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Showing 1–50 of 59 results

Advanced filters: Author: Hailing Zhang Clear advanced filters

Dysregulations of C1QA, C1QB, C1QC and C5AR1 as candidate biomarkers of vascular dementia

Yawen Xu
Hailing Zhang
Xiaoying Bi
ResearchOpen Access25 May 2025
npj Aging

Volume: 11, P: 1-10
Phonon dispersion of buckled two-dimensional GaN

The authors investigate phonon behaviors of buckled two-dimensional GaN, determining the phonon dispersion of buckled two-dimensional GaN, revealing a larger phonon band gap compared to bulk GaN.

Zhenyu Zhang
Tao Wang
Xinqiang Wang
ResearchOpen Access30 Nov 2024
Nature Communications

Volume: 15, P: 1-8
Author Correction: A second-generation M1-polarized CAR macrophage with antitumor efficacy

Anhua Lei
Hua Yu
Jin Zhang
Amendments and Corrections18 Dec 2023
Nature Immunology

Volume: 25, P: 576
A tough semi-dry hydrogel electrode with anti-bacterial properties for long-term repeatable non-invasive EEG acquisition

Dongyang Wang
Hailing Xue
Jiaqi Lin
ResearchOpen Access26 May 2025
Microsystems & Nanoengineering

Volume: 11, P: 1-17
Prospective phase II trial of first-line rituximab, methotrexate, and orelabrutinib (R-MO) in primary central nervous system lymphoma

Lixia Sheng
Hailing Liu
Lei Fan
ResearchOpen Access29 Apr 2025
Blood Cancer Journal

Volume: 15, P: 1-8
A second-generation M1-polarized CAR macrophage with antitumor efficacy

Induced pluripotent stem cell (iPSC)-derived macrophages (iMACs) are being used to make chimeric antigen receptor (CAR) macrophages for immunotherapy. Here the authors design a second-generation macrophage-specific CAR by integrating CD3ζ and toll/IL-1R (TIR) domains resulting in an M1-polarized CAR-iMAC with increased antitumor functions.

Anhua Lei
Hua Yu
Jin Zhang
Research27 Nov 2023
Nature Immunology

Volume: 25, P: 102-116
Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation

Epigenetic reprogramming involves global loss of DNA methylation, but how this is regulated is not completely understood. Here, Tan et al. run a reverse genetic screen and report that nuclear DNMT1 is finetuned by maternal factor Pramel15 through proteasomal degradation in mouse zygotes.

Jiajun Tan
Yingfeng Li
Bing Zhu
ResearchOpen Access25 Aug 2024
Nature Communications

Volume: 15, P: 1-17
Atomic-scale visualization of defect-induced localized vibrations in GaN

Authors identify three types of defect-derived phonon modes in GaN, including localized defect modes, a confined bulk mode, and a fully extended mode. The defects exhibit a smaller phonon energy gap and lower sound speeds, indicating reduced thermal conductivity.

Hailing Jiang
Tao Wang
Xinqiang Wang
ResearchOpen Access20 Oct 2024
Nature Communications

Volume: 15, P: 1-9
Author Correction: De novo genome assembly and analyses of 12 founder inbred lines provide insights into maize heterosis

Baobao Wang
Mei Hou
Haiyang Wang
Amendments and Corrections02 Feb 2023
Nature Genetics

Volume: 55, P: 355
De novo genome assembly and analyses of 12 founder inbred lines provide insights into maize heterosis

De novo genome assembly and analyses of 12 maize FILs provide insights into genomic and phenotypic differentiation of various heterotic groups and the molecular basis of heterosis in maize.

Baobao Wang
Mei Hou
Haiyang Wang
Research16 Jan 2023
Nature Genetics

Volume: 55, P: 312-323
ARGONAUTE PIWI ___domain and microRNA duplex structure regulate small RNA sorting in Arabidopsis

Small RNA-binding ARGONAUTE proteins are important regulators of gene silencing and plant development. Here Zhang et al. identify conserved motifs in ArabidopsisARGONAUTE proteins that determine binding to specific microRNA duplex structures.

Xiaoming Zhang
DongDong Niu
Hailing Jin
Research19 Nov 2014
Nature Communications

Volume: 5, P: 1-11
Acquisition of aneuploidy drives mutant p53-associated gain-of-function phenotypes

Previous studies report that mutant p53 proteins have gain-of-function activities and cause oncogenic phenotypes. Herein, the authors engineered two isogenic epithelial cell lines to express wild-type or missense mutant p53 or be deficient for p53 protein and show that aneuploidy drives several of the GOF phenotypes previously ascribed to mutant p53.

Lindsay N. Redman-Rivera
Timothy M. Shaver
Jennifer A. Pietenpol
ResearchOpen Access31 Aug 2021
Nature Communications

Volume: 12, P: 1-15
The draft genome of the large yellow croaker reveals well-developed innate immunity

The large yellow croaker, Larimichthys crocea, is an economically important marine fish in China. Here, the authors sequence the draft genome of a wild large yellow croaker and highlight genes that may have played a role in the development of innate immunity in this species.

Changwen Wu
Di Zhang
Yun Liu
ResearchOpen Access19 Nov 2014
Nature Communications

Volume: 5, P: 1-7
A Study on Curing Kinetics of Nano-Phase Modified Epoxy Resin

Hailing Ma
Xin Zhang
Sang-Bing Tsai
ResearchOpen Access14 Feb 2018
Scientific Reports

Volume: 8, P: 1-15
Spatial atlas of the mouse central nervous system at molecular resolution

In situ spatial transcriptomic analysis of more than 1 million cells are used to create a 200-nm-resolution spatial molecular atlas of the adult mouse central nervous system and identify previously unknown tissue architectures.

Hailing Shi
Yichun He
Xiao Wang
ResearchOpen Access27 Sept 2023
Nature

Volume: 622, P: 552-561
Frequent alterations in cytoskeleton remodelling genes in primary and metastatic lung adenocarcinomas

Despite lung adenocarcinoma having a high global mortality, the genetic mutations present in Asian patients are uncharacterized. Here the authors use genomic and transcriptomic analysis to identify thirteen significantly affected genes, including RHPN2, GLI3, MRC2, TP53 and IQGAP3.

Kui Wu
Xin Zhang
Jianxing He
ResearchOpen Access09 Dec 2015
Nature Communications

Volume: 6, P: 1-13
Ocean wave energy harvesting with high energy density and self-powered monitoring system

Point-defect metamaterials have the property of concentrating vibration energy at the defect ___location. We design an environmental monitoring node based on this property, which can efficiently convert wave kinetic energy into electrical energy for real-time monitoring of the ocean environment.

Ze-Qi Lu
Long Zhao
Li-Qun Chen
ResearchOpen Access02 Aug 2024
Nature Communications

Volume: 15, P: 1-14
Genetic analyses support the contribution of mRNA N⁶-methyladenosine (m⁶A) modification to human disease heritability

Quantitative trait locus (QTL) mapping of N⁶-methyladenosine (m⁶A) in human cells highlights the role of RNA-binding proteins, RNA secondary structure and context-dependent m⁶A effects. m⁶A QTLs are enriched in loci associated with immune and blood-related traits.

Zijie Zhang
Kaixuan Luo
Chuan He
Research29 Jun 2020
Nature Genetics

Volume: 52, P: 939-949
Aridity-driven shift in biodiversity–soil multifunctionality relationships

Biodiversity-ecosystem functioning relationships may vary with climate. Here, the authors study relationships of plant and soil microbial diversity with soil nutrient multifunctionality in 130 dryland sites in China, finding a shift towards greater importance of soil microbial diversity in arid conditions.

Weigang Hu
Jinzhi Ran
Jianming Deng
ResearchOpen Access09 Sept 2021
Nature Communications

Volume: 12, P: 1-15
DNA demethylases are required for myo-inositol-mediated mutualism between plants and beneficial rhizobacteria

In Arabidopsis and tomato, exudation of myo-inositol by roots is epigenetically controlled by DNA demethylases and is involved in the beneficial recruitment of growth-promoting rhizobacteria.

Juan I. Vílchez
Yu Yang
Huiming Zhang
Research13 Jul 2020
Nature Plants

Volume: 6, P: 983-995
m⁶A facilitates hippocampus-dependent learning and memory through YTHDF1

Neuronal stimulation induces protein translation of m⁶A-methylated neuronal mRNAs facilitated by YTHDF1, and this process contributes to learning and memory.

Hailing Shi
Xuliang Zhang
Tao Zhou
Research31 Oct 2018
Nature

Volume: 563, P: 249-253
Disrupting CCDC137-mediated LZTS2 and β-TrCP interaction in the nucleus inhibits hepatocellular carcinoma development via β-catenin and AKT

Lei Xu
Qiumeng Liu
Jin Chen
Research25 Jun 2024
Cell Death & Differentiation

Volume: 32, P: 134-148
An RNA polymerase II- and AGO4-associated protein acts in RNA-directed DNA methylation

DNA methylation is an important epigenetic mark in many eukaryotes. In Arabidopsis plants, small interfering RNAs bound to the Argonaute 4 (AGO4) protein can direct de novo DNA methylation and consequent gene silencing. Here, a new regulator of RNA-directed DNA methylation has been discovered. This protein, RDM1, is proposed to bind to methylated DNA and to function in the AGO4 effector complex.

Zhihuan Gao
Hai-Liang Liu
Jian-Kang Zhu
Research21 Apr 2010
Nature

Volume: 465, P: 106-109
Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway–dependent and PI3K pathway–independent mechanisms

PI3K alterations are well-established drivers of breast cancer. However, PI3K-targeted therapy often results in treatment resistance and recurrence. By modeling PI3K tumorigenesis and inactivation in mice, this report shows that resistance may arise from alternative activation of the PI3K signaling pathway or by acquired alterations in other oncogenic drivers. As these mechanisms are also present in human tumors, they could be useful indicators to monitor and improve treatment responses.

Pixu Liu
Hailing Cheng
Jean J Zhao
Research07 Aug 2011
Nature Medicine

Volume: 17, P: 1116-1120
EGFR/SRC/ERK-stabilized YTHDF2 promotes cholesterol dysregulation and invasive growth of glioblastoma

EGFR is frequently constitutively active in glioblastoma (GBM). Here, the authors show that EGFR induces YTHDF2 protein stabilization, which reduces cholesterol homeostasis through an RNA m6A methylation dependent molecular mechanism to promote GBM tumourigenesis.

Runping Fang
Xin Chen
Suyun Huang
ResearchOpen Access08 Jan 2021
Nature Communications

Volume: 12, P: 1-17
Mechanically controlled reversible photoluminescence response in all-inorganic flexible transparent ferroelectric/mica heterostructures

An intriguing model system of flexible and transparent luminescent epitaxial thin film with highly tunable photoluminescence response is demonstrated by using the mica as substrate. The purely mechanical strain, instead of electric field, control of photoluminescence properties with superior stability, reversibility, and antifatigue behaviors shows promising applications in next-generation lightweight, transparent, flexible, and wearable passive optical devices.

Ming Zheng
Hailing Sun
K. W. Kwok
ResearchOpen Access27 Sept 2019
NPG Asia Materials

Volume: 11, P: 1-8
Genetic control of RNA splicing and its distinct role in complex trait variation

A powerful method for splicing quantitative trait loci (sQTL) mapping, THISTLE, is presented and applied to a collection of 2,865 brain samples. Integration with GWAS identifies 244 genes associated via cis-sQTLs, of which 61% were not identified using expression QTLs.

Ting Qi
Yang Wu
Jian Yang
ResearchOpen Access18 Aug 2022
Nature Genetics

Volume: 54, P: 1355-1363
AI-enabled diagnosis and localization of myocardial ischemia and coronary artery stenosis from magnetocardiographic recordings

Rong Tao
Shunlin Zhang
Guoyan Zheng
ResearchOpen Access19 Feb 2025
Scientific Reports

Volume: 15, P: 1-15
MiR-556-3p mediated repression of klotho under oxidative stress promotes fibrosis of renal tubular epithelial cells

Dong Zhang
Zongying Li
Hailing Sun
ResearchOpen Access09 Apr 2025
Scientific Reports

Volume: 15, P: 1-10
Understanding the high l-valine production in Corynebacterium glutamicum VWB-1 using transcriptomics and proteomics

Hailing Zhang
Yanyan Li
Xiaoyuan Wang
ResearchOpen Access26 Feb 2018
Scientific Reports

Volume: 8, P: 1-18
The aldose reductase inhibitor epalrestat exerts nephritic protection on diabetic nephropathy in db/db mice through metabolic modulation

Jun He
Hao-xue Gao
Guang-ji Wang
Research21 Jun 2018
Acta Pharmacologica Sinica

Volume: 40, P: 86-97
What is newsworthy about Covid-19? A corpus linguistic analysis of news values in reports by China Daily and The New York Times

Siyang Liu
Hailing Yu
ResearchOpen Access26 Oct 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-11
Exome sequencing reveals a heterozygous DLX5 mutation in a Chinese family with autosomal-dominant split-hand/foot malformation

Xue Wang
Qian Xin
Qiji Liu
Research05 Feb 2014
European Journal of Human Genetics

Volume: 22, P: 1105-1110
Integration of thermocouple microelectrode in the scanning electrochemical microscope at variable temperatures: simultaneous temperature and electrochemical imaging and its kinetic studies

He Pan
Hailing Zhang
Tao Jin
ResearchOpen Access24 Mar 2017
Scientific Reports

Volume: 7, P: 1-6
Highly Conductive Transparent Organic Electrodes with Multilayer Structures for Rigid and Flexible Optoelectronics

Xiaoyang Guo
Xingyuan Liu
Nan Zhang
ResearchOpen Access27 May 2015
Scientific Reports

Volume: 5, P: 1-9
Chromosome-level genome assembly of the crofton weed (Ageratina adenophora)

Fuyan Liu
Lin Du
Fanghao Wan
ResearchOpen Access02 Apr 2025
Scientific Data

Volume: 12, P: 1-11
A high-quality chromosome-scale assembly of the centipedegrass [Eremochloa ophiuroides (Munro) Hack.] genome provides insights into chromosomal structural evolution and prostrate growth habit

Jingjing Wang
Hailing Zi
Junqin Zong
ResearchOpen Access01 Sept 2021
Horticulture Research

Volume: 8, P: 1-13
MMFW-UAV dataset: multi-sensor and multi-view fixed-wing UAV dataset for air-to-air vision tasks

Yang Liu
Zhihao Sun
Fang Deng
ResearchOpen Access30 Jan 2025
Scientific Data

Volume: 12, P: 1-12
Identification and analysis of genes associated with the synthesis of bioactive constituents in Dendrobium officinale using RNA-Seq

Chenjia Shen
Hong Guo
Huizhong Wang
ResearchOpen Access15 Mar 2017
Scientific Reports

Volume: 7, P: 1-11
Archaeological textiles preserved by copper mineralization

Rui Jia
Hailing Zheng
Zhiqin Peng
ResearchOpen Access28 Aug 2024
Heritage Science

Volume: 12, P: 1-12
Effects of FGFR4 G388R, V10I polymorphisms on the likelihood of cancer

Tao Peng
Yangyang Sun
Yuanyuan Mi
ResearchOpen Access14 Jan 2021
Scientific Reports

Volume: 11, P: 1-12
Dysfunction of histone demethylase IBM1 in Arabidopsis causes autoimmunity and reshapes the root microbiome

Suhui Lv
Yu Yang
Huiming Zhang
ResearchOpen Access30 Jul 2022
The ISME Journal

Volume: 16, P: 2513-2524
In-situ observations reveal weak hygroscopicity in the Southern Tibetan Plateau: implications for aerosol activation and indirect effects

Yuan Wang
Jiming Li
Jianping Huang
ResearchOpen Access23 Mar 2024
npj Climate and Atmospheric Science

Volume: 7, P: 1-11
The proteomic characterization of the peritumor microenvironment in human hepatocellular carcinoma

Yuhan Gu
Yuanyuan Guo
Hailing Qiao
ResearchOpen Access21 Mar 2022
Oncogene

Volume: 41, P: 2480-2491
Content and activity of human liver microsomal protein and prediction of individual hepatic clearance in vivo

Haifeng Zhang
Na Gao
Hailing Qiao
ResearchOpen Access04 Dec 2015
Scientific Reports

Volume: 5, P: 1-12
Genome sequence of Kobresia littledalei, the first chromosome-level genome in the family Cyperaceae

Muyou Can
Wei Wei
Guangpeng Qu
ResearchOpen Access11 Jun 2020
Scientific Data

Volume: 7, P: 1-8
Correlations of SDF-1ɑ and XRCC1 gene polymorphisms with the risk of renal cancer development and bioinformatics studies of SDF-1α and XRCC1 and the prognosis of renal cancer

Wenjing Zhang
Yubo Su
Yumin Gao
ResearchOpen Access09 Feb 2024
Scientific Reports

Volume: 14, P: 1-12
Overexpression of fibulin-3 in tumor tissue predicts poor survival of malignant mesothelioma patients from hand-spinning asbestos exposed area in eastern China

Zhaoqiang Jiang
Wei Shen
Jianlin Lou
ResearchOpen Access23 Nov 2020
Scientific Reports

Volume: 10, P: 1-10
Hydrogel electrodes with conductive and substrate-adhesive layers for noninvasive long-term EEG acquisition

Hailing Xue
Dongyang Wang
Jiaqi Lin
ResearchOpen Access12 Jun 2023
Microsystems & Nanoengineering

Volume: 9, P: 1-14
Pan-cancer analysis reveals IGFL2 as a potential target for cancer prognosis and immunotherapy

Yuqi Wang
Hongwei Yuan
Yumin Gao
ResearchOpen Access13 Apr 2023
Scientific Reports

Volume: 13, P: 1-12

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