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Showing 1–50 of 80 results

Advanced filters: Author: Hui Dou Clear advanced filters

A mouse brain stereotaxic topographic atlas with isotropic 1-μm resolution

A stereotaxic atlas of the whole mouse brain, based on a Nissl-stained cytoarchitecture dataset with isotropic 1-μm resolution, achieved through continuous micro-optical sectioning tomography, promises to be a versatile brainsmatics tool for studying the whole brain at single-cell level.

Zhao Feng
Xiangning Li
Qingming Luo
ResearchOpen Access02 Jul 2025
Nature

P: 1-9
WSTF nuclear autophagy regulates chronic but not acute inflammation

During chronic but not acute inflammation, chromatin remodelling is influenced by nuclear autophagy through WSTF interaction with ATG8 in the nucleus, leading to WSTF nuclear export and its subsequent degradation.

Yu Wang
Vinay V. Eapen
Zhixun Dou
Research02 Jul 2025
Nature

P: 1-10
Photoinduced bulk polymerization strategy in melt state for recyclable polydiene derivatives

Polydienes are essential in industry but rely on a complex synthesis involving catalysts and solvents. Now it is shown that photo-melt-bulk polymerization enables the solvent- and catalyst-free synthesis of controlled high-molecular-weight polydienes by combining chain growth and the coupling of stable biradicals, advancing sustainable materials development.

Pengfei Wu
Qixuan Hu
Letian Dou
Research28 May 2025
Nature Chemistry

Volume: 17, P: 1091-1098
Development and evaluation of cepharanthine-β-cyclodextrin inclusion complex oral tablets for prevention and treatment of COVID-19 lung injury

Di Liang
Zihan Lv
Guifang Dou
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-16
Telomere-to-telomere genome assembly of a male goat reveals variants associated with cashmere traits

Species genomes are important for analyses of genetic variation. Wu et al. assembled a T2T genome of a male cashmere goat, including 288.5 Mb of previously unresolved regions, and identified selective variants and genes associated with domestication and cashmere traits.

Hui Wu
Ling-Yun Luo
Meng-Hua Li
ResearchOpen Access20 Nov 2024
Nature Communications

Volume: 15, P: 1-20
Ultrahigh electromechanical response from competing ferroic orders

Ultrahigh electromechanical response is accomplished by inducing extreme structural instability from competing antiferroelectric and ferroelectric orders.

Baichen Lin
Khuong Phuong Ong
Huajun Liu
ResearchOpen Access11 Sept 2024
Nature

Volume: 633, P: 798-803
Functional screening and rational design of compounds targeting GPR132 to treat diabetes

This study presents a comprehensive pipeline to profile transmembrane receptors involved in macrophage-driven inflammation in pancreatic islets during the onset of diabetes. The authors identify GPR132 as a mediator of macrophage-driven inflammation and find compounds that reduce inflammation and improve glycaemic control.

Jia-Le Wang
Xiao-Dong Dou
Xiao Yu
Research28 Sept 2023
Nature Metabolism

Volume: 5, P: 1726-1746
A skin disease classification model based on multi scale combined efficient channel attention module

Hui Liu
Yibo Dou
Huling Li
ResearchOpen Access19 Feb 2025
Scientific Reports

Volume: 15, P: 1-17
Quantitative determination of acetylshikonin in macaque monkey blood by LC-ESI-MS/MS after precolumn derivatization with 2-mercaptoethanol and its application in pharmacokinetic study

Dong-xiao Sun
Hui-fang Tian
Gui-fang Dou
Research01 Dec 2008
Acta Pharmacologica Sinica

Volume: 29, P: 1499-1506
SHAP-enhanced interpretive MGTWR-CNN-BILSTM-AM framework for predicting surface subsidence: a case study of Shanghai municipality

Long Wen-Jiang
Yu Xue-Xiang
Wang Lin-Lin
ResearchOpen Access05 Jun 2025
Scientific Reports

Volume: 15, P: 1-21
The role of transposon inverted repeats in balancing drought tolerance and yield-related traits in maize

Transposon-associated inverted repeats play a role in drought resistance and yield-related traits in maize.

Xiaopeng Sun
Yanli Xiang
Mingqiu Dai
Research13 Oct 2022
Nature Biotechnology

Volume: 41, P: 120-127
Erratum: Comparative genomics reveals adaptive evolution of Asian tapeworm in switching to a new intermediate host

Shuai Wang
Sen Wang
Xuepeng Cai
Amendments and CorrectionsOpen Access03 Nov 2016
Nature Communications

Volume: 7, P: 1-2
Nickel sulfide nanocrystals on nitrogen-doped porous carbon nanotubes with high-efficiency electrocatalysis for room-temperature sodium-sulfur batteries

Room temperature rechargeable sodium sulfur batteries are promising for next-generation energy storage systems, but their development is limited by polysulfide dissolution and slow kinetics. Here the authors report a cathode that serves as a multifunctional sulfur host and imparts enhanced performance.

Zichao Yan
Jin Xiao
Shi-Xue Dou
ResearchOpen Access22 Oct 2019
Nature Communications

Volume: 10, P: 1-8
Dual-comb spectroscopy over a 100 km open-air path

Dual-comb spectroscopy with time–frequency dissemination and high-power frequency combs enables sensing CO₂ and H₂O over a 113 km turbulent open-air path, with a sensing precision as high as 2 parts per million of CO₂.

Jin-Jian Han
Wei Zhong
Jian-Wei Pan
Research12 Sept 2024
Nature Photonics

Volume: 18, P: 1195-1202
A conserved oomycete effector RxLR23 triggers plant defense responses by targeting ERD15La to release NbNAC68

This study demonstrated how the oomycete effector RxLR23^KM can trigger plant defense responses by interacting with NbERD15La, a regulator of abscisic acid and salicylic acid pathways in tobacco, which in turn regulates the downstream immune activator NbNAC68.

Hui Sheng
Congcong Ai
Xiuguo Zhang
ResearchOpen Access27 Jul 2024
Nature Communications

Volume: 15, P: 1-23
Scallop genome provides insights into evolution of bilaterian karyotype and development

The genome of the scallop Patinopecten yessoensis is sequenced. This bivalve mollusc has a slow-evolving genome with features such as karyotype and Hox gene expression that may be close to that of the ancestral bilaterian.

Shi Wang
Jinbo Zhang
Zhenmin Bao
ResearchOpen Access03 Apr 2017
Nature Ecology & Evolution

Volume: 1, P: 1-12
Chinese college students’ post-traumatic growth during the COVID-19: a grounded theory study

Yining Ma
Hui Wang
Zaoyi Sun
ResearchOpen Access29 Mar 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-11
Switch of cell migration modes orchestrated by changes of three-dimensional lamellipodium structure and intracellular diffusion

How do cells regulate their migration speed and direction? Here, authors discover that keratocyte cells can reversibly switch between different migration modes, by changing the 3D lamellipodium shape and intracellular diffusion.

Chao Jiang
Hong-Yu Luo
Hui Li
ResearchOpen Access24 Aug 2023
Nature Communications

Volume: 14, P: 1-13
Quantitative sequencing using BID-seq uncovers abundant pseudouridines in mammalian mRNA at base resolution

Pseudouridine sites in mRNA are detected at base resolution and functionally investigated.

Qing Dai
Li-Sheng Zhang
Chuan He
ResearchOpen Access27 Oct 2022
Nature Biotechnology

Volume: 41, P: 344-354
A pilot study of neoadjuvant combination of anti-PD-1 camrelizumab and VEGFR2 inhibitor apatinib for locally advanced resectable oral squamous cell carcinoma

In patients with locally advanced resectable oral squamous cell carcinoma (OSCC), the risk of recurrence and metastasis following treatment is high. Here, a phase I clinical trial reports safety and pathological response of neoadjuvant camrelizumab and apatinib in patients with locally advanced resectable OSCC.

Wu-tong Ju
Rong-hui Xia
Lai-ping Zhong
ResearchOpen Access14 Sept 2022
Nature Communications

Volume: 13, P: 1-11
Irx3 and Irx5 in Ins2-Cre⁺ cells regulate hypothalamic postnatal neurogenesis and leptin response

Irx3 and Irx5 are effectors of the FTO locus, which is associated with obesity. Son et al. show regulation of hypothalamic neurogenesis by Irx3 and Irx5, uncovering a role for these genes in leptin response and energy homeostasis.

Joe Eun Son
Zhengchao Dou
Chi-chung Hui
Research15 Apr 2021
Nature Metabolism

Volume: 3, P: 701-713
Enabling giant thermopower by heterostructure engineering of hydrated vanadium pentoxide for zinc ion thermal charging cells

The application of zinc ion thermal charging cells has been limited by their low kinetics and rapid energy decay. Here, the authors develop a promising material by heterostructure engineering of hydrated vanadium pentoxide for high-performance harvesting and conversion of low-grade heat.

Zhiwei Li
Yinghong Xu
Xiaogang Zhang
ResearchOpen Access26 Oct 2023
Nature Communications

Volume: 14, P: 1-11
Surface treatment of red painted and slipped wares in the middle Yangtze River valley of Late Neolithic China: multi-analytical case analysis

Tao Li
Guoyuan Li
Lihua Wang
ResearchOpen Access21 Nov 2022
Heritage Science

Volume: 10, P: 1-22
Dynamic profile of differentiated thyroid cancer in male and female patients with thyroidectomy during 2000–2013 in China: a retrospective study

Hui-xian Yan
Ping Pang
Zhao-hui Lyu
ResearchOpen Access20 Nov 2017
Scientific Reports

Volume: 7, P: 1-8
Myxobacteria restrain Phytophthora invasion by scavenging thiamine in soybean rhizosphere via outer membrane vesicle-secreted thiaminase I

The plant pathogen Phytophthora sojae requires exogenous thiamine for growth. Here, Li et al. show that soil myxobacteria inhibit Phytophthora’s growth by scavenging thiamine through the secretion a thiaminase via outer membrane vesicles.

Chengyao Xia
Yuqiang Zhao
Zhongli Cui
ResearchOpen Access13 Sept 2023
Nature Communications

Volume: 14, P: 1-16
Pulmonary nodules detection based on multi-scale attention networks

Hui Zhang
Yanjun Peng
Yanfei Guo
ResearchOpen Access27 Jan 2022
Scientific Reports

Volume: 12, P: 1-14
Hierarchical porous carbons with layer-by-layer motif architectures from confined soft-template self-assembly in layered materials

2D nanomaterials are promising capacitive energy storage materials, but their tendency to restack hinders electrolyte transport. Here, Yamauchi and colleagues introduce 2D ordered mesoporous carbons in between MXene layers, and metal removal affords all-carbon porous 2D–2D heterostructures in which restacking is prevented.

Jie Wang
Jing Tang
Yusuke Yamauchi
ResearchOpen Access12 Jun 2017
Nature Communications

Volume: 8, P: 1-9
Zinc ion thermal charging cell for low-grade heat conversion and energy storage

Low-grade heat conversion has recently emerged and displayed great promise in sustainable electronics and energy areas. Here, the authors propose a new zinc ion thermal charging cell with hybrid behaviours for high value-added conversion from heat to electricity.

Zhiwei Li
Yinghong Xu
Xiaogang Zhang
ResearchOpen Access10 Jan 2022
Nature Communications

Volume: 13, P: 1-10
Astragaloside IV improves lipid metabolism in obese mice by alleviation of leptin resistance and regulation of thermogenic network

Hui Wu
Yan Gao
Xiao-Jun Wu
ResearchOpen Access22 Jul 2016
Scientific Reports

Volume: 6, P: 1-11
A flexible metal–organic framework with a high density of sulfonic acid sites for proton conduction

Proton-conducting metal-organic frameworks (MOFs) could be used as the electrolytes in proton exchange membrane fuel cells but chemically stable materials that perform well at low humidity are still sought. Here the authors prepare a stable, structurally flexible MOF that maintains high proton conductivity under a wide range of humidity.

Fan Yang
Gang Xu
Banglin Chen
Research16 Oct 2017
Nature Energy

Volume: 2, P: 877-883
Current evidence on circRNAs as potential theranostic markers for detecting chemoresistance in breast cancer: a systematic review and meta‑analysis

Zixin Zhu
Hui Jiang
Jinbo Liu
ResearchOpen Access20 Dec 2022
Scientific Reports

Volume: 12, P: 1-10
Comparative genomics reveals adaptive evolution of Asian tapeworm in switching to a new intermediate host

Only one of the three Taenia species causing taeniasis in humans was previously sequenced. Here the authors provide draft genomes of Taenia saginata and Taenia asiatica, analyse genome evolution of all three species, and identify potential targets for developing diagnostic markers or intervention tools.

Shuai Wang
Sen Wang
Xuepeng Cai
ResearchOpen Access22 Sept 2016
Nature Communications

Volume: 7, P: 1-12
Gut microbiota, inflammatory cytokines, and Kawasaki disease: a Mendelian randomization study and mediation analysis

Ji-Gan Wang
Hui-Hong Dou
Qiong-You Liang
Research10 Feb 2025
Pediatric Research

P: 1-5
Anti-EGFR therapy can overcome acquired resistance to the third-generation ALK-tyrosine kinase inhibitor lorlatinib mediated by activation of EGFR

Chen Hu
Cong-hua Lu
Yong He
Research21 Mar 2025
Acta Pharmacologica Sinica

P: 1-15
Destabilizing heterochromatin by APOE mediates senescence

Apolipoprotein E (APOE) is a lipoprotein particle component and is genetically linked to human longevity and Alzheimer’s disease; however, the mechanisms that link APOE and aging are incompletely understood. Here, Zhao et al. show that APOE drives cellular senescence in aged human mesenchymal progenitor cells by destabilizing heterochromatin.

Hongkai Zhao
Qianzhao Ji
Guang-Hui Liu
Research28 Mar 2022
Nature Aging

Volume: 2, P: 303-316
Hypoxia-induced epithelial-mesenchymal transition and fibrosis for the development of breast capsular contracture

Yao-Lung Kuo
I-Ming Jou
Ting-Mao Chou
ResearchOpen Access16 Jul 2019
Scientific Reports

Volume: 9, P: 1-6
Boosting adversarial transferability in vision-language models via multimodal feature heterogeneity

Long Chen
Yuling Chen
Haiwei Sang
ResearchOpen Access02 Mar 2025
Scientific Reports

Volume: 15, P: 1-22
Female gender lost protective effect against disease progression in elderly patients with chronic hepatitis B

Hong You
Yuanyuan Kong
Jidong Jia
ResearchOpen Access28 Nov 2016
Scientific Reports

Volume: 6, P: 1-7
Pharmacokinetics and pharmacodynamics of SCT800, a new recombinant FVIII, in hemophilia A mice

Ruo-lan Gu
Liang Liu
Gui-fang Dou
Research25 Jan 2016
Acta Pharmacologica Sinica

Volume: 37, P: 408-414
Deep learning model for the prediction of all-cause mortality among long term care people in China: a prospective cohort study

Huai-Cheng Tan
Li-Jun Zeng
Qing-Yu Dou
ResearchOpen Access25 Jun 2024
Scientific Reports

Volume: 14, P: 1-11
The Schistosoma japonicum genome reveals features of host–parasite interplay

Schistosoma mansoni and Schistosoma japonicum are the pathogenic agents that cause the tropical disease schistosomiasis. Here, and in an accompanying paper, the genomes of these two flatworms are sequenced and analysed. The results provide insights into the molecular architecture and host interactions of the flatworms, as well as avenues for future development of targeted interventions for schistosomiasis.

Yan Zhou
Huajun Zheng
Zhu Chen
ResearchOpen Access16 Jul 2009
Nature

Volume: 460, P: 345-351
The prevalence of masked hypertension and masked uncontrolled hypertension in relation to overweight and obesity in a nationwide registry in China

Our study showed that overweight and obesity were associated with a higher prevalence of masked uncontrolled hypertension but not masked hypertension, indicating that clinic blood pressure might overestimate antihypertensive treatment effects in patients with overweight and obesity.

Jia-Hui Xia
Dong-Yan Zhang
Ji-Guang Wang
Research14 Sept 2022
Hypertension Research

Volume: 45, P: 1690-1700
THBru attenuates diabetic cardiomyopathy by inhibiting RAGE-dependent inflammation

Heng-hui Xu
Sheng-xin Hao
Yong Zhang
Research11 Jun 2024
Acta Pharmacologica Sinica

Volume: 45, P: 2107-2118
Accelerated sulfate reducing bacteria corrosion of X80 pipeline steel welded joints under organic carbon source starvation

Qin Wang
Xiaobao Zhou
Tangqing Wu
ResearchOpen Access27 Sept 2022
npj Materials Degradation

Volume: 6, P: 1-12
Mettl1 knockdown alleviates cardiac I/R injury in mice by inactivating the Mettl1-CYLD-P53 positive feedback loop

Shu-ting Yu
Zhi-yong Sun
Wei-jie Du
Research16 Oct 2024
Acta Pharmacologica Sinica

Volume: 46, P: 592-605
Author Correction: THBru attenuates diabetic cardiomyopathy by inhibiting RAGE-dependent inflammation

Heng-hui Xu
Sheng-xin Hao
Yong Zhang
Amendments and Corrections30 Jan 2025
Acta Pharmacologica Sinica

Volume: 46, P: 1795-1796
Effects of interspecific interaction-linked habitat factors on moose resource selection and environmental stress

Heng Bao
John M. Fryxell
Guangshun Jiang
ResearchOpen Access27 Jan 2017
Scientific Reports

Volume: 7, P: 1-10
Development and clinical application of deep learning model for lung nodules screening on CT images

Sijia Cui
Shuai Ming
Haochu Wang
ResearchOpen Access12 Aug 2020
Scientific Reports

Volume: 10, P: 1-10
Analysis of microglial migration by a micropipette assay

Hang-jun Wu
Yi-jun Liu
Shumin Duan
Protocols30 Jan 2014
Nature Protocols

Volume: 9, P: 491-500
Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial

Jun Liu
Dan-Dan Li
Zhong Wang
ResearchOpen Access01 Sept 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-10

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