Nature Search

A new class of synthetic antibacterials acting on lipopolysaccharide biosynthesis

Stephen M. Hammond
Alf Claesson
Bertil Ekström
Research25 Jun 1987
Nature

Volume: 327, P: 730-732
Ancient Plasmodium genomes shed light on the history of human malaria

Genomic analysis of Plasmodium DNA from 36 ancient individuals provides insight into the global distribution and spread of malaria-causing species during around 5,500 years of human history.

Megan Michel
Eirini Skourtanioti
Johannes Krause
ResearchOpen Access12 Jun 2024
Nature

Volume: 631, P: 125-133
Early contact between late farming and pastoralist societies in southeastern Europe

Archaeogenetic analysis of 135 individuals from the zone between southeastern Europe and the northwestern Black Sea region indicates contacts between farming and pastoralist populations at the end of the Copper Age.

Sandra Penske
Adam B. Rohrlach
Wolfgang Haak
ResearchOpen Access19 Jul 2023
Nature

Volume: 620, P: 358-365
Ancient genomes reveal social and genetic structure of Late Neolithic Switzerland

European populations underwent strong genetic changes during the Neolithic. Here, Furtwängler et al. provide ancient nuclear and mitochondrial genomic data from the region of Switzerland during the end of the Neolithic and the Early Bronze Age that reveal a complex genetic turnover during the arrival of steppe ancestry.

Anja Furtwängler
A. B. Rohrlach
Johannes Krause
ResearchOpen Access20 Apr 2020
Nature Communications

Volume: 11, P: 1-11
Ancient DNA reveals admixture history and endogamy in the prehistoric Aegean

The authors generate a genome-wide dataset of 102 individuals who lived in Crete, the Greek mainland and the Aegean islands between the Neolithic and the Iron Age, identifying high levels of biological and cultural connectedness within the ancient Aegean.

Eirini Skourtanioti
Harald Ringbauer
Philipp W. Stockhammer
ResearchOpen Access16 Jan 2023
Nature Ecology & Evolution

Volume: 7, P: 290-303
Synergism between IL7R and CXCR4 drives BCR-ABL induced transformation in Philadelphia chromosome-positive acute lymphoblastic leukemia

Emergence of ABL1 kinase inhibitor resistant clones may cause disease relapse in Philadelphia chromosome-positive acute lymphoblastic leukemia. Here, the authors show interleukin 7 receptor (IL7R) signaling to contribute to this resistance mechanism, and that targeting the IL7R pathway may suppress incurable drug-resistant leukemia forms.

Hend Abdelrasoul
Anila Vadakumchery
Hassan Jumaa
ResearchOpen Access24 Jun 2020
Nature Communications

Volume: 11, P: 1-12
Phylogeography of the second plague pandemic revealed through analysis of historical Yersinia pestis genomes

The second plague pandemic, caused by Yersinia pestis, started in the 14th century and recurred in Europe until the 18th century. Here, the authors reconstruct ancient Y. pestis genomes from human remains spanning this period, shedding light into the phylogeography and population structure of the European strains.

Maria A. Spyrou
Marcel Keller
Johannes Krause
ResearchOpen Access02 Oct 2019
Nature Communications

Volume: 10, P: 1-13
Emergence of human-adapted Salmonella enterica is linked to the Neolithization process

Ancient Salmonella enterica genomes from Neolithic Eurasian humans compared with those from later archaeological contexts illuminate the evolving host specificity of the pathogen from an initial multi-mammalian adaptation towards an increasingly human specialization.

Felix M. Key
Cosimo Posth
Johannes Krause
Research24 Feb 2020
Nature Ecology & Evolution

Volume: 4, P: 324-333
Author Correction: Ancient genomes reveal social and genetic structure of Late Neolithic Switzerland

Anja Furtwängler
A. B. Rohrlach
Johannes Krause
Amendments and CorrectionsOpen Access16 Sept 2020
Nature Communications

Volume: 11, P: 1-2
BCL11A intellectual developmental disorder: defining the clinical spectrum and genotype-phenotype correlations

Angela Peron
Felice D’Arco
Cristina Dias
ResearchOpen Access24 Oct 2024
European Journal of Human Genetics

Volume: 33, P: 312-324
Eruca sativa seed napin structural insights and thorough functional characterization

Binish Khaliq
Sven Falke
Ahmed Akrem
ResearchOpen Access15 Dec 2021
Scientific Reports

Volume: 11, P: 1-13
Using Y-chromosome capture enrichment to resolve haplogroup H2 shows new evidence for a two-path Neolithic expansion to Western Europe

Adam B. Rohrlach
Luka Papac
Wolfgang Haak
ResearchOpen Access22 Jul 2021
Scientific Reports

Volume: 11, P: 1-11
Ratio of mitochondrial to nuclear DNA affects contamination estimates in ancient DNA analysis

Anja Furtwängler
Ella Reiter
Johannes Krause
ResearchOpen Access19 Sept 2018
Scientific Reports

Volume: 8, P: 1-8
CD79a promotes CNS-infiltration and leukemia engraftment in pediatric B-cell precursor acute lymphoblastic leukemia

Lenk et al find that the preB cell receptor (preBCR) is associated with infiltration and relapse of acute lymphoblastic leukemia in the central nervous system (CNS). They also show that downregulation of preBCR component CD79a reduces the engraftment of leukemia cells in different murine xenograft models, particularly in the CNS.

Lennart Lenk
Michela Carlet
Denis M. Schewe
ResearchOpen Access15 Jan 2021
Communications Biology

Volume: 4, P: 1-6

Search

A new class of synthetic antibacterials acting on lipopolysaccharide biosynthesis

Ancient Plasmodium genomes shed light on the history of human malaria

Early contact between late farming and pastoralist societies in southeastern Europe

Ancient genomes reveal social and genetic structure of Late Neolithic Switzerland

Ancient DNA reveals admixture history and endogamy in the prehistoric Aegean

Synergism between IL7R and CXCR4 drives BCR-ABL induced transformation in Philadelphia chromosome-positive acute lymphoblastic leukemia

Phylogeography of the second plague pandemic revealed through analysis of historical Yersinia pestis genomes

Emergence of human-adapted Salmonella enterica is linked to the Neolithization process

Author Correction: Ancient genomes reveal social and genetic structure of Late Neolithic Switzerland

BCL11A intellectual developmental disorder: defining the clinical spectrum and genotype-phenotype correlations

Eruca sativa seed napin structural insights and thorough functional characterization

Using Y-chromosome capture enrichment to resolve haplogroup H2 shows new evidence for a two-path Neolithic expansion to Western Europe

Ratio of mitochondrial to nuclear DNA affects contamination estimates in ancient DNA analysis

CD79a promotes CNS-infiltration and leukemia engraftment in pediatric B-cell precursor acute lymphoblastic leukemia

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