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Showing 1–3 of 3 results
Advanced filters: Author: Helge Amthor Clear advanced filters

  • Marco Sandri, Helge Amthor, Stefano Piccolo and colleagues show that BMP signaling is a key positive regulator of muscle hypertrophy. They further show that inhibiting BMP signaling causes muscle atrophy, abolishes the hypertrophic phenotype of myostatin knockout mice and exacerbates the effects of denervation and fasting.

    • Roberta Sartori
    • Elija Schirwis
    • Marco Sandri
    Research
    Nature Genetics
    Volume: 45, P: 1309-1318

  • Skeletal muscle stem cells express the transcription factor Pax7. Here, the authors isolate, from human muscle, cells that are positive for the endothelial marker CLEC14A and show that despite not expressing pax7, these cells regenerate muscle and contribute to the muscle stem cell niche when transplanted into mice.

    • Andreas Marg
    • Helena Escobar
    • Simone Spuler
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-11