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Showing 1–9 of 9 results
Advanced filters: Author: Henrik Renner Clear advanced filters

  • Single-nucleus RNA-sequencing data from the cerebellum of human, mouse and opossum is used to analyse the developmental dynamics of cell types and states in mammalian cerebellum and provide evolutionary insights.

    • Mari Sepp
    • Kevin Leiss
    • Henrik Kaessmann
    ResearchOpen Access
    Nature
    Volume: 625, P: 788-796

  • The focus of much of contemporary research ethics is on compliance with established protocols. However, large data-driven neuroscience research raises new ethical concerns that have no agreed-upon solution. Here we reflect on these challenges and propose better integration of public and patient involvement in this evolving landscape.

    • Bernd Carsten Stahl
    • George Ogoh
    • Bernd Stahl
    Comments & Opinion
    Nature Mental Health
    Volume: 2, P: 1128-1130

  • Analyses of data from the UK Biobank reveal different urban living environments that are associated with affective, anxiety and emotional instability symptom groups and mediated by distinct neurological and genetic pathways in adults.

    • Jiayuan Xu
    • Nana Liu
    • George Ogoh
    ResearchOpen Access
    Nature Medicine
    Volume: 29, P: 1456-1467

  • This Comment explores new approaches to enrich large-scale population data, including incorporating macro-environmental and digital health measures.

    • Frauke Nees
    • Paul Renner
    • George Ogoh
    Comments & Opinion
    Nature Mental Health
    Volume: 2, P: 1124-1127

  • This Comment presents a high-level protocol for data harmonization within large cohorts, in which it postulates four main steps including (1) expert review, (2) pre-statistical harmonization, (3) statistical harmonization, and (4) validation.

    • Maja Neidhart
    • Rikka Kjelkenes
    • George Ogoh
    Comments & Opinion
    Nature Mental Health
    Volume: 2, P: 1134-1137

  • Integrative analyses that incorporate different levels of ‘-omics’ data represent a powerful tool for deciphering the biological mechanisms that underlie environmental influences on mental health and disease. This Comment highlights various aspects of such multi-omics approaches, using the example of the EU-funded environMENTAL project.

    • Sylvane Desrivières
    • Abigail Miller
    • George Ogoh
    Comments & Opinion
    Nature Mental Health
    Volume: 2, P: 1131-1133