Zhu et al. designed and manufactured a mitral annuloplasty ring based on human high-resolution cardiac magnetic resonance imaging exams, demonstrating axis-specific flexibility and rigidity. This ring demonstrates excellent ex vivo hemodynamics and biomechanics while allowing mitral annulus dynamic changes in a survival in vivo large animal model.
- Yuanjia Zhu
- Annabel M. Imbrie-Moore
- Y. Joseph Woo