadevices.

Crystalline nanowires with point defects show large anelastic behaviour, leading to efficient mechanical energy dissipation.

Weyl semimetals exhibit a rich variety of transport phenomena, but it usually takes low temperatures and a strong magnetic field to realize them. Here, Quirk et al. show that when the ferromagnetic Weyl semimetal Co₂MnGa is polished to micron thicknesses, it develops a remarkable resistance anisotropy that has opposite directions on opposing crystal faces. They show that this unusual transport property, which is robust at room temperature and in a strong magnetic field, may be generated by distinct conducting states on the surfaces of these thin crystals.

The unexpected phenomenon of rapid, long-distance transport of an ultrathin and uniform metal film on two-dimensional crystals is reported at temperatures well below the melting points of all of the materials involved. The effect is generalizable and may offer possibilities in confined space chemistry, as well as in two-dimensional crystal growth and devices.

Lithium mining is both energy and land intensive. The use of a 3D porous natural cellulose fibre structure enables an interfacial crystallization method for the selective extraction of lithium from both brine and seawater that can be a significant alternative to mining.

Quantum computers based on superconducting transmon qubits are limited by single qubit lifetimes and coherence times, which are orders of magnitude shorter than limits imposed by bulk material properties. Here, the authors fabricate two-dimensional transmon qubits with both lifetimes and coherence times longer than 0.3 milliseconds by replacing niobium with tantalum in the device.

We show that an insulating bulk state and helical edge state coexist in Bi₄Br₄ and that this coexistence persists up to room temperature.

1D nanostructures are widely regarded as important building blocks for a broad range of applications. Here, the authors study dislocation-mediated plastic deformation in penta-twinned silver nanowires, finding that in situdeformation at small to moderate strains can be entirely reversible.

A micrometeorite collected at the top of Monte Gariglione, Italy, contains intermetallic (Al,Cu)-alloys including a natural quasicrystal approximant phase, according to mineralogical investigations using scanning and transmission electron microscopy.

Whether and how fish might benefit from swimming in schools is an ongoing intriguing debate. Li et al. conduct experiments with biomimetic robots and also with real fish to reveal a new behavioural strategy by which followers can exploit the vortices shed by a near neighbour.

Yue, Zong, Li, Li, Zhang, Wu et al. introduce an in toto live-imaging system to track cardiac ventricle chamber formation at single-cell resolution for up to 1.5 days and digitally reconstruct cell dynamics.

We develop a wearable and interactive multicolored photochromic fiber using the thermal drawing technique, which overcomes the dependence on external light sources and the non-uniform light emission observed in polymer optical and photochromic fibers.