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Publisher Correction: Dynamic mRNA degradome analyses indicate a role of histone H3K4 trimethylation in association with meiosis-coupled mRNA decay in oocyte aging

Yun-Wen Wu
Sen Li
Qian-Qian Sha
Amendments and CorrectionsOpen Access15 Jun 2022
Nature Communications

Volume: 13, P: 1
CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes

The transcription-independent function of trimethylation of histone H3 (H3K4me) in cell division is unclear. Here, Heng-Yu Fan and colleagues report that CFP1, a subunit of the H3K4 methyltransferase, is required for oocyte meiosis, being phosphorylated and degraded during cell cycle transition.

Qian-Qian Sha
Xing-Xing Dai
Heng-Yu Fan
ResearchOpen Access28 Aug 2018
Nature Communications

Volume: 9, P: 1-17
Translation regulatory factor BZW1 regulates preimplantation embryo development and compaction by restricting global non-AUG Initiation

It is unclear how translational efficiency and codon stringency affect zygotic genome activation and early embryonic development. Here they show that the zygotic gene BZW1 increases start codon stringency, which is important for preimplantation development.

Jue Zhang
Shuai-Bo Pi
Heng-Yu Fan
ResearchOpen Access04 Nov 2022
Nature Communications

Volume: 13, P: 1-15
Dynamic mRNA degradome analyses indicate a role of histone H3K4 trimethylation in association with meiosis-coupled mRNA decay in oocyte aging

Developmental potential of oocytes decreases in women of advanced age. Here the authors observe impaired meiosis-coupled mRNA decay and reduced CXXC1-maintained histone H3K4 trimethylation in old oocytes of mouse and humans.

Yun-Wen Wu
Sen Li
Qian-Qian Sha
ResearchOpen Access09 Jun 2022
Nature Communications

Volume: 13, P: 1-17
Dynamics and clinical relevance of maternal mRNA clearance during the oocyte-to-embryo transition in humans

How maternal RNA clearance is regulated in human preimplantation embryos is unclear. Here, the authors show there is a potential correlation between maternal mRNA decay defects and early developmental arrest from in vitro fertilized human embryos, suggesting that M-decay and Z-decay pathways may regulate such early development.

Qian-Qian Sha
Wei Zheng
Heng-Yu Fan
ResearchOpen Access01 Oct 2020
Nature Communications

Volume: 11, P: 1-16
Selective inhibition of Tmem74 expression in BLA pyramidal neurons

Ling-Xiao Shao
Quan Jiang
Feng Han
Research18 Sept 2019
Molecular Psychiatry

Volume: 24, P: 1399
Metabolic remodelling during early mouse embryo development

By using an integrated omics approach, a landscape of metabolic remodelling of early-stage mouse embryogenesis is reconstructed, identifying key metabolites for epigenetic reprogramming.

Jing Zhao
Ke Yao
Jin Zhang
Research14 Oct 2021
Nature Metabolism

Volume: 3, P: 1372-1384
CRL4–DCAF1 ubiquitin E3 ligase directs protein phosphatase 2A degradation to control oocyte meiotic maturation

The E3 ubiquitin ligase CRL4 regulates oocyte survival through hydroxymethylation of genomic DNA. Here Yuet al. show that CRL4 is also required for oocytes to complete meiosis I by mediating the poly-ubiquitination and proteasomal degradation of the cell cycle regulator protein phosphatase 2A-A subunit.

Chao Yu
Shu-Yan Ji
Heng-Yu Fan
ResearchOpen Access18 Aug 2015
Nature Communications

Volume: 6, P: 1-11
BTG4 is a meiotic cell cycle–coupled maternal-zygotic-transition licensing factor in oocytes

B-cell translocation gene-4 (Btg4) bridges interactions of translation initiation factor eIF4E and CCR4–NOT deadenylase, thus triggering decay of maternal mRNA during mouse oocyte maturation.

Chao Yu
Shu-Yan Ji
Heng-Yu Fan
Research11 Apr 2016
Nature Structural & Molecular Biology

Volume: 23, P: 387-394
Ultrasensitive Ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development

Using an optimized Ribo-seq protocol that is applicable for low-input samples, Xie, Li and colleagues revealed the translation landscape during oocyte-to-embryo transition and in pre-implantation embryos.

Zhuqing Xiong
Kai Xu
Wei Xie
Research13 Jun 2022
Nature Cell Biology

Volume: 24, P: 968-980
Divergent projections of the prelimbic cortex mediate autism- and anxiety-like behaviors

Yi-Fan Luo
Lu Lu
Ying-Mei Lu
ResearchOpen Access23 Jan 2023
Molecular Psychiatry

Volume: 28, P: 2343-2354
Effects of MEK inhibitor U0126 on meiotic progression in mouse oocytes: microtuble organization, asymmetric division and metaphase II arrest

Chao TONG
Heng Yu FAN
Qing Yuan SUN
Research01 Oct 2003
Cell Research

Volume: 13, P: 375-383
HMCES safeguards genome integrity and long-term self-renewal of hematopoietic stem cells during stress responses

Yinghao Pan
Hongna Zuo
Li Shen
Research17 Jan 2022
Leukemia

Volume: 36, P: 1123-1131
Evolutionarily-conserved MZIP2 is essential for crossover formation in mammalian meiosis

Qianting Zhang et al. characterized the role of the mammalian ortholog of Zip2 in meiotic crossovers. Loss-of-function of MZIP2 leads to defects in DNA double-strand break repair, halting meiosis and causing sterility in both male and female mice.

Qianting Zhang
Jingchen Shao
Chao Yu
ResearchOpen Access21 Sept 2018
Communications Biology

Volume: 1, P: 1-10
Loss of oocyte Rps26 in mice arrests oocyte growth and causes premature ovarian failure

Xiao-Man Liu
Ming-Qi Yan
Zi-Jiang Chen
ResearchOpen Access19 Nov 2018
Cell Death & Disease

Volume: 9, P: 1-15
Mammalian nucleolar protein DCAF13 is essential for ovarian follicle maintenance and oocyte growth by mediating rRNA processing

Jue Zhang
Yin-Li Zhang
Heng-Yu Fan
Research03 Oct 2018
Cell Death & Differentiation

Volume: 26, P: 1251-1266
Maternal DCAF13 Regulates Chromatin Tightness to Contribute to Embryonic Development

Yang Liu
Long-Wen Zhao
Yan Jin
ResearchOpen Access18 Apr 2019
Scientific Reports

Volume: 9, P: 1-11
Functional coupling of Tmem74 and HCN1 channels regulates anxiety-like behavior in BLA neurons

Ling-Xiao Shao
Quan Jiang
Feng Han
Research18 Mar 2019
Molecular Psychiatry

Volume: 24, P: 1461-1477
Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse

Chao Yu
Shu-Yan Ji
Heng-Yu Fan
ResearchOpen Access23 Feb 2016
Cell Research

Volume: 26, P: 275-287
High salt primes a specific activation state of macrophages, M(Na)

Wu-Chang Zhang
Xiao-Jun Zheng
Sheng-Zhong Duan
ResearchOpen Access24 Jul 2015
Cell Research

Volume: 25, P: 893-910

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