Nature Search

Substrate entering and product leaving trajectories predict an engulfing dynamic for the major conformational change of the &946;-lactam acylase

Xi Huang
Jun Yin
Guo-Ping Zhao
ResearchOpen Access15 Nov 2008
Nature Precedings

P: 1
Identification and classification of all potential hemolysin encoding genes and their products from Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai

Yi-xuan Zhang
Yan Geng
Guo-ping Zhao
Research01 Apr 2005
Acta Pharmacologica Sinica

Volume: 26, P: 453-461
PPAR-γ2 and PTPRD gene polymorphisms influence type 2 diabetes patients' response to pioglitazone in China

Qi Pei
Qiong Huang
Zhao-qian Liu
Research12 Nov 2012
Acta Pharmacologica Sinica

Volume: 34, P: 255-261
Synergistic effect of combining paeonol and cisplatin on apoptotic induction of human hepatoma cell lines

Shu-ping Xu
Guo-ping Sun
Wei Wei
Research01 Jun 2007
Acta Pharmacologica Sinica

Volume: 28, P: 869-878
Mapping ticks and tick-borne pathogens in China

Ticks are an important vector of disease in China, posing threats to humans, livestock and wild animals. Here, Zhao et al. compile a database of the distributions of the 124 tick species known in China and 103 tick-borne pathogens and predict the additional suitable habitats for the predominant vector species.

Guo-Ping Zhao
Yi-Xing Wang
Li-Qun Fang
ResearchOpen Access17 Feb 2021
Nature Communications

Volume: 12, P: 1-13
Cellular differentiation into hyphae and spores in halophilic archaea

Bacteria of the genus Streptomyces have complex life cycles involving cellular differentiation and multicellular structures that have never been observed in archaea. Here, the authors show that several halophilic archaea display a life cycle resembling that of Streptomyces bacteria, undergoing cellular differentiation into mycelia and spores.

Shu-Kun Tang
Xiao-Yang Zhi
Ping Xu
ResearchOpen Access01 Apr 2023
Nature Communications

Volume: 14, P: 1-14
Creating a bacterium that forms eukaryotic nucleosome core particles

The nucleosome is one of the hallmarks of eukaryotes, a dynamic platform that supports many critical functions in eukaryotic cells. Here, the authors engineer the in vivo assembly of the nucleosome core in E. coli, forming nucleosome arrays that have profiles resembling those in eukaryotic cells, and are viable to have sustained growth under a condition for moderate histones expression.

Xinyun Jing
Niubing Zhang
Xuan Li
ResearchOpen Access27 Sept 2024
Nature Communications

Volume: 15, P: 1-16
Phase separation modulates the assembly and dynamics of a polarity-related scaffold-signaling hub

The polarization of distinct scaffold-signaling hubs at opposite cell poles constitutes the basis of asymmetric cell division. Here, the authors show that phase separation serves as a general mechanism to regulate the assembly and dynamics of a new-pole scaffold-signaling hub.

Wei Tan
Sihua Cheng
Wei Zhao
ResearchOpen Access23 Nov 2022
Nature Communications

Volume: 13, P: 1-14
A recombinant BCG with surface-displayed antigen induces humoral and cellular immune responses

Jin-Yu Zhang
Zhi-Dong Hu
Liang-Dong Lyu
ResearchOpen Access16 May 2025
Scientific Reports

Volume: 15, P: 1-15
Addendum: Cellular differentiation into hyphae and spores in halophilic archaea

Shu-Kun Tang
Xiao-Yang Zhi
Ping Xu
Amendments and CorrectionsOpen Access01 Feb 2024
Nature Communications

Volume: 15, P: 1
The cyanobacterial ornithine–ammonia cycle involves an arginine dihydrolase

An ornithine–ammonia cycle involving an arginine dihydrolase was identified in cyanobacteria. This cycle serves as a conduit in the nitrogen storage-and-remobilization machinery and enables cellular adaptation to nitrogen fluctuations.

Hao Zhang
Yujie Liu
Chen Yang
Research09 Apr 2018
Nature Chemical Biology

Volume: 14, P: 575-581
Impact of ginsenoside Rb1 on gut microbiome and associated changes in pharmacokinetics in rats

Yue Chen
Kang-xi Zhang
Guo-ping Zhao
ResearchOpen Access10 Sept 2024
Scientific Reports

Volume: 14, P: 1-12
Experimental and Theoretical Demonstrations for the Mechanism behind Enhanced Microbial Electron Transfer by CNT Network

Xian-Wei Liu
Jie-Jie Chen
Han-Qing Yu
ResearchOpen Access16 Jan 2014
Scientific Reports

Volume: 4, P: 1-7
Phenothiazine Derivative-Accelerated Microbial Extracellular Electron Transfer in Bioelectrochemical System

Xian-Wei Liu
Xue-Fei Sun
Han-Qing Yu
ResearchOpen Access08 Apr 2013
Scientific Reports

Volume: 3, P: 1-7
Costunolide normalizes neuroinflammation and improves neurogenesis deficits in a mouse model of depression through inhibiting microglial Akt/mTOR/NF-κB pathway

Shao-qi Zhang
Qiao Deng
Dong Liu
ResearchOpen Access26 Feb 2025
Acta Pharmacologica Sinica

Volume: 46, P: 1864-1876
Molecular mechanisms underlying the cholesterol-lowering effect of Ginkgo biloba extract in hepatocytes: a comparative study with lovastatin

Zuo-quan Xie
Gai Liang
Qing-hua Zhang
Research24 Aug 2009
Acta Pharmacologica Sinica

Volume: 30, P: 1262-1275
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

Xuejun Zhang and colleagues report results of a genome-wide association study of systemic lupus erythematosus (SLE) in a Chinese Han population. Their work identifies nine new SLE susceptibility loci and reveals overlap in the spectrum of risk alleles shared between Chinese Han and European populations.

Jian-Wen Han
Hou-Feng Zheng
Xue-Jun Zhang
Research18 Oct 2009
Nature Genetics

Volume: 41, P: 1234-1237
Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2

Dai Zhang and colleagues report a genome-wide association study for schizophrenia in the Han Chinese population. They identify a new susceptibility locus at 11p11.2 and also identify a locus at 6p21-22.1 in the extended MHC region, which has previously been reported to be associated with schizophrenia in individuals of European descent.

Wei-Hua Yue
Hai-Feng Wang
Dai Zhang
Research30 Oct 2011
Nature Genetics

Volume: 43, P: 1228-1231
Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing

Shuang-Xi Ren
Gang Fu
Guo-Ping Zhao
ResearchOpen Access24 Apr 2003
Nature

Volume: 422, P: 888-893
Author Correction: CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA

Shi-Yuan Li
Qiu-Xiang Cheng
Jin Wang
Amendments and CorrectionsOpen Access23 Jan 2024
Cell Research

Volume: 34, P: 266-267
A dataset of distribution and diversity of blood-sucking mites in China

Fan-Fei Meng
Qiang Xu
Wei Liu
ResearchOpen Access05 Aug 2021
Scientific Data

Volume: 8, P: 1-7
Gossypium barbadense genome sequence provides insight into the evolution of extra-long staple fiber and specialized metabolites

Xia Liu
Bo Zhao
Xiao-Ya Chen
ResearchOpen Access30 Sept 2015
Scientific Reports

Volume: 5, P: 1-14
Author Correction: CRISPR-Cas12a-assisted nucleic acid detection

Shi-Yuan Li
Qiu-Xiang Cheng
Jin Wang
Amendments and CorrectionsOpen Access12 Mar 2019
Cell Discovery

Volume: 5, P: 1
Reversible lysine acetylation is involved in DNA replication initiation by regulating activities of initiator DnaA in Escherichia coli

Qiufen Zhang
Aiping Zhou
Yu-Feng Yao
ResearchOpen Access03 Aug 2016
Scientific Reports

Volume: 6, P: 1-13
Systematic analysis reveals molecular characteristics of ERG-negative prostate cancer

Qingyu Xiao
Yidi Sun
Hong Li
ResearchOpen Access27 Aug 2018
Scientific Reports

Volume: 8, P: 1-11
Long-term strain improvements accumulate mutations in regulatory elements responsible for hyper-production of cellulolytic enzymes

Guodong Liu
Lei Zhang
Yinbo Qu
ResearchOpen Access28 Mar 2013
Scientific Reports

Volume: 3, P: 1-7
Genomic perspectives on the evolution of fungal entomopathogenicity in Beauveria bassiana

Guohua Xiao
Sheng-Hua Ying
Ming-Guang Feng
ResearchOpen Access02 Jul 2012
Scientific Reports

Volume: 2, P: 1-10
Composition and Interactions of Hepatitis B Virus Quasispecies Defined the Virological Response During Telbivudine Therapy

Bin Zhou
Hui Dong
Jinlin Hou
ResearchOpen Access24 Nov 2015
Scientific Reports

Volume: 5, P: 1-10
Genomewide Analysis of Rat Periaqueductal Gray-Dorsal Horn Reveals Time-, Region- and Frequency-Specific mRNA Expression Changes in Response to Electroacupuncture Stimulation

Ke Wang
Xiao-Hui Xiang
Cai-Lian Cui
ResearchOpen Access27 Oct 2014
Scientific Reports

Volume: 4, P: 1-8
Characterization of a novel toxin-antitoxin module, VapBC, encoded by Leptospira interrogans chromosome

Yi Xuan ZHANG
Xiao Kui GUO
Guo Ping ZHAO
Research01 Jun 2004
Cell Research

Volume: 14, P: 208-216
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism

Wei Zhao
Yi Zhong
Guo-Ping Zhao
Research22 Jun 2010
Cell Research

Volume: 20, P: 1096-1108
CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA

Shi-Yuan Li
Qiu-Xiang Cheng
Jin Wang
CorrespondenceOpen Access12 Mar 2018
Cell Research

Volume: 28, P: 491-493
CRISPR-Cas12a-assisted nucleic acid detection

Shi-Yuan Li
Qiu-Xiang Cheng
Jin Wang
CorrespondenceOpen Access24 Apr 2018
Cell Discovery

Volume: 4, P: 1-4
High-coverage proteome analysis reveals the first insight of protein modification systems in the pathogenic spirochete Leptospira interrogans

Xing-Jun Cao
Jie Dai
Rong Zeng
Research17 Nov 2009
Cell Research

Volume: 20, P: 197-210
Comparative proteogenomic analysis of the Leptospira interrogans virulence-attenuated strain IPAV against the pathogenic strain 56601

Yi Zhong
Xiao Chang
Xiao-Kui Guo
Research22 Mar 2011
Cell Research

Volume: 21, P: 1210-1229

Search

Substrate entering and product leaving trajectories predict an engulfing dynamic for the major conformational change of the &946;-lactam acylase

Identification and classification of all potential hemolysin encoding genes and their products from Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai

PPAR-γ2 and PTPRD gene polymorphisms influence type 2 diabetes patients' response to pioglitazone in China

Synergistic effect of combining paeonol and cisplatin on apoptotic induction of human hepatoma cell lines

Mapping ticks and tick-borne pathogens in China

Cellular differentiation into hyphae and spores in halophilic archaea

Creating a bacterium that forms eukaryotic nucleosome core particles

Phase separation modulates the assembly and dynamics of a polarity-related scaffold-signaling hub

A recombinant BCG with surface-displayed antigen induces humoral and cellular immune responses

Addendum: Cellular differentiation into hyphae and spores in halophilic archaea

The cyanobacterial ornithine–ammonia cycle involves an arginine dihydrolase

Impact of ginsenoside Rb1 on gut microbiome and associated changes in pharmacokinetics in rats

Experimental and Theoretical Demonstrations for the Mechanism behind Enhanced Microbial Electron Transfer by CNT Network

Phenothiazine Derivative-Accelerated Microbial Extracellular Electron Transfer in Bioelectrochemical System

Costunolide normalizes neuroinflammation and improves neurogenesis deficits in a mouse model of depression through inhibiting microglial Akt/mTOR/NF-κB pathway

Molecular mechanisms underlying the cholesterol-lowering effect of Ginkgo biloba extract in hepatocytes: a comparative study with lovastatin

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2

Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing

Author Correction: CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA

A dataset of distribution and diversity of blood-sucking mites in China

Gossypium barbadense genome sequence provides insight into the evolution of extra-long staple fiber and specialized metabolites

Author Correction: CRISPR-Cas12a-assisted nucleic acid detection

Reversible lysine acetylation is involved in DNA replication initiation by regulating activities of initiator DnaA in Escherichia coli

Systematic analysis reveals molecular characteristics of ERG-negative prostate cancer

Long-term strain improvements accumulate mutations in regulatory elements responsible for hyper-production of cellulolytic enzymes

Genomic perspectives on the evolution of fungal entomopathogenicity in Beauveria bassiana

Composition and Interactions of Hepatitis B Virus Quasispecies Defined the Virological Response During Telbivudine Therapy

Genomewide Analysis of Rat Periaqueductal Gray-Dorsal Horn Reveals Time-, Region- and Frequency-Specific mRNA Expression Changes in Response to Electroacupuncture Stimulation

Characterization of a novel toxin-antitoxin module, VapBC, encoded by Leptospira interrogans chromosome

Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism

CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA

CRISPR-Cas12a-assisted nucleic acid detection

High-coverage proteome analysis reveals the first insight of protein modification systems in the pathogenic spirochete Leptospira interrogans

Comparative proteogenomic analysis of the Leptospira interrogans virulence-attenuated strain IPAV against the pathogenic strain 56601

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