While progress has been made in the catalytic asymmetric synthesis of helicene (-like) molecules, the synthesis of multiple helicenes remains challenging. Herein, the authors report organocatalytic [4 + 2] cycloadditions to achieve double S-shaped quadruple helicene-like molecules with high enantioselectivity.
- Shengli Huang
- Haojun Wen
- Hailong Yan